Journals / Harran Üniversitesi Veteriner Fakültesi Dergisi / 2018 / Cilt: 7 - Sayı: 1

Effect on Pregnancy Rates of Injected Lecirelin Acetate (GnRH analogue) after Insemination in the Cows

İneklerde Tohumlama Sonrası Uygulanan Lesirelin Asetat (GnRH Analogu)'ın Gebelik Oranları Üzerine Etkisi

Pages
114–118
Publication Date
2018-07-04
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As a result, it was concluded that either intramuscular or epidural administration of Lecirelin Acetate to cows showing spontaneous oestrus can be used after artificial insemination to increase the pregnancy rates.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In the present study the effects of lecirelin acetate injections applied in different ways after artificial insemination on the pregnancy rate of cows were investigated.
📊
Key Findings & Data:As a material, 180 cows showing the spontaneous oestrus between 50-120 days after parturation and having the sexual cycle at regular intervals and showing no clinical disorders during the treatment process were used.
💡
Conclusion & Impact:As a result, it was concluded that either intramuscular or epidural administration of Lecirelin Acetate to cows showing spontaneous oestrus can be used after artificial insemination to increase the pregnancy rates.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:İnek · Lesirelin asetat · Epidural uygulama

Abstract

In the present study the effects of lecirelin acetate injections applied in different ways after artificial insemination on the pregnancy rate of cows were investigated. As a material, 180 cows showing the spontaneous oestrus between 50-120 days after parturation and having the sexual cycle at regular intervals and showing no clinical disorders during the treatment process were used. The cows were randomly divided into 4 groups as A, B, C and D. In the group A (n = 50) 50 µg lecirelin acetate was injected to the sacrococcygeal epidural space of the animals immediately after the artificial insemination . The animals in the group B (n = 40) were injected with 2 ml physiological saline solution by the same route applied to the animals in the group A. The animals in the group C (n = 50) were injected with 50 µg lecirelin acetate intramuscularly immediately after the artificial insemination. The animals in the group D (n = 40) were injected with 2 ml physiological saline solution by the same route applied to the animals in the group C. Statistically significant in difference (P <0.05) were observed between the pregnancy rates of groups A and B (64%) and (45%). It was detected that there was no significant difference (P>0.05) in the pregnancy rates of the groups C and D (60% and 52,5%, respectively). In addition, no significant difference (P>0.05) was observed between the group A (applied epidural GnRH) and C (applied intramuscular GnRH). As a result, it was concluded that either intramuscular or epidural administration of Lecirelin Acetate to cows showing spontaneous oestrus can be used after artificial insemination to increase the pregnancy rates.

Özet

Bu çalışmada, ineklere suni tohumlama sonrası farklı yollardan lesirelin asetat enjeksiyonlarının gebelik oranları üzerindeki etkisi araştırıldı. Materyal olarak postpartum 50-120. günler arasında kendiliğinden östrüse gelen, düzenli aralıklarla seksüel siklus gösteren ve bu süreçte herhangi bir klinik bozukluk göstermeyen farklı ırk ve yaştan 180 inek kullanıldı. Çalışmada kullanılan inekler rastgele 4 gruba ayrıldı. A grubunda bulunan (n= 50) hayvanlara suni tohumlamadan hemen sonra 50 µg lesirelin asetat, B grubu (n=40), hayvanlara 2 ml serum fizyolojik üst epidural boşluğa uygulandı. C grubu (n=50), hayvanlara suni tohumlamadan hemen sonra kas içi 50 µg lesirelin asetat, D grubuna (n=40), 2 ml serum fizyolojik gene kas içi olarak enjekte edildi. Lesirelin asetatın üst epidural boşluğa uygulandığı A ve B grubunda hayvanların gebelik oranları (sırasıyla % 64, % 45) arasında farklılığın istatistiki açıdan anlamlı olduğu (P<0.05) görüldü. Kas içi uygulama yapılan C ve D grubunda gebelik oranları (sırasıyla % 60, % 52,5) yönüyle arasındaki farkın anlamlı olmadığı (P>0.05) belirlendi. Ayrıca, üst epidural ve kas içi GnRH uygulanan gruplar arasında da istatistiki bir farkın (P>0.05) olmadığı tespit edildi. Sonuç olarak, yapılan çalışmada kendiliğinden östrüse gelen ineklere tohumlama ile birlikte epidural yolla uygulanan GnRH enjeksiyonlarının gebelik oranlarını artırmada faydalı olacağı kanaatine varıldı.

