Results: The monthly treatment cost per patient was higher during the 16th week, 1st year, and 3rd year (€411.80±190.84, €409.7±211.57, €404.2±157.30 respectively) when compared with the pre-treatment period (€107.91±48.62) (p
📌 3 Key Takeaways
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Objective & Hypothesis:Aim: The present study aims to reveal direct cost analysis of patients with severe allergic asthma receiving omalizumab treatment.
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Key Findings & Data:Material and Methods: Twenty-two adults with severe allergic asthma who were treated with omalizumab and were routinely checked on the 16th week, 1st year, and 3rd year of treatment were included in the study.
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Conclusion & Impact:Results: The monthly treatment cost per patient was higher during the 16th week, 1st year, and 3rd year (€411.80±190.84, €409.7±211.57, €404.2±157.30 respectively) when compared with the pre-treatment period (€107.91±48.62) (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Asthma management · severe asthma · cost analysis
Abstract
Aim: The present study aims to reveal direct cost analysis of patients with severe allergic asthma receiving omalizumab treatment. Material and Methods: Twenty-two adults with severe allergic asthma who were treated with omalizumab and were routinely checked on the 16th week, 1st year, and 3rd year of treatment were included in the study. Clinical and demographic features of subjects were retrospectively documented before and after omalizumab treatment as well as pharmaceutical, emergency and hospital costs. Results: The monthly treatment cost per patient was higher during the 16th week, 1st year, and 3rd year (€411.80±190.84, €409.7±211.57, €404.2±157.30 respectively) when compared with the pre-treatment period (€107.91±48.62) (p
ATEŞ, H., AKSU, K., ÖZDEDEOĞLU, Ö., AKDOĞAN, B. B., KALKAN, İ. K., KÖYCÜ, G., ONER, F. (2021). Direct cost analysis for patients with severe asthma receiving omalizumab treatment. Journal of Health Sciences and Medicine, Cilt: 4 - Sayı: 5, 735–740. https://ajindex.com/articles/776852
Beasley R, of Asthma TIS. Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC. The Lancet 1998; 351: 1225-32.
Şekerel BE, Türktaş H, Bavbek S, Öksüz E, Malhan S. Economic burden of pediatric asthma in Turkey: A Cost of Illness Study from payer perspective. Turk Thorac J 2020; 21: 248. D’Amato G, Vitale C, Molino A, et al. Asthma-related deaths. Multidiscip Respir Med 2016; 11: 37. Pakhale S, Mulpuru S, Boyd M. Optimal management of severe/refractory asthma. Clin Med Insights Circ Respir Pulm Med 2011; 5: 37-47.
Adams RJ, Smith BJ, Ruffin RE. Factors associated with hospital admissions and repeat emergency department visits for adults with asthma. Thorax 2000; 55: 566-73.
Bavbek S, Malhan S, Mungan D, et al. Economic burden of severe asthma in Turkey: a cost of illness study from payer perspective. Eur Ann Allergy Clin Immunol 2021; 53: 128-37.
Çelik GE, Bavbek S, Paşaoğlu G, et al. Direct medical cost of asthma in Ankara, Turkey. Respiration 2004; 71: 587-93.
Bavbek S, Mungan D, Türktaş H, et al. A cost-of-illness study estimating the direct cost per asthma exacerbation in Turkey. Respir Med 2011; 105: 541-8. Schulman ES. Development of a monoclonal anti-immunoglobulin E antibody (omalizumab) for the treatment of allergic respiratory disorders. Am J Respir Crit Care Med 2001; 164: 6-11.
Lai T, Wang S, Xu Z, et al. Long-term efficacy and safety of omalizumab in patients with persistent uncontrolled allergic asthma: a systematic review and meta-analysis. Sci Rep 2015; 5: 1-10.
Bousquet J, Cabrera P, Berkman N, et al. The effect of treatment with omalizumab, an anti‐IgE antibody, on asthma exacerbations and emergency medical visits in patients with severe persistent asthma. Allergy 2005; 60: 302-8.
Chipps B, Buhl R, Beeh K-M, et al. Improvement in quality of life with omalizumab in patients with severe allergic asthma. Curr Med Res Opin 2006; 22: 2201-8.
Korn S, Thielen A, Seyfried S, et al. Omalizumab in patients with severe persistent allergic asthma in a real-life setting in Germany. Respir Med 2009; 103: 1725-31.
Bavbek S, Aydın O, Kepil SÖ, et al. Therapy with omalizumab in patients with severe persistent allergic asthma: a real life data in Turkey. Tuberk Toraks 2010; 58: 425-34.
Yorgancıoğlu A, Öner Erkekol F, Mungan D, et al. Long-Term omalizumab treatment: a multicenter, real-life, 5-year trial. Int Arch Allergy Immunol 2018; 176: 225-33.
Tadrous M, Khuu W, Lebovic G, et al. Real-world healt