SavedAdd your journal

Journals / Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2022 / Cilt: 55 - Sayı: 2

Metabolic status is not related to dietary acid load in polycystic ovary syndrome

Tülay OMMA
Fatmanur Hümeyra ZENGİN
Süheyla AYDOĞMUŞ
Cavit ÇULHA
Pages
111–115
Publication Date
2022-08-31
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results:We concluded no statistically significant difference between the groups by NEAP (p=0.569) and PRAL (p=0.969).Patients with PCOS had higher fasting insulin levels and HOMA-IR (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim:Women with polycystic ovary syndrome (PCOS) are at high risk for obesity-related disorders, insulin resistance (IR), and metabolic syndrome (MS).
📊
Key Findings & Data:Material and Method: This study included 46 newly diagnosed PCOS patients and 46 healthy individuals with matched age, sex, and BMI.
💡
Conclusion & Impact:Results:We concluded no statistically significant difference between the groups by NEAP (p=0.569) and PRAL (p=0.969).Patients with PCOS had higher fasting insulin levels and HOMA-IR (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Polycystic ovary sydrome · insulin resistance · dietary acid load

Abstract

Aim:Women with polycystic ovary syndrome (PCOS) are at high risk for obesity-related disorders, insulin resistance (IR), and metabolic syndrome (MS). Adopting potent approaches to diet enhances cardiometabolic risk profile and reproductive function. Different types of diets have provided conflicting results so far. We aimed to investigate whether dietary acid load (DAL) contributed to the metabolic process in PCOS. Material and Method: This study included 46 newly diagnosed PCOS patients and 46 healthy individuals with matched age, sex, and BMI. Clinical, anthropometric, and biochemical measurements were obtained. We extracted net endogenous acid production (NEAP) and potential renal acid load (PRAL) scores from 24-hour dietary data recorded on a nutrient database program for three days (BeBiS software program). Results:We concluded no statistically significant difference between the groups by NEAP (p=0.569) and PRAL (p=0.969).Patients with PCOS had higher fasting insulin levels and HOMA-IR (p

Özet

Aim:Women with polycystic ovary syndrome (PCOS) are at high risk for obesity-related disorders, insulin resistance (IR), and metabolic syndrome (MS). Adopting potent approaches to diet enhances cardiometabolic risk profile and reproductive function. Different types of diets have provided conflicting results so far. We aimed to investigate whether dietary acid load (DAL) contributed to the metabolic process in PCOS. Material and Method: This study included 46 newly diagnosed PCOS patients and 46 healthy individuals with matched age, sex, and BMI. Clinical, anthropometric, and biochemical measurements were obtained. We extracted net endogenous acid production (NEAP) and potential renal acid load (PRAL) scores from 24-hour dietary data recorded on a nutrient database program for three days (BeBiS software program). Results:We concluded no statistically significant difference between the groups by NEAP (p=0.569) and PRAL (p=0.969).Patients with PCOS had higher fasting insulin levels and HOMA-IR (p

🔖

Cite This Article

OMMA, T., ZENGİN, F. H., AYDOĞMUŞ, S., ÇULHA, C. (2022). Metabolic status is not related to dietary acid load in polycystic ovary syndrome. Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 55 - Sayı: 2, 111–115. https://ajindex.com/articles/712590

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (17)

  1. Yildiz BO, Bozdag G, Yapici Z, et al. Prevalence, phenotype and cardiometabolic risk of polycystic ovary syndrome under different diagnostic criteria. Hum Reprod. 2012;27:3067-3073
  2. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod. 2004;19:41-47
  3. Ehrmann DA. Polycystic ovary syndrome. N Engl J Med. 2005;352:1223-1236
  4. Barber TM, Franks S. Adipocyte biology in polycystic ovary syndrome. Mol Cell Endocrinol. 2013;373:68-76
  5. Randeva HS, Tan BK, Weickert MO, et al. Cardiometabolic aspects of the polycystic ovary syndrome. Endocr Rev. 2012;33:812-841
  6. Barber TM, McCarthy MI, Wass JA, et al. Obesity and polycystic ovary syndrome. Clin Endocrinol (Oxf.) 2006;65:137-145
  7. Azziz R, Carmina E, Chen Z, et al. Polycystic ovary syndrome. Nat Rev Dis Primers. 2016;2:16057
  8. Stepto NK, Cassar S, Joham AE, et al. Women with polycystic ovary syndrome have intrinsic insulin resistance on euglycaemic-hyperinsulaemic clamp. Hum Reprod. 2013;28:777-784
  9. Wild RA. Dyslipidemia in PCOS. Steroids. 2012;77:295-299
  10. Teede HJ, Joham AE, Paul E, et al. Longitudinal weight gain in women identified with polycystic ovary syndrome: results of an observational study in young women. Obesity (Silver Spring). 2013;21:1526-1532
  11. Akter S, Eguchi M, Kuwahara K, et al. High dietary acid load is associated with insulin resistance: The Furukawa Nutrition and Health Study. Clin Nutr. 2016;35:453-459
  12. Remer T. Influence of nutrition on acid-base balance--metabolic aspects. Eur J Nutr. 2001;40:214-220
  13. Han E, Kim G, Hong N, et al. Association between dietary acid load and the risk of cardiovascular disease: nationwide surveys (KNHANES 2008-2011). Cardiovasc Diabetol. 2016;15:122
  14. Remer T, Dimitriou T, Manz F. Dietary potential renal acid load and renal net acid excretion in healthy, free-living children and adolescents. Am J Clin Nutr. 2003;77:1255-1260
  15. Abbasalizad Farhangi M, Nikniaz L, Nikniaz Z. Higher dietary acid load potentially increases serum triglyceride and obesity prevalence in adults: An updated systematic review and meta-analysis. PLoS One. 2019;14:e0216547
  16. Akter S, Eguchi M, Kurotani K, et al. High dietary acid load is associated with increased prevalence of hypertension: the Furukawa Nutrition and Health Study. Nutrition. 2015;31:298-303
  17. Kiefte-de Jong JC, Li Y, Chen M, et al. Diet-dependent acid load and type 2 diabetes: pooled results from three p