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Journals / Türk Hijyen ve Deneysel Biyoloji Dergisi / 2016 / Cilt: 73 - Sayı: 4

A case of Aspergillus flavus complex keratitis treated with voriconazole

Vorikonazol ile tedavi edilen bir Aspergillus flavus kompleks keratit olgusu

Özlem Evren KEMER
Gülşen HAZIROLAN
Dilay ÖZEK
Altan AKSOY
Neriman AKSU
Pages
389–394
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In fungal keratitis it is significant to perform accurate and rapid diagnosis and have accurate knowledge about treatment options

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Fungal keratitis can be caused by yeasts Candida spp. and various filamentous fungi such as Fusarium spp.
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Key Findings & Data:Aspergillus spp. and Alternaria spp.
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Conclusion & Impact:In fungal keratitis it is significant to perform accurate and rapid diagnosis and have accurate knowledge about treatment options
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Fungal keratitis can be caused by yeasts Candida spp. and various filamentous fungi such as Fusarium spp. Aspergillus spp. and Alternaria spp. In fungal keratitis it would be on appropriate approach to know risk factors of epidemiology and predisposing risks, and to start on effective antifungal treatment to the patient with proper laboratory diagnosis. Fungal keratitis is difficult to treat and carries a serious risk factor like intraocular involvement. Traditional antifungal drugs usually have good topical transcorneal penetration, but they are limited to intraocular penetration and systemic therapy. In this paper, it is presented a case of A. flavus complex keratitis successfully treated with oral and topical voriconazole. Although fungal keratitis is occured rarely, it still has a serious prognosis. In fungal keratitis it is significant to perform accurate and rapid diagnosis and have accurate knowledge about treatment options

Özet

Fungal keratitlere, Candida spp. cinsi mayalar ile Fusarium spp. Aspergillus spp. ve Alternaria spp. gibi çeşitli filamentöz mantarlar etken olabilir. Fungal keratitlerde epidemiyolojinin ve predispozan risk faktörlerinin bilinmesi ve doğru laboratuvar tanı ile hastaya etkin antifungal tedavinin başlanması uygun yaklaşımdır. Fungal keratitleri tedavi etmek zordur ve intraoküler tutulum gibi ciddi bir risk faktörü taşır. Geleneksel antifungal ilaçlar genellikle iyi topikal transkorneal penetrasyon sağlar, ancak sistemik tedavi ile göz içi penetrasyonda sınırlı kalırlar. Bu yazıda, oral ve topikal vorikonazol ile başarılı şekilde tedavi edilen A. flavus kompleks keratit olgusu sunulmuştur. Fungal keratitler nadir gözlense de halen kötü prognozla seyretmektedirler. Fungal keratitlerde tanının doğru ve hızlı gerçekleştirilmesi ve tedavi seçenekleri hakkında doğru bilgiye sahip olunması önem arz eder

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Cite This Article

KEMER, Ö. E., HAZIROLAN, G., ÖZEK, D., AKSOY, A., AKSU, N. (2022). A case of Aspergillus flavus complex keratitis treated with voriconazole. Türk Hijyen ve Deneysel Biyoloji Dergisi, Cilt: 73 - Sayı: 4, 389–394. https://ajindex.com/articles/654819

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