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Journals / Journal of Surgery and Medicine / 2020 / Cilt: 4 - Sayı: 4

The effect of iron carboxymaltose treatment on quality of life in women with iron deficiency

Demir eksikliği olan kadınlarda demir karboksimaltoz tedavisinin hayat kalitesine etkisi

Çağlar HELVACIOĞLU
Murat EKİN
Pages
259–262
Publication Date
2020-04-01
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Iron deficiency should be replaced effectively.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Iron deficiency is the most common cause of anemia in over the world and affects 20% of women, even in developed countries.
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Key Findings & Data:In this study, our aim is to calculate the change in the quality of life of patients treated with parenteral ferric carboxymaltose.Methods: In this retrospective cohort study, quality of life scores were evaluated before and after 6 weeks of treatment using the Short Form 36 scale.
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Conclusion & Impact:Iron deficiency should be replaced effectively.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Demir · Anemi · Yaşam kalitesi

Abstract

Aim: Iron deficiency is the most common cause of anemia in over the world and affects 20% of women, even in developed countries. In this study, our aim is to calculate the change in the quality of life of patients treated with parenteral ferric carboxymaltose.Methods: In this retrospective cohort study, quality of life scores were evaluated before and after 6 weeks of treatment using the Short Form 36 scale. Fifty patients receiving parenteral ferric carboxymaltose treatment in Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Department of Gynecology and Obstetrics were included. Results: Pretreatment ad posttreatment hemoglobin values were 8.22 g/dl and 12.02 g/dl, respectively. Pretreatment physical role functioning score was 34.7 (39) and it was calculated as 54.2 (39.8) after the treatment (P=0.006). There were no significant differences between pre- and post-treatment emotional strength, (P=0.330), energy vitality, (P=0.210), mental health (P=0.910) scores and sub-dimensions. Minor side effects were observed in 3 patients.Conclusion: Parenteral ferric carboxymaltose therapy significantly improves quality of life, especially physical role strength. Iron deficiency should be replaced effectively.

Özet

Amaç: Demir eksikliği anemisi; en sık tespit edilen anemi nedeni olup, gelişmiş ülkelerde bile kadınların %20’sini etkilemektedir. Bu çalışmada parenteral ferrik karboksimaltoz tedavisinin hastaların yaşam kalitesine olan etkisi değerlendirilmiştir.Yöntemler: Bu retrospektif kohort çalışma SBÜ Bakırköy Dr. Sadi Konuk Eğitim ve Araştırma Hastanesi Kadın Hastalıkları ve Doğum Kliniği’nde yapılmıştır. Parenteral ferrik karboksimaltoz tedavisi verilen 50 hastada, tedavi öncesi ve sonrası 6. hafta arasında yaşam kalitesi açısından değişim; Kısa Form 36 ölçeği kullanılarak değerlendirilmiştir.Bulgular: Tedavi öncesi hemoglobin düzeyi 8,22 gr/dl iken tedavi sonrası 6. Haftada 12,02 gr/dl düzeyine yükselmiştir. Tedavi öncesi 34,7 (39) olan fiziksel rol güçlüğü, tedavi sonrasında 54,2 (39,8)’e yükselmiştir (P=0,006). Emosyonel rol güçlüğü, (P=0,330), enerji canlılık (P=0,210) ve ruh sağlığı (P=0,910) alt boyutlarında anlamlı farklılık olmadığı saptanmıştır. 3 hastada minör yan etki gözlenmiştir.Sonuç: Parenteral demir karboksimaltoz tedavisi özellikle fiziksel rol güçlüğü kategorisinde olmak üzere yaşam kalitesini belirgin şekilde artırmıştır. Bu yüzden demir eksikliği etkili bir şekilde replase edilmelidir.

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Cite This Article

HELVACIOĞLU, Ç., EKİN, M. (2020). The effect of iron carboxymaltose treatment on quality of life in women with iron deficiency. Journal of Surgery and Medicine, Cilt: 4 - Sayı: 4, 259–262. https://ajindex.com/articles/780358

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