Journals / Journal of Surgery and Medicine / 2022 / Cilt: 6 - Sayı: 5

Do myometrial lesions affect the discrepancy of pathological findings in women with endometrial hyperplasia?

Pages
557–560
Publication Date
2022-05-01
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Results: The overall diagnostic concordance between the endometrial sampling results and the final hysterectomy pathologic findings was 32.2%.

📌 3 Key Takeaways

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Objective & Hypothesis:Background/Aim: Benign myometrial lesions are frequently found in pathologic specimens of hysterectomies.
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Key Findings & Data:High rates of coexistence of these lesions with endometrial cancer have also been reported.
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Conclusion & Impact:Results: The overall diagnostic concordance between the endometrial sampling results and the final hysterectomy pathologic findings was 32.2%.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Adenomyosis · Endometrial hyperplasia · Leiomyoma

Abstract

Background/Aim: Benign myometrial lesions are frequently found in pathologic specimens of hysterectomies. High rates of coexistence of these lesions with endometrial cancer have also been reported. Our aim was to evaluate the effect of myometrial lesions on the consistency of diagnoses between endometrial sampling results and final hysterectomy findings in patients with endometrial hyperplasia (EH) before hysterectomy. Methods: Two hundred seventeen patients who were diagnosed as having EH via endometrial sampling and underwent hysterectomy within three months were included in this retrospective cohort study. The patients’ preoperative and postoperative pathologic findings were compared, and discordant results were defined to be either overdiagnosed or underdiagnosed. Results: The overall diagnostic concordance between the endometrial sampling results and the final hysterectomy pathologic findings was 32.2%. The rate of concurrent endometrial carcinoma (EC) among all EH was 22.1%. The discordance between preoperative endometrial sampling and final hysterectomy specimen results was evaluated, and patients with underdiagnosis were older (60.5 years, P

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Cite This Article

TAŞGÖZ, F. N., KENDER, N. (2022). Do myometrial lesions affect the discrepancy of pathological findings in women with endometrial hyperplasia?. Journal of Surgery and Medicine, Cilt: 6 - Sayı: 5, 557–560. https://ajindex.com/articles/779652

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References (14)

  1. Kadirogullari P, Atalay CR, Ozdemir O, Sari ME. Prevalence of co-existing endometrial carcinoma in patients with preoperative diagnosis of endometrial hyperplasia. J Clin Diagn Res. 2015;9(10):Qc10–4
  2. Sccully RE, Bonfiglio TA, Kurman RJ. Histological typing of female genital tumors: international histological classification of tumors. 2nd ed. Springer-Verlag, New York 1994. p.13
  3. Sobczuk K, Sobczuk A. New classification system of endometrial hyperplasia WHO 2014 and its clinical implications. Menopause Rev. 2017;16(3):107–11
  4. Rakha E, Wong SC, Soomro I, Chaudry Z, Sharma A, Deen S, et al. Clinical outcome of atypical endometrial hyperplasia diagnosed on an endometrial biopsy: Institutional experience and review of literature. Am J Surg Pathol. 2012;36:1683–90
  5. Trimble CL, Kauderer J, Zaino R, Silverberg S, Lim PC, Burke JJ. Concurrent endometrial carcinoma in women with a biopsy diagnosis of atypical endometrial hyperplasia: A Gynecologic Oncology Group study. Cancer. 2006;106:812–9
  6. Kurman RJ, Norris HJ. Evaluation of criteria for distinguishing atypical endometrial hyperplasia from well-differentiated carcinoma. Cancer. 1982;49:2547-59
  7. Giannella L, Delli Carpini G, Sopracordevole F, Papiccio M, Serri M, Giorda G, et al. Atypical Endometrial Hyperplasia and Unexpected Cancers at Final Histology: A Study on Endometrial Sampling Methods and Risk Factors. Diagnostics (Basel). 2020;13:10(7):474
  8. Hwang WY, Suh DH, Kim K, No JH, Kim YB. Aspiration biopsy versus dilatation and curettage for endometrial hyperplasia prior to hysterectomy. Diagn Pathol. 2021;14;16(1):7
  9. Erdem B, Aşıcıoğlu O, Seyhan NA, Peker N, Ülker V, Akbayır Ö. Can concurrent high-risk endometrial carcinoma occur with atypical endometrial hyperplasia? Int J Surg. 2018;53:350-3
  10. Garcia, L. Isaacson K. Adenomyosis: review of the literature. J Minim Invasive Gynecol. 2011;18:428–37
  11. Pavone D, Clemenza S, Sorbi F, Fambrini M, Petraglia F. Epidemiology and Risk Factors of Uterine Fibroids. Best Pract Res Clin Obstet Gynaecol. 2018;46:3-11
  12. Mao X, Zheng W, Mao W. Malignant changes in adenomyosis in patients with endometrial adenocarcinoma: A case series. Medicine 2017;.96(43):e8336
  13. Raffone A, Seracchioli R, Raimondo D, Maletta M, Travaglino A, Raimondo I, et al. Prevalence of adenomyosis in endometrial cancer patients: a systematic review and meta-analysis. Arch Gynecol Obstet. 2021;303(1):47-53
  14. Johnatty SE, Stewart CJR, Smith D, Nguyen A, O' Dwyer J,