Journals / Journal of Health Sciences and Medicine / 2022 / Cilt: 5 - Sayı: 1

Hyperlipidemia in Post-COVID patients; a unique observational follow-up study on lipid levels in post-COVID patients

Pages
220–226
Publication Date
2022-01-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Total cholesterol, LDL-C, HDL-C, and triglyceride levels on follow-up were significantly higher than those levels on the admission day (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: Alterations in plasma lipid levels have been shown to be correlated with the severity of infections due to various pathogens such as bacteria, viruses.
📊
Key Findings & Data:In this study, we aimed to evaluate the lipid metabolism changes associated with disease severity and prognosis in hospitalized COVID-19 patients during and after (post-COVID) the disease.
💡
Conclusion & Impact:Total cholesterol, LDL-C, HDL-C, and triglyceride levels on follow-up were significantly higher than those levels on the admission day (p
🔬Design:Research Article
📍Scope:2020 Verileri
⚙️Variables:COVID-19 · dyslipidemia · hyperlipidemia

Abstract

Aim: Alterations in plasma lipid levels have been shown to be correlated with the severity of infections due to various pathogens such as bacteria, viruses. In this study, we aimed to evaluate the lipid metabolism changes associated with disease severity and prognosis in hospitalized COVID-19 patients during and after (post-COVID) the disease. Material and Method: Patients who were hospitalized in the COVID-19 wards between April 02, 2020, and November 20, 2020 and were then evaluated in the follow-up outpatient clinic were retrospectively searched. Results: Lipid levels were present at the admission and follow-up for 95 patients. The mean (S.D) age was 48.49 (16.4), and 49(51.6%) were male. The mean (S.D) day between the admission and the first visit in the COVID-19 follow-up outpatient clinic was 27.8 (12.8). LDL-C (p=0.044), and HDL-C (p=0.004) levels were significantly lower in the severely ill group at the admission. Total cholesterol, LDL-C, HDL-C, and triglyceride levels on follow-up were significantly higher than those levels on the admission day (p

🔖

Cite This Article

UYAROĞLU, O. A., ÖZDEDE, M., BAŞARAN, N. Ç., KÖYLÜ, B., SAHİN, T. K., ÖZIŞIK, L., TANRIÖVER, M. D., GÜVEN, G. S. (2022). Hyperlipidemia in Post-COVID patients; a unique observational follow-up study on lipid levels in post-COVID patients. Journal of Health Sciences and Medicine, Cilt: 5 - Sayı: 1, 220–226. https://ajindex.com/articles/776679

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (10)

  1. Feingold KR, Grunfeld C. The Effect of Inflammation and Infection on Lipids and Lipoproteins. In: Feingold KR, Anawalt B, Boyce A, Chrousos G, et al. (eds). 2019 Jan 8. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-.
  2. Qin C, Minghan H, Ziwen Z, Yukun L. Alteration of lipid profile and value of lipids in the prediction of the length of hospital stay in COVID-19 pneumonia patients. Food Sci Nutr 2020; 8: 6144-52.
  3. Alvarez C, Ramos A. Lipids, lipoproteins, and apoproteins in serum during infection. Clin Chem 1986; 32: 142–5.
  4. Filippas-Ntekouan S, Liberopoulos E, Elisaf M. Lipid testing in infectious diseases: possible role in diagnosis and prognosis. Infection 2017; 45: 575-588.
  5. Grion CM, Cardoso LT, Perazolo TF, et al. Lipoproteins and CETP levels as risk factors for severe sepsis in hospitalized patients. Eur J Clin Invest 2010; 40: 330-8.
  6. Li Y, Zhang Y, Lu R, et al. Lipid metabolism changes in patients with severe COVID-19. Clin Chim Acta 2021; 517: 66-73.
  7. Henry BM, Szergyuk I, de Oliveira MHS, et al. Alterations in the lipid profile associate with a dysregulated inflammatory, prothrombotic, anti-fibrinolytic state and development of severe acute kidney injury in coronavirus disease 2019 (COVID-19): A study from Cincinnati, USA. Diabetes Metab Syndr 2021; 15: 863-8.
  8. Hu X, Chen D, Wu L, He G, Ye W. Declined serum high density lipoprotein cholesterol is associated with the severity of COVID-19 infection. Clin Chim Acta 2020; 510: 105-10.
  9. Wang G, Zhang Q, Zhao X, et al. Low high-density lipoprotein level is correlated with the severity of COVID-19 patients: an observational study. Lipids Health Dis 2020; 19: 204. Masana L, Correig E, Ibarretxe D, et al; STACOV-XULA research group. Low HDL and high triglycerides predict COVID-19 severity. Sci Rep 2021; 11: 7217. Bai Y, Huang W, Li Y, et al. Lipidomic alteration of plasma in cured COVID-19 patients using ultra high-performance liquid chromatography with high-resolution mass spectrometry. Biosci Rep 2021; 41: BSR20204305. Li G, Du L, Cao X, et al. Follow-up study on serum cholesterol profiles and potential sequelae in recovered COVID-19 patients. BMC Infect Dis 2021; 21: 299. World Health Organization. Clinical management of severe acute respiratory infection (SARI) when COVID-19 disease is suspected: interim guidance, 13 March 2020. World Health Organization. [Accessed 14 April 2020]. URL: https://apps.who.int/iris/handle/10665/331446.
  10. Fessler MB, Summer RS. Surfactant lipids at the host-enviro