Journals / Turkish Journal of Biology / 2016 / Cilt: 40 - Sayı: 1

Analysis of protein expression changes in the blood plasma of cows during the last month before parturition and 2 months after calving

Pages
206–216
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Multidimensional changes in the cow organism observed on the protein level at the end of pregnancy and during the first months of lactation highlight the immense challenges the organism must overcome to maintain homeostasis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The organism undergoes tremendous changes at the end of pregnancy and beginning of lactation.
📊
Key Findings & Data:The aim of the study was to analyze the physiological changes in cows during the last month of a first pregnancy and the first 2 months of lactation, based on the protein expression in peripheral blood plasma.
💡
Conclusion & Impact:Multidimensional changes in the cow organism observed on the protein level at the end of pregnancy and during the first months of lactation highlight the immense challenges the organism must overcome to maintain homeostasis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The organism undergoes tremendous changes at the end of pregnancy and beginning of lactation. The aim of the study was to analyze the physiological changes in cows during the last month of a first pregnancy and the first 2 months of lactation, based on the protein expression in peripheral blood plasma. Changes were observed in the expression of proteins involved in lipid metabolism (apolipoprotein A-I, apolipoprotein E, apolipoprotein J, and apolipoprotein A-IV); immune defense (complement C4 protein and mannose-binding protein C); blood clotting (fibrinogen alpha chain, fibrinogen gamma B-chain, and fibrinogen-like protein 1); as well as reconstruction, regeneration, and defense of cells and tissues (fibrinogen-like protein 1, glutathione peroxidase 3, endopin-1, Kelch-like ECH-associated protein 1, 72 kDa type IV collagenase, and pigment epithelium-derived factor). Multidimensional changes in the cow organism observed on the protein level at the end of pregnancy and during the first months of lactation highlight the immense challenges the organism must overcome to maintain homeostasis.

🔖

Cite This Article

JAROSZ, A., SKRYPCZAK, W. F., OZGO, M., KURPINSKA, A. K. (2022). Analysis of protein expression changes in the blood plasma of cows during the last month before parturition and 2 months after calving. Turkish Journal of Biology, Cilt: 40 - Sayı: 1, 206–216. https://ajindex.com/articles/654422

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (1)

  1. ReferencesAdler G, Duchinski T, Jasinska A, Piotrowska U (2000). Fibrinogen fractions in the third trimester of pregnancy and in puerperium. Thromb Res 97: 405–410.Arthur MJP, Stanley A, Iredale JP, Rafferty JA, Hembry RM, Friedman SL (1992). Secretion of 72kDa type IV collagenase/gelatinase by cultured human lipocytes. Biochem J 287: 701–707.Behene D, Wolters W (1979). Selenium content and glutathione peroxidase activity in the plasma and erythrocytes of non-pregnant and pregnant woman. J Clin Chem Clin Biochem 17: 133–135. Bouwman LH, Roep BO, Roos A (2006). Mannose-binding lectin: clinical implications for infection, transplantation and autoimmunity. Hum Immunol 67: 247–256.Butler JA, Whanger PD, Tripp MJ (1982). Blood selenium and glutathione peroxidase activity in pregnant women: comparative assays in primates and other animals. Am J Clin Nutr 36: 15–23. Cairoli F, Battocchio M, Veronesi MC, Brambilla D, Conserva F, Eberini I, Wait R, Gianazza E (2006). Serum protein pattern during cow pregnancy: acute-phase proteins increase in the peripartum period. Electrophoresis 27: 1617–1625. Chen L, Fan R, Huang X, Xu H, Zhang X (2012). Reduced levels of serum pigment epithelium-derived factor in women with endometriosis. Reprod Sci 19: 64–69.Chen X, Huang Z, Zhou B, Wang H, Jia G, Qiao J (2014). Expression and purification of porcine Akirin2 in Escherichia coli. Turk J Biol 38: 339–345. Dong M, Ding G, Zhou J, Wang H, Zhao Y, Huang H (2008). The effect of thromboplasts on T lymphocytes: possible regulatory effector molecules—a proteomic analysis. Cell Physiol Biochem 21: 463–472. Famulla S, Lamers D, Hartwig S, Passlack W, Horrighs A, Cramer A, Lehr S, Sell H, Eckel J (2011). Pigment epithelium-derived factor (PEDF) is one of the most abundant proteins secreted by human adipocytes and induces insulin resistance and inflammatory signaling in muscle and fat cells. Intern J Obesity 35: 762–772.Gallery ED, Raftos J, Gyory AZ, Wells JV (1981). A prospective study of serum complement (C3 and C4) levels in normal human pregnancy: effect of the development of pregnancy-associated hypertension. Aust N Z J Med 11: 243–245.Geijn van de FE, Roos A, de Man YA, Laman JD, de Groot CJM, Daha MR, Hazes JMW, Dolhain RJEM (2007). Mannose-binding lectin levels during pregnancy: a longitudinal study. Hum Reprod 22: 362–371.Goff JP (2008). Transition cow immune function and interaction with metabolic diseases. In: Tri-State Dairy Nutrition Conference, pp. 45–57. Hara H, Uchida S, Y