Journals / Turkish Journal of Biology / 1997 / Cilt: 21 - Sayı: 2

Sanicula europaea L. ekstresinin in vitro virüsidal etkisi

In vitro virucidal effect of Sanicula europaea L. extract

Pages
181–188
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The fractions seperated from the crude extract by Sephadex gel filtration chromatography were also tested and only fractions I was found to be active.

📌 3 Key Takeaways

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Objective & Hypothesis:The antiviral activity of Sanicula europaea L. extract in a phage-bacterium system was investigated.
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Key Findings & Data:We observed that the water-soluble fraction of Sanicula europaea L. extract had virucidai effects on the growth of phage T2, and that the virucidal activity of the extract increased with increasing incubation time and incubation temperature.
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Conclusion & Impact:The fractions seperated from the crude extract by Sephadex gel filtration chromatography were also tested and only fractions I was found to be active.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The antiviral activity of Sanicula europaea L. extract in a phage-bacterium system was investigated. We observed that the water-soluble fraction of Sanicula europaea L. extract had virucidai effects on the growth of phage T2, and that the virucidal activity of the extract increased with increasing incubation time and incubation temperature. In the presence of mono- and divalent ions in the incubation medium the virucidal activity of the extract disappeared completely. The fractions seperated from the crude extract by Sephadex gel filtration chromatography were also tested and only fractions I was found to be active.

Özet

Sanicula europaea L. ekstrelerinin antiviral aktivitesi bir faj -bakteri sisteminde araştırılmıştır. Bitkisel materyalden su ile hazırlanan ekstrenin T2 fajı üzerinde virüsidal etki gösterdiği, inkübasyon süresi uzatıldığında ve inkübasyon ortamı temperatürü yükseltildiğinde ekstrenin virüsidal aktivitesinin arttığı gözlenmiştir. Ayrıca mono ve divalent iyonların varlığında ekstrenin virüsidal aktivitesi bütünüyle inhibe edilmiştir. Sephadex gel filtrasyon kromatografisinden ayrılan fraksiyonlar da test edildiğinde sadece fraksiyon I'in aktif olduğu bulunmuştur.

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Cite This Article

KARAGÖZ, A., ARDA, N., KURU, A., TURAN, K., OKATAN, Y. (2022). Sanicula europaea L. ekstresinin in vitro virüsidal etkisi. Turkish Journal of Biology, Cilt: 21 - Sayı: 2, 181–188. https://ajindex.com/articles/654463

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