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Journals / Journal of Surgery and Medicine / 2018 / Cilt: 2 - Sayı: 3

A case of langerhans cell histiocytosis associated with mantle cell lymphoma

Mantle hücreli lenfoma ile birliktelik gösteren bir langerhans hücreli histiyositozis olgusu

Gülen Gül
Mehmet Ali Özcan
Fatih Demirkan
Sermin Özkal
Pages
361–363
Publication Date
2018-09-01
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

To the best of our knowledge, this is the second reported case of LCH associated with mantle cell lymphoma in a lymph node.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Langerhans Cell Histiocytosis (LCH), which is caused by neoplastic clonal proliferation of Langerhans cells, may be associated with various malignant neoplasms, especially lymphomas, in rare cases.
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Key Findings & Data:In literature some studies observed an unexpected number of second malignancies, both prior to and after the diagnosis of MCL.
💡
Conclusion & Impact:To the best of our knowledge, this is the second reported case of LCH associated with mantle cell lymphoma in a lymph node.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Langerhans hücreli histiyositozis · Mantle hücreli lenfoma · Lenfoma

Abstract

Langerhans Cell Histiocytosis (LCH), which is caused by neoplastic clonal proliferation of Langerhans cells, may be associated with various malignant neoplasms, especially lymphomas, in rare cases. In literature some studies observed an unexpected number of second malignancies, both prior to and after the diagnosis of MCL. Here, we report a case with concurrent LCH and mantle cell lymphoma (MCL) in a same lymph node. To the best of our knowledge, this is the second reported case of LCH associated with mantle cell lymphoma in a lymph node.

Özet

Langerhans hücrelerinin neoplastik klonal proliferasyonundan oluşan Langerhans Hücreli Histiyositozis (LHH) nadir durumlarda, özellikle lenfomalar olmak üzere çeşitli malign neoplaziler ile ilişkili olabilir. Literatürdeki bazı çalışmalarda MHL tanısı öncesi ve sonrasında, beklenmeyen sayıda ikincil malignite olduğu görülmüştür. Burada aynı lenf nodunda LHH ve mantle hücreli lenfoma (MHL) birlikteliği olan bir olgu sunulmaktadır. Bildiğimiz kadarıyla, bu olgu MHL ve LHH birlikteliği olan ikinci vakadır.

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Cite This Article

Gül, G., Özcan, M. A., Demirkan, F., Özkal, S. (2018). A case of langerhans cell histiocytosis associated with mantle cell lymphoma. Journal of Surgery and Medicine, Cilt: 2 - Sayı: 3, 361–363. https://ajindex.com/articles/780711

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