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Journals / Journal of Experimental and Clinical Medicine / 2021 / Cilt: 38 - Sayı: 4

Histopathological effect of platelet-rich plasma on cranial dura mater defects

Kemal PAKSOY
Kerameddin AYDIN
Pages
525–528
Publication Date
2021-10-09
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Providing the regeneration of dura mater in defect situations will contribute to the protection of the barrier feature .In line with this idea, it is thought that PRP can be beneficial for us to reach this goal.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: There are many new studies in the selection of materials used in dura material repair.
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Key Findings & Data:Materials and method: Our study started after we got the approval of Ondokuz Mayıs University Animal Experiments Local Ethics Committee.30 Wistar Albino female rats were used.
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Conclusion & Impact:Conclusion: Providing the regeneration of dura mater in defect situations will contribute to the protection of the barrier feature .In line with this idea, it is thought that PRP can be beneficial for us to reach this goal.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:: Cranial Dura Mater · Histopathology · Platelet-Rich Plasma

Abstract

Objective: There are many new studies in the selection of materials used in dura material repair. Platelet has important function in hemostasis and coagulation. Also, activated platelets initiate the wound healing process. They provide regeneration of tissue with the appropriate type of tissue. In this experimental study, we used platelet-rich plasma (PRP) on dura mater defect due to these properties. Materials and method: Our study started after we got the approval of Ondokuz Mayıs University Animal Experiments Local Ethics Committee.30 Wistar Albino female rats were used. The rats were divided into three groups, each one includes ten. Results: No significant difference was observed in the thickness and surface areas of dura mater in group 1 and group 2. Significant increase was observed in the thickness and surface areas of dura mater in the PRP applied group (Group 3) compared to other groups .New bone areas and new vasculature were observed more frequently in the PRP rooms group (Group 3).Statistical analysis of the data was done by using SPSS 21.0 for Mac (IBM Corporation) statistical package program and based on 0.05 significance level.A significant difference was observed between Group 1 and Group 3 (p> 0.05), a significant difference was observed between both Group 1 and Group 3 and between Group 2 and Group 3 (p <0.05). Conclusion: Providing the regeneration of dura mater in defect situations will contribute to the protection of the barrier feature .In line with this idea, it is thought that PRP can be beneficial for us to reach this goal.

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Cite This Article

PAKSOY, K., AYDIN, K. (2021). Histopathological effect of platelet-rich plasma on cranial dura mater defects. Journal of Experimental and Clinical Medicine, Cilt: 38 - Sayı: 4, 525–528. https://ajindex.com/articles/677852

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