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Journals / Adnan Menderes Üniversitesi Sağlık Bilimleri Fakültesi Dergisi / 2021 / Cilt: 5 - Sayı: 3

Exercise-induced Weight Loss and Glutathione S-Transferase

Egzersize Bağlı Kilo Kaybı ve Glutatyon S-Transferaz

Adem KESKİN
Aslıhan BÜYÜKÖZTÜRK KARUL
Pages
575–582
Publication Date
2021-09-30
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There was an inverse correlation between exercise-induced weight loss and Glutathione S-Transferase enzyme activity.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: In this study, it was aimed to investigate the effect of weight loss observed in exercised rats on Glutathione S-Transferase enzyme activity.Methods: The rats were exercised for 10 days.
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Key Findings & Data:It was observed that the weight loss in the melatonin and niacin group was significant, considering body weight (p<0.001).
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Conclusion & Impact:There was an inverse correlation between exercise-induced weight loss and Glutathione S-Transferase enzyme activity.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Egzersiz · Kilo Kaybı · Glutatyon S-Transferaz

Abstract

Objective: In this study, it was aimed to investigate the effect of weight loss observed in exercised rats on Glutathione S-Transferase enzyme activity.Methods: The rats were exercised for 10 days. Melatonin and niacin were given to one group in order to create a difference in weight loss between groups. The rats were weighed throughout the study. Intracardiac blood samples were taken, one day after the last exercise. Glutathione S-Transferase enzyme activity was measured.Results: Weight loss was observed in the groups. It was observed that the weight loss in the melatonin and niacin group was significant, considering body weight (p<0.001). Glutathione S-Transferase enzyme activity of this group with higher weight loss was observed to be lower than the other group (p<0.001). There was an inverse correlation between the weight loss observed in the groups and the analyzed Glutathione S-Transferase enzyme activity levels (p<0.001). Conclusion: Approximately 4% weight loss occurred in one group. There was an inverse correlation between exercise-induced weight loss and Glutathione S-Transferase enzyme activity.

Özet

Amaç: Bu çalışmada, egzersiz yaptırılan ratlarda gözlenen kilo kaybının, Glutatyon S-Transferaz enzim aktivitesi üzerine etkisinin araştırılması amaçlanmıştır.Yöntem: Ratlara 10 günlük egzersiz yaptırıldı. Gruplar arası kilo kaybı farkı oluşması amacıyla bir gruba melatonin ve niasin verildi. Çalışma boyunca ratlar tartıldı. Son egzersizden bir gün sonra intrakardiyak kan örnekleri alındı. Glutatyon S-Transferaz enzim aktivitesi ölçüldü. Bulgular: Gruplarda kilo kaybı gözlendi. Vücut ağırlığı dikkate alındığında, melatonin ve niasin verilen grupta oluşan kilo kaybının anlamlı olduğu gözlendi (p<0.001). Kilo kaybı daha yüksek olan bu grubun Glutatyon S-Transferaz enzim aktivitesi, diğer gruptan daha düşük olduğu gözlendi (p<0.001). Gruplarda gözlenen kilo kaybı ile analizi yapılan Glutatyon S-Transferaz enzim aktivite düzeyleri arasında zıt yönlü korelasyon olduğu gözlendi (p<0.001).Sonuç: Bir grupta yaklaşık %4 düzeyinde kilo kaybı oluştu. Egzersize bağlı kilo kaybı ile Glutatyon S-Transferaz enzim aktivitesi arasında zıt yönde bir korelasyon olduğu saptandı.

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Cite This Article

KESKİN, A., KARUL, A. B. (2021). Exercise-induced Weight Loss and Glutathione S-Transferase. Adnan Menderes Üniversitesi Sağlık Bilimleri Fakültesi Dergisi, Cilt: 5 - Sayı: 3, 575–582. https://ajindex.com/articles/725449

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