Journals / The Turkish Journal of Ear Nose and Throat / 2003 / Cilt: 11 - Sayı: 6

A case of granulocytic sarcoma during complete remission of acute myeloid leukemia with multiple masses involving the larynx and nasopharynx

Akut miyeloid löseminin tam remisyon döneminde ortaya çıkan ve multipl kitleler ile birlikte larenks ve nazofarenksi eşzamanlı tutan granülositik sarkom olgusu

Pages
183–188
Publication Date
2003-12-24
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Hovvever, the patient died due to a pulmonary infeetion on the 17th day of chemotherapy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A thirty-seven-year-old male patient presented with dysphagia and hoarseness six months after complete remis­ sion of acute myeloid leukemia AML-MQ , which had been treated with chemotherapy.
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Key Findings & Data:Physical examination revealed left vocal cord paralysis and involvement of the 9th, 10th, and 12th cranial nerves.
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Conclusion & Impact:Hovvever, the patient died due to a pulmonary infeetion on the 17th day of chemotherapy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Antineoplastik birleflik kemoterapi protokolü · larenks neoplazileri · lösemi

Abstract

A thirty-seven-year-old male patient presented with dysphagia and hoarseness six months after complete remis­ sion of acute myeloid leukemia AML-MQ , which had been treated with chemotherapy. Physical examination revealed left vocal cord paralysis and involvement of the 9th, 10th, and 12th cranial nerves. Sagittal and axial magnetic resonance seans of the nasopharynx and neck shovved a mass in the left retropharyngeal and periverte- bral regions, 6x4 cm in size; another mass in the left val- lecula, and infiltration of the right preepiglottic tissue by another mass of 2 cm. There was no bone marrovv involvement. A diagnosis of granulocytic sarcoma vvithout leukemia relapse was made and the FLAG-lda regimen was administered, after which partial regression of the masses was observed. Hovvever, the patient died due to a pulmonary infeetion on the 17th day of chemotherapy.

Özet

Akut miyeloid lösemi AML-M0 tanısıyla uygulanan ke- moterapiden sonra komplet remisyona giren 37 yaflın- daki erkek hastada, remisyon sonrası altıncı ayda dis- faji ve ses kısıklığı flikayetleri görüldü. Fizik muayene- sinde sol vokal kord paralizisi ve 9, 10 ve 12. kranyal si- nir tutulumu saptandı. Nazofarenks ve boynun sagittal ve aksiyal manyetik rezonans kesitlerinde, sol retrofa- renjeal ve perivertebral bölgede yerleflim gösteren 6x4 cm boyutlarında bir kitle, sol vallekulada baflka kitle ve sağ preepiglottik dokuda infiltrasyona yol açan 2 cm büyüklüğünde baflka bir kitle belirlendi. Kemik iliği tutu- lumu saptanmadı. Lösemi nüksü olmaksızın granülosi- tik sarkom tanısıyla FLAG-Ida rejimi uygulanmasından sonra kitlelerde kısmi gerileme görülmesine rağmen, kemoterapinin 17. gününde hasta pulmoner enfeksiyon nedeniyle yaflamını yitirdi

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Cite This Article

ALİ, R., ÖZÇELİK, T., ÖZKALEMKAŞ, F., ÖZKOCAMAN, V., COŞKUN, H. H., ERİŞEN, L., FİLİZ, G. (2003). A case of granulocytic sarcoma during complete remission of acute myeloid leukemia with multiple masses involving the larynx and nasopharynx. The Turkish Journal of Ear Nose and Throat, Cilt: 11 - Sayı: 6, 183–188. https://ajindex.com/articles/727265

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