Journals / Pamukkale Tıp Dergisi / 2022 / Cilt: 15 - Sayı: 2

Investigation of demographic, clinical and radiological findings of cases with intracranial aneurysm: 107 cases, single center experience

İntrakraniyal anevrizmalı olguların demografik, klinik ve radyolojik bulgularının incelenmesi: 107 olgu, tek merkez deneyimi

Pages
205–212
Publication Date
2022-04-01
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We think that early surgery can be used for appropriate treatment becauseof the risk of re-bleeding and the safe fight against vasospasm after surgery.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: It was aimed to retrospectively examine the demographic, clinical-radiological findings of patients withintracranial aneurysm who were hospitalized with the diagnosis of aneurysm and underwent surgical andendovascular treatment, and the relationship between these findings and mortality rates.Material and methods: After diagnosis with cranial computed tomography, the localization of aneurysms wasdetermined by computed tomography angiography or dynamic cerebral angiography, 101 patients underwentstandard open microsurgery, and 7 patients underwent embolization by endovascular surgery.
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Key Findings & Data:Temporary clipswere used for 30 seconds to 4 minutes (average 2 minutes).
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Conclusion & Impact:We think that early surgery can be used for appropriate treatment becauseof the risk of re-bleeding and the safe fight against vasospasm after surgery.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Subaraknoid kanama · anevrizma · demografik özellikler

Abstract

Aim: It was aimed to retrospectively examine the demographic, clinical-radiological findings of patients withintracranial aneurysm who were hospitalized with the diagnosis of aneurysm and underwent surgical andendovascular treatment, and the relationship between these findings and mortality rates.Material and methods: After diagnosis with cranial computed tomography, the localization of aneurysms wasdetermined by computed tomography angiography or dynamic cerebral angiography, 101 patients underwentstandard open microsurgery, and 7 patients underwent embolization by endovascular surgery. Temporary clipswere used for 30 seconds to 4 minutes (average 2 minutes). Complete obliteration of the aneurysm neckwas confirmed by puncture after the permanent clip was placed. Intraoperative controlled hypotension andprophylactic antibiotics were administered.Results: 75 (70.09%) of the cases were female and 32 (29.9%) were male. The female/male ratio was 2.34.The mean age of the cases was 51.9 years. The most common first complaint was headache and vomiting in75 patients (70.09%). While 85 (79.4%) of 107 patients were positive in cranial CT, SAH was negative in 22(20.5%). The most common location was the middle cerebral artery with 49 cases (45.79%). When the Fisherclassifications of 23 patients with clinical vasospasm were evaluated, two patients were Grade 1, 7 patientswere Grade 2, 8 patients were grade 4, and 6 patients were grade 4v. While 18 of the patients who developedvasospasm died, 7 of these patients were operated on within the first 24 hours, 5 within 24-48 hours, and 6after 48 hours. While 64 patients recovered without sequelae after the operation, mild to moderate sequelae(hemiparesis, mitosis) developed in 12 patients and hydrocephalus requiring shunt in 3 patients. According tothe Hunt-Hess classification, a total of 31 patients died, 16 of whom were Stage 4-5.Conclusion: The main factors affecting the outcome in the treatment of intracerebral aneurysm are neurologicalexamination at the time of first presentation, multiple aneurysms, Hunt-Hess Stage 4-5 hemorrhages and thepresence of intracerebral hematoma. We think that early surgery can be used for appropriate treatment becauseof the risk of re-bleeding and the safe fight against vasospasm after surgery.

Özet

Amaç: Anevrizma tanısı konularak yatırılan, cerrahi ve endovasküler tedavi uygulanan intrakraniyal anevrizmalıolguların, demografik, klinik-radyolojik bulgularının ve bu bulgularla ölüm oranlarının ilişkisinin retrospektif olarakincelenmesi amaçlandı.Gereç ve yöntem: Kraniyal bilgisayarlı tomografi ile teşhis konulduktan sonra anevrizmaların lokalizasyonu,bilgisayarlı tomografi anjiyografi veya dinamik serebral anjiyografi ile tesbit edilen 101 hastaya standart açıkmikrocerrahi, 7 hastaya ise endovasküler cerrahi yolla embolizasyon yapıldı. Geçici klip 30 sn ile 4 dk arasındadeğişen sürelerde (ortalama 2 dk) kullanıldı. Kalıcı klip konulduktan sonra ponksiyon yapılarak anevrizmaboynunun tam olarak oblitere edildiği doğrulandı. İntraoperatif kontrollü hipotansiyon ve profilaktik antibiyotikuygulandı.Bulgular: Olguların 75’i (%70,09) kadın, 32’si (%29,9) erkekti. Kadın/erkek oranı 2,34 idi. Olguların yaşortalaması 51,9 saptandı. En sık görülen ilk şikâyet 75 hastada (%70,09) baş ağrısı ve kusma idi. 107 olgunun85 (%79,4)’inde kraniyal BT’de SAK pozitif iken 22 (%20,5)’sinde negatif idi. En sık yerleşim yeri 49 olgu(%45,79) ile orta serebral arter idi. Klinik vazospazm gelişen 23 olgunun Fisher sınıflamaları değerlendirildiğinde;2 hastada Evre 1, 7 hastada Evre 2, 8 hastada Evre 3, 6 hastada Evre 4 tespit edildi. Vazospam gelişenhastaların 18 tanesi eksitus olurken, bu hastaların 7 tanesi ilk 24 saat içinde, 5’i 24-48 saat içinde, 6’sı 48 saatsonrasında opere edildi. 64 hasta operasyon sonrası sekelsiz olarak iyileşirken, 12 hastada hafif-orta düzeydesekel (hemiparazi, mitoz), 3 hastada şant ihtiyacı gerektiren hidrosefali gelişti. Hunt-Hess sınıflamasına göre16’sı Evre 4-5 olan total 31 olgu eksitus oldu.Sonuç: İntraserberal anevrizma tedavisinde sonucu etkileyen faktörlerin başında, ilk geliş anındaki nörolojikmuayene, anevrizmanın çoğul olması, Hunt-Hess Evre 4-5 kanamalar ve intraserebral hematom varlığıgelmektedir. Tekrar kanama riski ve ameliyat sonrası vazospam ile güvenli mücadeleye olanak sağlamasınedeni ile erken cerrahinin uygun tedavi zamanlaması olduğunu düşünmekteyiz.

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Cite This Article

ARSLAN, S., ALBAYRAK, H. K., ÖZATEŞ, M. Ö., KAZANCI, A., GÜRÇAY, A. G., GÜRCAN, O., AYBERK, G. (2022). Investigation of demographic, clinical and radiological findings of cases with intracranial aneurysm: 107 cases, single center experience. Pamukkale Tıp Dergisi, Cilt: 15 - Sayı: 2, 205–212. https://ajindex.com/articles/696385

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