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Journals / The European Research Journal / 2016 / Cilt: 2 - Sayı: 3

Relation of neutrophil/lymphocyte ratio to resistant hypertension

Necati DAGLİ
Orhan DOGDU
Omer SENARSLAN
Hasan YUCEL
Hakki KAYA
Mahmut AKPEK
Semih ERİTEN
Pages
211–218
Publication Date
2016-11-04
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The N/L ratio, which is cheaply and easily measurable laboratory data, is independently associated with resistant hypertension.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Resistant hypertension has unfavourable effects on cardiovascular and other systems.
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Key Findings & Data:A total of 140 patients were included in the study.
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Conclusion & Impact:The N/L ratio, which is cheaply and easily measurable laboratory data, is independently associated with resistant hypertension.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Resistant hypertension · ambulatory blood pressure monitoring · neutrophil/lymphocyte ratio

Abstract

Objectives. Resistant hypertension has unfavourable effects on cardiovascular and other systems. The aim of this study was to investigate the association of neutrophil/lymphocyte (N/L) ratio and resistant hypertension. Methods. A total of 140 patients were included in the study. Ambulatory 24-hour blood pressure monitoring, transthoracic echocardiography and blood sample analyzing were performed in all patients. There were 60 patients with resistant hypertension group (mean age=55.1±9.7 years) and 80 patients with non-resistant hypertension group (mean age=56.8±14.1 years). Results. Mean neutrophil levels were significantly higher in resistant hypertension group (71.7±6.1% vs. 65.9±5.4%, p<0.001), while lymphocyte levels were significantly higher in non-resistant hypertension group (22±4.7% vs. 17.5±4.1%, p<0.001). N/L ratio was significantly higher in resistant hypertension group (4.3±1.2 vs. 3.1±0.9, p<0.001). In multivariate analysis, diabetes mellitus (odds ratio [OR]=2.857; 95% confidence interval [CI], 1.349-6.053; p=0.006), N/L ratio (OR=2.699; 95% CI, 1.821-4.002; p<0.001) and obesity (OR=3.429; 95% CI, 1.675-7.019; p=0.001) were independent predictors of resistant hypertension. Conclusion. The N/L ratio, which is cheaply and easily measurable laboratory data, is independently associated with resistant hypertension.

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Cite This Article

DAGLİ, N., DOGDU, O., SENARSLAN, O., YUCEL, H., KAYA, H., AKPEK, M., ERİTEN, S. (2016). Relation of neutrophil/lymphocyte ratio to resistant hypertension. The European Research Journal, Cilt: 2 - Sayı: 3, 211–218. https://ajindex.com/articles/704018

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