Journals / Kırıkkale Üniversitesi Tıp Fakültesi Dergisi / 2022 / Cilt: 24 - Sayı: 1

THE EFFECTS OF EXENATIDE TREATMENT ON METABOLIC PARAMETERS, GHRELIN, GDF-15 AND FGF-21 IN OBESE TYPE 2 DIABETIC PATIENTS

Obez Tip 2 Diyabetik Hastalarda Eksenatid Tedavisinin Metabolik Parametreler, Ghrelin, GDF-15 ve FGF-21 Üzerine Etkileri

Pages
110–117
Publication Date
2022-04-30
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this study we aimed to investigate the effects of exenatide on ghrelin, FGF-21 and GDF-15 which are known to be associated with appetite and metabolic disorders.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Exenatide and similar drugs which have Glucagon Like Peptide-1(GLP-1) like effects have been used frequently in the treatment of diabetes and obesity in recent years.
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Key Findings & Data:Objective: Exenatide and similar drugs which have Glucagon Like Peptide-1(GLP-1) like effects have been used frequently in the treatment of diabetes and obesity in recent years.
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Conclusion & Impact:In this study we aimed to investigate the effects of exenatide on ghrelin, FGF-21 and GDF-15 which are known to be associated with appetite and metabolic disorders.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:obezite · eksenatid · ghrelin

Abstract

Objective: Exenatide and similar drugs which have Glucagon Like Peptide-1(GLP-1) like effects have been used frequently in the treatment of diabetes and obesity in recent years. In this study we aimed to investigate the effects of exenatide on ghrelin, FGF-21 and GDF-15 which are known to be associated with appetite and metabolic disorders.

Özet

Amaç: Glukagon Benzeri Peptid-1(GLP-1) benzeri etkileri olan eksenatid ve benzeri ilaçlar son yıllarda diyabet ve obezite tedavisinde sıklıkla kullanılmaktadır. Bu çalışmada eksenatidin iştah ve metabolik bozukluklarla ilişkili olduğu bilinen hormonal özellikli peptidler olan ghrelin, FGF-21 ve GDF-15 üzerine etkilerini araştırmayı amaçladık.

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Cite This Article

YILMAZ, M. Ö., ÖZCAN, O. (2022). THE EFFECTS OF EXENATIDE TREATMENT ON METABOLIC PARAMETERS, GHRELIN, GDF-15 AND FGF-21 IN OBESE TYPE 2 DIABETIC PATIENTS. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi, Cilt: 24 - Sayı: 1, 110–117. https://ajindex.com/articles/685667

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