🔖

Cite This Article

CAN, C., YILDIZ, H. (2018). Effect on Pregnancy Rates of Injected Lecirelin Acetate (GnRH analogue) after Insemination in the Cows. Harran Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 7 - Sayı: 1, 114–118. https://ajindex.com/articles/671055

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Anjum IA, Usmani RH, Tunio MT, Abro SH, 2009: Improvement of conception rate in crossbred cattle by using GnRH analogue therapy. Pakistan Vet. J, 29, 93-94.
  2. Annalisa R, Debora C, Maddalena M, Giuseppe M, Massimo S, Luigi SR, 2011: Epidural vs intramuscular administration of lecirelin, a GnRH analogue, for the resolution of follicular cysts in dairy cows. Anim Reprod Sci, 126, 19–22.
  3. Bas S, Pinto CG, Day ML, Schuenemann GM, 2012: Effect of intrauterine administration of gonadotropin releasing hormone on serum LH concentrations in lactating dairy cows. Theriogenology, 78, 1390-1397. Chenault JR, 1990: Effect of fertirelin acetate or buserelin on conception rate at first or second insemination in lactating dairy cows. J Dairy Sci, 73, 633–638.
  4. Dolan S, Evans NP, Richter TA, Nolan AM, 2003: Expression of gonadotropin-releasing hormone and gonadotropin-releasing hormone receptor in sheep spinal cord. Neurosci Lett, 346, 120–122. Espey LL, 1978: Ovarian contractility and its relationship to ovulation: a review. Biol Reprod, 19, 540–551.
  5. Gajewski Z, Thun R, Faundez R, Pawlinski B, 2006: The influence of α-adrenergic receptors stimulator and blockers and beta-blocker on the ovary and endocrinological activity in heifers during ovulation. J Physiol Pharmacol, 57(8), 173–188.
  6. Gumen A, Keskin A, Yilmazbas-Mecitoglu G, Karakaya E, Cevik S, Balci F, 2011:
  7. Effects of GnRH, PGF2α and oxytocin treatmentson conception rate at the time of artificial inseminationin lactating dairy cows. Czech J Anim Sci, 56(6), 279–283.
  8. Hayran M, Özdemir O, 1996: Bilgisayar, istatistik ve tıp. 2. Baskı:
  9. Medikomat hekimler yayın birliği, Ankara,
  10. Türkiye. Herbert CA, Trigg TE, 2005: Application of GnRH in the control and management of fertility in female animals. Anim Reprod Sci, 88, 141-153.
  11. Kaçar C, Yıldız S, Pancarcı ŞM, Kaya M, Güngör Ö, Arı UÇ, 2007: Effect of administration of lesireline five days after artificial ınsemination on pregnancy rates and luteal function in cows. Kafkas Üniv Vet Fak Derg, 13(2), 139-142.
  12. Kaim M, Bloch A, Wolfenson D, Braw-Tal R, Rosenberg M, Voet H, Folman Y, 2003: Effects of GnRH administered to cows at the onset of estrus on timing ofovulation, endocrine responses, and conception. J Dairy Sci, 86, 2012–2021.
  13. Lee CN, Critser JK, Ax RL, Folman Y, 1985: Changes of luteinizing hormone and progesterone for dairy cows after gonadotropin-releasing hormone at first postpartum breeding. J Dairy Sci, 68, 1463–1470.
  14. Lee CN, Maurice E, Ax RL, Pennington JA, Hoffman WF,