SavedAdd your journal

Journals / Journal of Health Sciences and Medicine / 2022 / Cilt: 5 - Sayı: 1

Effects of contrast medium exposure on urine albumin/creatinine ratio

Sanem KAYHAN
Fatih KİVRAKOGLU
Aysenur Miray YARLIOGLU
Mercan TAŞTEMUR
İbrahim AKDAĞ
Pages
49–53
Publication Date
2022-01-17
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

When the patients were evaluated for the albuminuria level before the procedure, it has been seen that 73 patients (70.9%) had an Alb/Cr ratio of

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: Albuminuria is a direct consequence of renal glomerular injury and increases with glomerular dysfunction.
📊
Key Findings & Data:Spot urine albumin/creatinine (Alb/Cr) ratio is a reasonable surrogate for 24-hour urine albumin excretion rate and certainly not without limitations.
💡
Conclusion & Impact:When the patients were evaluated for the albuminuria level before the procedure, it has been seen that 73 patients (70.9%) had an Alb/Cr ratio of
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Contrast medium · urine albumin/creatinine ratio · microalbuminuria

Abstract

Aim: Albuminuria is a direct consequence of renal glomerular injury and increases with glomerular dysfunction. Spot urine albumin/creatinine (Alb/Cr) ratio is a reasonable surrogate for 24-hour urine albumin excretion rate and certainly not without limitations. It is known that renal function can be affected following contrast agent administration. The aim of our study is to assess the changes in Alb/Cr ratio in spot urine before and after contrast agents in patients undergoing computed tomography (CT) scanning. Material and Method: The present study included 103 hospitalized patients aged between 18 and 75 years, who underwent contrast-enhanced CT scanning for any reason and did not develop contrast-induced nephropathy (CIN). We compared the values of Alb/Cr ratio at the 6th, 12th, 24th, 48th, and 72nd hours after the procedure (post-procedure time) with the values at pre-procedure time. Results: The median age of the patients were 61 years. It has been observed that there is no significant increased in microalbuminuria after the use of contrast media. When the patients were evaluated for the albuminuria level before the procedure, it has been seen that 73 patients (70.9%) had an Alb/Cr ratio of

🔖

Cite This Article

KAYHAN, S., KİVRAKOGLU, F., YARLIOGLU, A. M., TAŞTEMUR, M., AKDAĞ, İ. (2022). Effects of contrast medium exposure on urine albumin/creatinine ratio. Journal of Health Sciences and Medicine, Cilt: 5 - Sayı: 1, 49–53. https://ajindex.com/articles/776643

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (12)

  1. Andreucci M, Faga T, Pisani A, Sabbatini M, Russo D, Michael A. Prevention of contrast-induced nephropathy through a knowledge of its pathogenesis and risk factors. ScientificWorldJournal 2014; 2014: 823169. Deek H, Newton P, Sheerin N, Noureddine S, Davidson PM. Contrast media induced nephropathy: a literature review of the available evidence and recommendations for practice. Aus Crit Care 2014; 27: 166-71. Stacul F, van der Molen AJ, Reimer P, et al. Contrast induced nephropathy: updated ESUR Contrast Media Safety Committee guidelines. Eur Radiol 2011; 21: 2527-41.
  2. Katsiki N, Athyros VG, Karagiannis A, Mikhailidis DP. Contrast-Induced Nephropathy: An "All or None" Phenomenon? Angiology 2015; 66: 508-13.
  3. Karadeniz M, Kandemir H, Sarak T, Alp Ç. Akut koroner sendromda perkütan koroner girişim yapılan hastalarda kontrast nefropati prevalansı. J Health Sci Med 2018; 1: 34-9.
  4. Ronco F, Tarantini G, McCullough PA. Contrast induced acute kidney injury in interventional cardiology: an update and key guidance for clinicians. Rev Cardiovasc Med 2020; 2: 9-23.
  5. Okoye O, Ikubor J, Okosun RE. Biochemical changes associated with intravenous use of contrast media. Tropical J Nephrol 2015; 10: 73-8.
  6. Seeliger E, Persson PB. Kidney damage by iodinated contrast media. Acta Physiol (Oxf.) 2019; 227: e13259. Lippi G, Daves M, Mattiuzzi C. Interference of medical contrast media on laboratory testing. Biochemia Medica 2014; 24: 80-8.
  7. Keane WF, Eknoyan G. Proteinuria, albuminuria, risk, assessment, detection, elimination (PARADE): a position paper of the National Kidney Foundation. Am J Kidney Dis 1999; 33: 1004-10. Thorp ML. Diabetic nephropathy: common questions. Am Fam Physician 2005; 72: 96-9.
  8. Simerville JA, Maxted WC, Pahira JJ. Urinalysis: a comprehensive review. Am Fam Physician 2005; 71: 1153-62.
  9. Levin A, Pate GE, Shalansky S, et al. N-acetylcysteine reduces urinary albumin excretion following contrast administration: evidence of biological effect. Nephrol Dial Transplant 2007; 22: 2520-4.
  10. Nicot GS, Merle LJ, Charmes JP, et al. Transient glomerular proteinuria, enzymuria, and nephrotoxic reaction induced by radiocontrast media. Jama 1984; 252: 2432-4.
  11. Tumlin JA, Wang A, Murray PT, Mathur VS. Fenoldopam mesylate blocks reductions in renal plasma flow after radiocontrast dye infusion: a pilot trial in the prevention of contrast nephropathy. Am Heart J 2002; 143: 894-903.
  12. Inker LA, Astor BC, Fox CH, et al. KDOQI US commentary on the 2012 KDIGO clinical practice guideline for