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Journals / Journal of the Turkish Chemical Society Section A: Chemistry / 2016 / Cilt: 3 - Sayı: 3

SYNTHESIS, CHARACTERIZATION AND ANTIOXIDANT ACTIVITIES OF NOVEL 1-(MORPHOLINE-4-YL-METHYL)-3-ALKYL(ARYL)-4-[4-(DIMETHYLAMINO)-BENZYLIDENAMINO]-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-5-ONES

Özlem Gürsoy Kol
Haydar Yüksek
Sevda Manap
Feyzi Sinan Tokalı
Pages
105–118
Publication Date
2017-01-08
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

All of the compounds demonstrated significant activity for metal chelating effect.

📌 3 Key Takeaways

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Objective & Hypothesis:In this paper, eight novel 1-(morpholine-4-yl-methyl)-3-alkyl(aryl)-4-[4-(dimethylamino)-benzylidenamino]-4,5-dihydro-1H-1,2,4-triazol-5-ones (2) were obtained by the reactions of 3-alkyl(aryl)-4-[4-(dimethylamino)-benzylidenamino]-4,5-dihydro-1H-1,2,4-triazol-5-ones (1) with formaldehyde and morpholine.
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Key Findings & Data:The novel synthesized compounds were identified by IR, 1H NMR and 13C NMR spectral data.
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Conclusion & Impact:All of the compounds demonstrated significant activity for metal chelating effect.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:5-Dihydro-1H-1 · 4-triazol-5-one · Syntheses

Abstract

In this paper, eight novel 1-(morpholine-4-yl-methyl)-3-alkyl(aryl)-4-[4-(dimethylamino)-benzylidenamino]-4,5-dihydro-1H-1,2,4-triazol-5-ones (2) were obtained by the reactions of 3-alkyl(aryl)-4-[4-(dimethylamino)-benzylidenamino]-4,5-dihydro-1H-1,2,4-triazol-5-ones (1) with formaldehyde and morpholine. The novel synthesized compounds were identified by IR, 1H NMR and 13C NMR spectral data. Besides, the newly synthesized compounds were analysed for their in vitro potential antioxidant capacities in three different assays. All of the compounds demonstrated significant activity for metal chelating effect.

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Cite This Article

Kol, Ö. G., Yüksek, H., Manap, S., Tokalı, F. S. (2017). SYNTHESIS, CHARACTERIZATION AND ANTIOXIDANT ACTIVITIES OF NOVEL 1-(MORPHOLINE-4-YL-METHYL)-3-ALKYL(ARYL)-4-[4-(DIMETHYLAMINO)-BENZYLIDENAMINO]-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-5-ONES. Journal of the Turkish Chemical Society Section A: Chemistry, Cilt: 3 - Sayı: 3, 105–118. https://ajindex.com/articles/781631

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