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Journals / Journal of Experimental and Clinical Medicine / 2012 / Cilt: 29 - Sayı: 4

Östrojen hormonu ve menopoz

B.zuhal ALTUNKAYNAK
Deniz ÜNAL
Selina AKSAK
Bünyami ÜNAL
Pages
252–256
Publication Date
2012-12-27
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Med., 2012; 29:252-256

📌 3 Key Takeaways

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Objective & Hypothesis:Ronnekleİnsanoğlunun en önemli sağlık problemleri arasında olan over yaşlanması ve menopozla birlikte dişi hormon sisteminde düzensizlikler baş göstermektedir.
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Key Findings & Data:Östrojen hormonu azalmakta ve buna bağlı olarak osteoporoz, kardiyovasküler rahatsızlıklar, Alzheimer hastalığı, artrit, katarakt, over ve kolon kanserleri, diyabet, diş ve çene bozuklukları gibi patolojilerin görülme sıklığında artış saptanmaktadır.
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Conclusion & Impact:Med., 2012; 29:252-256
🔬Design:Review & Systematic Survey
📍Scope:2012 Verileri
⚙️Variables:Menopoz · over yaşlanması · östrojenenin etkileri (menopause

Abstract

Ronnekleİnsanoğlunun en önemli sağlık problemleri arasında olan over yaşlanması ve menopozla birlikte dişi hormon sisteminde düzensizlikler baş göstermektedir. Östrojen hormonu azalmakta ve buna bağlı olarak osteoporoz, kardiyovasküler rahatsızlıklar, Alzheimer hastalığı, artrit, katarakt, over ve kolon kanserleri, diyabet, diş ve çene bozuklukları gibi patolojilerin görülme sıklığında artış saptanmaktadır. Bu derlemede östrojen hormonununtemel etki mekanizmaları, hücresel düzeydeki yansımaları ve organizma üzerindeki etkileri hakkında detaylı bilgiyeulaşılması amaçlanmıştır. Estrogen hormone and menopause Overian aging and menopause, the most important health problems for human being, cause with these problems a lot of irregulations in female hormone system. The estrogen is decreased and parallel with this situation, some pathologies such as osteoporosis, cardiovascular diseases, Alzheimer’s disease, arthritis, cataract, ovarian and colon cancers, diabetes, teeth and jaw disorders may be seen.This review paper presents detailed information about estrogen’s basic effect mechanisms, its reflection on cellular level and effects on organisms. J. Exp. Clin. Med., 2012; 29:252-256

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Cite This Article

ALTUNKAYNAK, B., ÜNAL, D., AKSAK, S., ÜNAL, B. (2012). Östrojen hormonu ve menopoz. Journal of Experimental and Clinical Medicine, Cilt: 29 - Sayı: 4, 252–256. https://ajindex.com/articles/678762

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References (12)

  1. Ahmed, S.A., Hissong, B.D., Verthelyi, D., Donner, K., Becker, K., Karpuzoglu-Sahin, E., 1999. Gender and risk of autoimmune diseases: Pos- sible role of estrogenic compounds. Environ Health Perspect. 107, 681-686.
  2. Alfinito, P.D., Chen, X., Mastroeni, R., Pawlyk, A.C., Deecher, D.C., 2009. Estradiol increases catecholamine levels in the hypothalamus of ovariectomized rats during the dark-phase. Eur. J. Pharmacol. 616, 334-339.
  3. Arreguin-Arevalo, J.A., Nett, T.M., 2005. A nongenomic action of 17beta-estradiol as the mechanism underlying the acute suppression of secre- tion of luteinizing hormone. Biol. Reprod. 73, 115-122.
  4. Belcredito, S., Vegeto, E., Brusadelli, A., Ghisletti, S., Mussi, P., Ciana, P., Maggi, A., 2001. Estrogen neuroprotection: The involvement of the Bcl-2 binding protein BNIP2. Brain Res. 37, 335-342.
  5. Boulware, M.I., Mermelstein, P.G., 2009. Membrane estrogen receptors activate etabotropic glutamate receptors to influence nervous system physiology. Steroids. 74, 608-613. Borrás, C., Gambini, J., López-Grueso, R., Pallardó, F.V., Viña, J., 2010. Direct antioxidant and protective effect of estradiol on isolated mito- chondria. Biochim. Biophys Acta. 1802, 205-211.
  6. Brann, D.W., Dhandapani, K., Wakade, C., Mahesh, V.B., Khan, M.M., 2007. Neurotrophic and neuroprotective actions of estrogen: Basic mechanisms and clinical implications. Steroids. 72, 381-405.
  7. Brinton, R.D., 2008a. The healthy cell bias of estrogen action: Mitochondrial bioenergetics and neurological implications. Trends Neurosci. 31, 529-537.
  8. Brinton, R.D., 2008b. Estrogen regulation of glucose metabolism and mitochondrial function: Therapeutic implications for prevention of Al- zheimer’s disease. Adv. Drug Deliv. Rev. 60, 1504-1511.
  9. Chang, E.C., Charn, T.H., Park, S.H., Helferich, W.G., Komm, B., Katzenellenbogen, J.A., Katzenellenbogen, B.S., 2008. Estrogen receptors alpha and beta as determinants of gene expression: Influence of ligand, dose, and chromatin binding. Mol. Endocrinol. 22, 1032-1043.
  10. Cheung, E., Schwabish, M.A., Kraus, W.L., 2003. Chromatin exposes intrinsic differences in the transcriptional activities of estrogen receptors alpha and beta. E.M.B.O. J. 22, 600-611.
  11. Chen, J., Adachi, N., Liu, K., Arai, T., 1998. The effects of 17 beta-estradiol on ischemia-induced neuronal damage in the gerbil hippocampus. Neuroscience. 87, 817-822.
  12. Chen, J.Q., Cammarata, P.R., Baines, CP., Yager, J.D., 2009. Regulation of mitochondrial respiratory chain biogenesis by estrogens/estr