Journals / The European Research Journal / 2016 / Cilt: 2 - Sayı: 2

Mean platelet volume is increased in patients with chronic hepatitis B

Pages
132–136
Publication Date
2016-07-04
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Therefore, we have investigated the possible association between HBV infection and MPV.

📌 3 Key Takeaways

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Objective & Hypothesis:Hepatitis secondary to infection with the hepatitis B virus (HBV) is one of the most common causes of viral hepatitis worldwide.
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Key Findings & Data:The study group consisted of 50 patients with chronic hepatitis B.
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Conclusion & Impact:Therefore, we have investigated the possible association between HBV infection and MPV.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Platelets · arrhythmia · hepatitis B virus

Abstract

Background. Hepatitis secondary to infection with the hepatitis B virus (HBV) is one of the most common causes of viral hepatitis worldwide. Multiple extrahepatic manifestations of HBV infection have been recognized. However, the effect of HBV infection on the mean platelet volume (MPV) is unknown. The aim of this study was to assess the MPV, an indicator of platelet activation, in patients with chronic hepatitis B. Methods. The study group consisted of 50 patients with chronic hepatitis B. An age, gender, and body mass index-matched control group consisted of 50 healthy volunteers. All patients and control participants underwent echocardiographic examination. We measured the serum MPV values in patients and control participants. Results. Mean platelet volume was significantly higher among patients with HBV when compared with the control group (9.2±2.2 vs 7.1±1.6 fl, respectively; p<0.001). Conclusion. We have shown that MPV was significantly elevated in patients with chronic hepatitis B compared to control participants. According to our knowledge, there has been no previous study of MPV in chronic HBV patients. Therefore, we have investigated the possible association between HBV infection and MPV.

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Cite This Article

DEMİR, C., DEMİR, M. (2016). Mean platelet volume is increased in patients with chronic hepatitis B. The European Research Journal, Cilt: 2 - Sayı: 2, 132–136. https://ajindex.com/articles/704050

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References (9)

  1. Lavanchy D. Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures. J Viral Hepat 2004;11:97-107.
  2. Kwon SY, Lee CH. Epidemiology and prevention of hepatitis B virus infection. Korean J Hepatol 2011;17:87-95. Matsumori A. Symposium on clinical aspects in hepatitis virus infection. 5. Clinical practice of hepatitis: myocardial diseases, nephritis, and vasculitis associated with hepatitis virus. Intern Med 2001;40:182-4.
  3. Rong Q, Huang j, Su E, Li J, Li J, Zhang L, et al. Infection of hepatitis B virus in extrahepatic endothelial tissues mediated by endothelial progenitor cells. Virol J 2007;4:36. Franceschi S, Lise M, Trepo C, Berthillon P, Chuang SC, Nieters A, et al. Infection with hepatitis B and C viruses and risk of lymphoid malignancies in the European Prospective Investigation into Cancer and Nutrition (EPIC). Cancer Epidemiol Biomarkers Prev 2011;20:208-14.
  4. Matsumori A, Ohashi N, Hasegawa K, Sasayama S, Eto T, Imaizumi T, et al. Hepatitis C virüs infection and heart diseases: a multicenter study in Japan. Jpn Circ J 1998;62:389-91.
  5. Amirzadegan A, Davoodi G, Boroumand MA, Darabyan S, Dehkordi MR, Goodarzynejad H. Association between hepatitis B surface antibody seropositivity and coronary artery disease. Indian J Med Sci 2007;61:648-55. Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) Study Group, Weber R, Sabin C, Reiss P, de Wit S, Worm SW, Law M, et al. HBV or HBV coinfections and risk of myocardial infarction in HIV-infected individuals: the D:A:D Cohort Study. Antivir Ther 2010;15:1077-86.
  6. Varol E, Arslan A, Yucel H, Ozaydin M, Erdogan D, Dogan A. Increased mean platelet volume in patients with aortic stenosis. Clin Appl Thromb Hemost 2011;17:E17-20. Varol E, Ozaydin M, Turker Y, Alaca S. Mean platelet volume, an indicator of platelet activation, is increased in patients with mitral stenosis and sinus rhythm. Scand J Clin Lab Invest 2009;69:708-12.
  7. Gulcan M, Varol E, Etli M, Aksoy F, Kayan M. Mean platelet volume is increased in patients with deep vein thrombosis. Clin Appl Thromb Hemost 2012;18:427-30.
  8. Varol E, Akcay S, Icli A, Ozkan E, Erdogan D, Ozaydin M. M. Mean platelet volume in patients with prehypertension and hypertension. Clin Hemorheol Microcirc 2010;45:67-72.
  9. Schiller NB, Shah PM, Crawford M, DeMaria A, Devereux R, Feigenbaum H, et al. Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Co