Journals / Gazi Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi / 2022 / Cilt: 4 - Sayı: 2

Pharmacologically Active Molecules Bearing the Pyridazinone Ring as Main Scaffold

Pages
61–79
Publication Date
2022-08-31
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, some of the antibacterial and antifungal, analgesic and anti-inflammatory, anticancer, cardiovascular and anticholinesterase compounds with pyridazinone structure are mentioned.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Pyridazines are organic compounds in which benzene has nitrogen atoms instead of two carbon atoms.
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Key Findings & Data:The pyridazine structure is one of the heteroaromatic rings that can be developed for drug design.
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Conclusion & Impact:In this review, some of the antibacterial and antifungal, analgesic and anti-inflammatory, anticancer, cardiovascular and anticholinesterase compounds with pyridazinone structure are mentioned.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:pyridazine · 3(2H)-pyridazinone · heterocyclic

Abstract

Pyridazines are organic compounds in which benzene has nitrogen atoms instead of two carbon atoms. The pyridazine structure is one of the heteroaromatic rings that can be developed for drug design. Pyridazinone analogues are found in the structure of drugs with different activities. This core is of interest to medicinal chemists because of its diverse pharmacological activities. In this review, some of the antibacterial and antifungal, analgesic and anti-inflammatory, anticancer, cardiovascular and anticholinesterase compounds with pyridazinone structure are mentioned.

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Cite This Article

ÖZDEMİR, Z., ALAGÖZ, M. A., ARSLAN, G., ÖZÇELİK, A. B. (2022). Pharmacologically Active Molecules Bearing the Pyridazinone Ring as Main Scaffold. Gazi Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, Cilt: 4 - Sayı: 2, 61–79. https://ajindex.com/articles/760582

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