Journals / Journal of Experimental and Clinical Medicine / 2021 / Cilt: 38 - Sayı: 2

Effect Of Zinc Deficiency On Cognitive Function in Females With Iron Deficiency Anemia

Pages
111–114
Publication Date
2021-04-03
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

MoCA score (r= 0.803, p=0,000

📌 3 Key Takeaways

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Objective & Hypothesis:Background Iron deficiency and zinc deficiency had been known to disturb congnitive functions especially in infants and preschool children.
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Key Findings & Data:Methods: We designed a randomized controlled prospective study. 41 iron deficient female patients and 40 healthy volunteers were involved in the study Results: The average MoCA score ± SD was 24,63 ± 4,3 (range 11–30) in ıron deficiency anemia (IDA), and 27.43± 2.02 (23-30) in healthy volunteers.
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Conclusion & Impact:MoCA score (r= 0.803, p=0,000
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Anemia · Cognitive Function · Zinc

Abstract

Background Iron deficiency and zinc deficiency had been known to disturb congnitive functions especially in infants and preschool children. Our purpose was to evaluate the effect of zinc deficiency and iron deficiency on cognitive function (with Montreal Cognitive Assesment [MoCA] score) in females. Methods: We designed a randomized controlled prospective study. 41 iron deficient female patients and 40 healthy volunteers were involved in the study Results: The average MoCA score ± SD was 24,63 ± 4,3 (range 11–30) in ıron deficiency anemia (IDA), and 27.43± 2.02 (23-30) in healthy volunteers. Zinc level was 97.06 (40.8–146.8) mg/dl and 257.5 (128.2–463.7) in IDA and healthy volunteers respectively. MoCA score (r= 0.803, p=0,000

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Cite This Article

ASLAN, N. A., KELKİTLİ, E., ÖZTÜRK, N. (2021). Effect Of Zinc Deficiency On Cognitive Function in Females With Iron Deficiency Anemia. Journal of Experimental and Clinical Medicine, Cilt: 38 - Sayı: 2, 111–114. https://ajindex.com/articles/678030

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References (6)

  1. Aruga, J. (2004). The role of Zic genes in neural development. Mol Cell Neurosci, 26(2), 205-221. doi: 10.1016/j.mcn.2004.01.004 Bhatnagar, S., & Taneja, S. (2001). Zinc and cognitive development. Br J Nutr, 85 Suppl 2, S139-145. doi: 10.1079/bjn2000306 Chowanadisai, W., Graham, D. M., Keen, C. L., Rucker, R. B., & Messerli, M. A. (2013). A zinc transporter gene required for development of the nervous system. Commun Integr Biol, 6(6), e26207. doi: 10.4161/cib.26207 Cumming, T. B., Churilov, L., Linden, T., & Bernhardt, J. (2013). Montreal Cognitive Assessment and Mini-Mental State Examination are both valid cognitive tools in stroke. Acta Neurol Scand, 128(2), 122-129. doi: 10.1111/ane.12084
  2. Falkingham, M., Abdelhamid, A., Curtis, P., Fairweather-Tait, S., Dye, L., & Hooper, L. (2010). The effects of oral iron supplementation on cognition in older children and adults: a systematic review and meta-analysis. Nutr J, 9, 4. doi: 10.1186/1475-2891-9-4
  3. Grabrucker, S., Boeckers, T. M., & Grabrucker, A. M. (2016). Gender Dependent Evaluation of Autism like Behavior in Mice Exposed to Prenatal Zinc Deficiency. Front Behav Neurosci, 10, 37. doi: 10.3389/fnbeh.2016.00037 Hershko, C., & Camaschella, C. (2014). How I treat unexplained refractory iron deficiency anemia. Blood, 123(3), 326-333. doi: 10.1182/blood-2013-10-512624
  4. Jiang, Y. G., Fang, H. Y., Pang, W., Liu, J., Lu, H., Ma, Q., & Fang, H. T. (2011). Depressed hippocampal MEK/ERK phosphorylation correlates with impaired cognitive and synaptic function in zinc-deficient rats. Nutr Neurosci, 14(2), 45-50. doi: 10.1179/1476830510Y.0000000002 Lozoff, B., & Georgieff, M. K. (2006). Iron deficiency and brain development. Semin Pediatr Neurol, 13(3), 158-165. doi: 10.1016/j.spen.2006.08.004 Markiewicz-Zukowska, R., Gutowska, A., & Borawska, M. H. (2015). Serum zinc concentrations correlate with mental and physical status of nursing home residents. PLoS One, 10(1), e0117257. doi: 10.1371/journal.pone.0117257 Maylor, E. A., Simpson, E. E., Secker, D. L., Meunier, N., Andriollo-Sanchez, M., Polito, A.,. Coudray, C. (2006). Effects of zinc supplementation on cognitive function in healthy middle-aged and older adults: the ZENITH study. Br J Nutr, 96(4), 752-760.
  5. Nasreddine, Z. S., Phillips, N. A., Bedirian, V., Charbonneau, S., Whitehead, V., Collin, I.,. Chertkow, H. (2005).
  6. The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. J Am Geriatr Soc, 53(4), 695-699. doi: 10.11