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Journals / Journal of Surgery and Medicine / 2022 / Cilt: 6 - Sayı: 4

The healing effects of Ganoderma lucidum on intestinal ischemia-reperfusion damage in rats

Muhammed GÖMEÇ
Bahadır KÜLAH
Uğur ERCAN
Sevinç ŞAHİN
Pages
476–482
Publication Date
2022-04-01
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

Results: The I/R group had significantly elevated leukocyte, thrombocyte, serum, and intestinal and hepatic tissue MDA levels compared to the sham group (P

📌 3 Key Takeaways

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Objective & Hypothesis:Background/Aim: Intestinal ischemia-reperfusion (I/R) injury causes serious clinical problems and carries high morbidity and mortality risks.
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Key Findings & Data:After 30/90 minutes of I/R, intestinal and hepatic tissue examples were histologically examined.
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Conclusion & Impact:Results: The I/R group had significantly elevated leukocyte, thrombocyte, serum, and intestinal and hepatic tissue MDA levels compared to the sham group (P
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Antioxidative · Anti-inflammatory · Immunomodulator

Abstract

Background/Aim: Intestinal ischemia-reperfusion (I/R) injury causes serious clinical problems and carries high morbidity and mortality risks. Ganoderma lucidum (GL) is known as an anti-inflammatory immunomodulator and antioxidant. This study aimed to investigate the curative effects of GL on intestinal I/R injury in rats. Methods: Twenty-four Wistar-Albino male rats were randomly divided into three groups. After 30/90 minutes of I/R, intestinal and hepatic tissue examples were histologically examined. Biochemical analysis, serum, intestinal and hepatic tissue malondialdehyde (MDA), glutathione peroxidase (GSH-Px), and superoxide dismutase (SOD) levels were measured. Results: The I/R group had significantly elevated leukocyte, thrombocyte, serum, and intestinal and hepatic tissue MDA levels compared to the sham group (P

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Cite This Article

GÖMEÇ, M., KÜLAH, B., ERCAN, U., ŞAHİN, S. (2022). The healing effects of Ganoderma lucidum on intestinal ischemia-reperfusion damage in rats. Journal of Surgery and Medicine, Cilt: 6 - Sayı: 4, 476–482. https://ajindex.com/articles/779675

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