Journals / Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi / 2018 / Cilt: 9 - Sayı: 4

Histopathological Effects of 2.45 Gigahertz Electromagnetic Radiation on the Kidney, and Protective Effects of Vitamin C

2.45 gigahertz elektromanyetik radyasyonun böbrekteki histopatolojik etkileri ve C vitamininin koruyucu etkisi

Pages
1–5
Publication Date
2018-12-25
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Electromagnetic radiation-induced tubular and glomerular damage in the kidney was almost completely reversed with the administration of vitamin C before electromagnetic radiation exposure.

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Objective & Hypothesis:Objectives: To investigate the effects of electromagnetic radiation (EMR) on the kidneys based on histopathological changes of renal damage, and to investigate the ameliorating effects of vitamin C (ascorbic acid) against EMR-induced renal damage in rats.Materials and Methods: Eighteen female Sprague-Dawley rats were divided into three groups of six rats each.
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Key Findings & Data:Group 1 was the sham group; these rats were kept in their cages without stress or electromagnetic radiation exposure.
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Conclusion & Impact:Conclusion: Electromagnetic radiation-induced tubular and glomerular damage in the kidney was almost completely reversed with the administration of vitamin C before electromagnetic radiation exposure.
🔬Design:Lab & Field Experiment
📍Scope:Comprehensive Sample
⚙️Variables:Antioksidanlar · Askorbik asit · Elektromanyetik radyasyon

Abstract

Objectives: To investigate the effects of electromagnetic radiation (EMR) on the kidneys based on histopathological changes of renal damage, and to investigate the ameliorating effects of vitamin C (ascorbic acid) against EMR-induced renal damage in rats.Materials and Methods: Eighteen female Sprague-Dawley rats were divided into three groups of six rats each. Group 1 was the sham group; these rats were kept in their cages without stress or electromagnetic radiation exposure. Group 2 was exposed to 2.45 gigahertz electromagnetic radiation for 30 days. Group 3 was also exposed to 2.45 gigahertz electromagnetic radiation for 30 days (1 h/day) but received vitamin C 24 hours prior to the first exposure and daily throughout the experiment. All rats underwent nephrectomy with histopathological examination. Results: There were no pathological findings in the sham group. Significant pathological changes were observed in group 2, including tubular and glomerular damage (P<0.05). Interstitial and vascular damage was not significantly different between groups 2 and 3 (P>0.05). Tubular and glomerular damage was less severe in group 3 than in group 2 (P<0.05). There was no significant difference between the sham group and group 3 in terms of tubular, glomerular, interstitial, or vascular damage (P>0.05). Conclusion: Electromagnetic radiation-induced tubular and glomerular damage in the kidney was almost completely reversed with the administration of vitamin C before electromagnetic radiation exposure.

Özet

Amaçlar: Elektromanyetik radyasyonun (EMR) sıçan böbreğinde yol açtığı histopatolojik hasarı ve C vitamininin (askorbik asit) oluşan bu renal hasara karşı iyileştirici etkilerini araştırmak.Gereç ve Yöntemler: On sekiz dişi Sprague-Dawley sıçanı, her biri altı sıçan olmak üzere üç gruba ayrıldı. Grup 1 şam grubuydu; bu sıçanlar herhangi bir stres veya elektromanyetik radyasyona maruz kalmadan kafeslerinde tutuldu. Grup 2, 30 gün boyunca 2.45 gigahertz elektromanyetik radyasyona maruz bırakıldı. Grup 3 de 30 gün boyunca (günde 1 saat) 2.45 gigahertz elektromanyetik radyasyona maruz bırakıldı, ancak ilk maruziyetinden 24 saat önce ve deney boyunca her gün C vitamini verildi. Tüm sıçanlara histopatolojik inceleme için nefrektomi yapıldı. Bulgular: Şam grubunda herhangi bir patolojik değişiklik olmadı. Grup 2’de tübüler ve glomerüler hasarı içeren önemli patolojik değişiklikler izlendi (P<0.05). İnterstisyel ve vasküler hasar açısından grup 2 ve 3’te önemli bir değişiklik izlenmedi (P>0.05). Tübüler ve glomerüler hasar grup 3’te grup 2’ye göre daha az şiddetliydi (P<0.05). Şam grubu ve grup 3 arasında tübüler, glomerüler, interstisyel ve vasküler hasar açısından önemli bir farklılık izlenmedi (P>0.05). Sonuç: Elektromanyetik radyasyonun böbrekte yol açtığı tübüler ve glomerüler hasar, elektromanyetik radyasyon maruziyeti öncesi alınan C vitamini ile neredeyse tamamen normale dönmektedir.

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Cite This Article

BAŞ, E., UÇAR, M., BAŞ, F. Y., YEŞİLOT, Ş., ARMAĞAN, İ., YALÇIN, A. (2018). Histopathological Effects of 2.45 Gigahertz Electromagnetic Radiation on the Kidney, and Protective Effects of Vitamin C. Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi, Cilt: 9 - Sayı: 4, 1–5. https://ajindex.com/articles/702296

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