Journals / European Journal of Research in Dentistry / 2022 / Cilt: 6 - Sayı: 1

Use of Botulinum Toxin In The Treatment of Temporomandibular Disorders

Temporomandibular Rahatsızlıkların Tedavisinde Botulinum Toksin Kullanımı

Pages
46–57
Publication Date
2022-06-22
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, the place of BoNT injection in TMD treatment, its application technique and its effect on symptoms are evaluated in the light of literature.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Temporomandibular disorder (TMD) is a term used to describe disorders that involve the temporomandibular joint, the masticatory muscles and associated structures.
📊
Key Findings & Data:Patients with TMD have symptoms such as tenderness and pain in the joints and masticatory muscles, limitation in mouth opening, and joint sounds.
💡
Conclusion & Impact:In this review, the place of BoNT injection in TMD treatment, its application technique and its effect on symptoms are evaluated in the light of literature.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:temporomandibular rahatsızlıklar · Botulinum Toksin · Bruksizm

Abstract

Temporomandibular disorder (TMD) is a term used to describe disorders that involve the temporomandibular joint, the masticatory muscles and associated structures. Patients with TMD have symptoms such as tenderness and pain in the joints and masticatory muscles, limitation in mouth opening, and joint sounds. TMD treatment usually requires a multidisciplinary approach and reversible conservative treatment options should be the first choice. Botulinum toxin (BoNT) injection, which is one of these treatment options, is used in many areas of dentistry, as well as in various TMD treatments. BoNT is a neurotoxin that inhibits the release of acetylcholine at the neuromuscular junction and inhibits contraction of the target muscle. In the treatment of TMD, BoNT is applied to reduce muscle tension that causes various temporomandibular diseases and symptoms. In this review, the place of BoNT injection in TMD treatment, its application technique and its effect on symptoms are evaluated in the light of literature.

Özet

Temporomandibular rahatsızlıklar (TMR), temporomandibular eklemler, çiğneme kasları ve tüm ilişkili dokuları kapsayan bir grup rahatsızlık olarak tanımlanmıştır. TMR’si olan hastalarda eklem ve çiğneme kaslarında hassasiyet ve ağrı, ağız açmada kısıtlılık, eklem sesleri gibi semptomlar görülür. TMR tedavisi genellikle multidisipliner yaklaşım gerektirir. Tedavide öncelik geri dönüşümsüz etkileri olmayan konservatif tedavi seçenekleri olmalıdır. Günümüzde bu tedavi seçeneklerinden biri olan Botulinum toksin (BoNT) uygulanması diş hekimliğinin birçok alanıyla birlikte çeşitli TMR'lerin tedavisinde de kullanılmaktadır. BoNT, nöromusküler kavşakta asetilkolin salınımını inhibe eden ve hedef kasta kontraksiyonu engelleyen bir nörotoksindir. TMR tedavisinde BoNT, çeşitli temporomandibular hastalık ve semptomlara yol açan kas gerginliğini azaltmak amacıyla uygulanmaktadır. Bu derlemede, BoNT’in TMR tedavisindeki yeri, uygulama tekniği ve semptomlar üzerindeki etkisi literatürdeki çalışmalar ışığında değerlendirilmektedir.

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Cite This Article

ÖZEL, H. B. U., ASLAN, Y. U., SANCAKLI, E. (2022). Use of Botulinum Toxin In The Treatment of Temporomandibular Disorders. European Journal of Research in Dentistry, Cilt: 6 - Sayı: 1, 46–57. https://ajindex.com/articles/757844

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References (12)

  1. Altaweel AA, Elsayed SAH, Baı̇omy AABA, Abdelsadek SE, Hyder AA. Extraoral Versus Intraoral Botulinum Toxin Type A Injection for Management of Temporomandibular Joint Disc Displacement With Reduction. J Craniofac Surg, 2019; 30(7): 2149–53
  2. Aquilina P, Vickers R, McKellar G. Reduction of a chronic bilateral temporomandibular joint dislocation with intermaxillary fixation and botulinum toxin A. Br J Oral Maxillofac Surg. 2004; 42: 272-273
  3. Arinci A, Güven E, Yazar M, Başaran K, Keklik B. Effect of injection of botulinum toxin on lateral pterygoid muscle used together with the arthroscopy in patients with anterior disk displacement of the temporomandibular joint. Kulak Burun Bogaz Ihtis Derg. 2009;19(3):122-9
  4. Arnon SS, Schechter R, Inglesby TV, Henderson DA, Bartlett JG, Ascher MS, Eitzen E, Fine AD, Hauer J, Layton M, Lillibridge S, Osterholm MT, O'Toole T, Parker G, Perl TM, Russell PK, Swerdlow DL, Tonat K. Working Group on Civilian Biodefense. Botulinum toxin as a biological weapon: medical and public health management. JAMA. 2001;285(8):1059-70
  5. Aurora SK, Dodick DW, Turkel CC, DeGryse RE, Silberstein SD, Lipton RB, Diener HC, Brin MF; PREEMPT 1 Chronic Migraine Study Group. OnabotulinumtoxinA for treatment of chronic migraine: results from the double-blind, randomized, placebo-controlled phase of the PREEMPT 1 trial. Cephalalgia. 2010;30(7):793-803
  6. Bakheı̇t, AM. The possible adverse effects of intramuscular botulinum toxin injections and their management. Current Drug Safety. 2006; 1(3): 271–9
  7. Bakke M, Møller E, Werdelin LM, Dalager T, Kitai N, Kreiborg S. Treatment of severe temporomandibular joint clicking with botulinum toxin in the lateral pterygoid muscle in two cases of anterior disc displacement. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005; 100: 693-700
  8. Barnes M. Botulinum toxin- mechanisms of action and clinical use in spasticity. J Rehabil Med. 2003; 35(0): 56–9
  9. Baumann L, Black L. Botulinum toxin type B (Myobloc). Dermatol Surg. 2003; 29(5): 496–500
  10. Bhogal PS, Hutton A, Monaghan A. Review of the current uses of Botox for dentally-related procedures. Dental Update. 2006; 33(3): 165-8
  11. Binz T, Blasi J, Yamasaki S, Baumeister A, Link E, Südhof TC, Jahn R, Niemann H. Proteolysis of SNAP-25 by types E and A botulinal neurotoxins. J Biol Chem. 1994; 269(3): 1617-20
  12. Bottemly I. Comparing Neuretoxins: Botox, Dysport, Jeuveau and Xeomin. Erişim Tarihi (14.3.2022) https://aedit.com/aedition/comp