Journals / Journal of Urological Surgery / 2020 / Cilt: 7 - Sayı: 1

Can Neutrophil Count, Lymhocyte Count and Neutrophil-tolymphocyte Ratio Predict Fever Following Percutaneous Nephrolithotomy in Patients Without Risk Factors?

Risk Faktörü Olmayan Hastalarda, Perkütan Nefrolitotomi Sonrası Ateşi Öngermede, Nötrofil, Lenfosit Sayısı ve Nötrofil-lenfosit Oranı Etkin Midir?

Pages
21–26
Publication Date
2022-11-06
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Univariate analysis revealed that preoperative thrombocyte count,lymphocyte count, neutrophil count, and NLR were the parameterss significantly related with fever, yet, in multivariate analysis, the only statisticallysignificant parameters related with post-PCNL fever were age, thrombocyte count, and white blood cell count.Conclusion: When risk factors for fever are excluded, lymphocyte count and NLR appear to be easy-to-use and affordable diagnostic markers topredict postoperative fever in patients undergoing PCNL

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: To examine the relationship of neutrophil counts, lymphocyte count and neutrophil-to-lymphocyte ratio (NLR) with postoperative feverin patients undergoing percutaneous nephrolithotomy (PCNL).Materials and Methods: A total of 519 patients aged over 18 years, who underwent PCNL between January 2005 and January 2013 and had apreoperative white blood cell count between 4000-12,000/µL, were included in this study.
📊
Key Findings & Data:The relationship of these parameters with fever was evaluated with univariate andmultivariate analyses.Results: The group with fever included 50 patients and the group without fever, 469 patients.
💡
Conclusion & Impact:Univariate analysis revealed that preoperative thrombocyte count,lymphocyte count, neutrophil count, and NLR were the parameterss significantly related with fever, yet, in multivariate analysis, the only statisticallysignificant parameters related with post-PCNL fever were age, thrombocyte count, and white blood cell count.Conclusion: When risk factors for fever are excluded, lymphocyte count and NLR appear to be easy-to-use and affordable diagnostic markers topredict postoperative fever in patients undergoing PCNL
🔬Design:Research Article
📍Scope:2005 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: To examine the relationship of neutrophil counts, lymphocyte count and neutrophil-to-lymphocyte ratio (NLR) with postoperative feverin patients undergoing percutaneous nephrolithotomy (PCNL).Materials and Methods: A total of 519 patients aged over 18 years, who underwent PCNL between January 2005 and January 2013 and had apreoperative white blood cell count between 4000-12,000/µL, were included in this study. Conditions that could lead to postoperative fever orimpact blood parameters constituted the exclusion criteria. At the postoperative period, the patients were divided into two groups based on thepresence of fever. Age, gender, Body Mass index, stone size, number of percutaneous access, duration of operation, preoperative white blood cellcount, neutrophils, lymphocytes, and NLR were compared. The relationship of these parameters with fever was evaluated with univariate andmultivariate analyses.Results: The group with fever included 50 patients and the group without fever, 469 patients. The difference between the two groups wasstatistically significant in terms of neutrophil and lymphocyte counts, and NLR. Univariate analysis revealed that preoperative thrombocyte count,lymphocyte count, neutrophil count, and NLR were the parameterss significantly related with fever, yet, in multivariate analysis, the only statisticallysignificant parameters related with post-PCNL fever were age, thrombocyte count, and white blood cell count.Conclusion: When risk factors for fever are excluded, lymphocyte count and NLR appear to be easy-to-use and affordable diagnostic markers topredict postoperative fever in patients undergoing PCNL

Özet

Amaç: Perkütan nefrolitotomi (PNL) yapılan hastalarda lenfosit sayısı ve nötrofil lenfosit oranı (NLO) ile post operatif ateş arasındaki ilişkiyi değerlendirmek. Gereç ve Yöntem: Ocak 2005 - Ocak 2013 tarihleri arasında PNL yapılan 519 hasta çalışmaya alındı. Çalışmaya; 18 yaş ve üzeri, preoperatiferatif beyaz küre sayısı 4000-12,000 103 /µL arasında olan hastalar alındı. Postoperatif dönemde ateş yapabilecek ya da kan parametrelerini etkileyecek durumlar çalışma dışı bırakıldı. Postoperatif dönemde hastalar ateşi 38,5 °C üzeri olan ve ateşi olmayan olarak iki gruba ayrıldı. Bulgular: Ateş olan grupta 50 hasta, ateş olmayan grupta 469 hasta vardı. Gruplar arasında yaş, cinsiyet, Beden Kitle indeksi, giriş sayısı, taş boyutu, beyaz küre ve trombosit sayısı bakımından istatistiksel olarak anlamlı farklılık yoktu. Ancak nötrofil sayısı, lenfosit sayısı ve NLO değerleri arasında her iki grup arasındaki fark istatistiksel olarak anlamlı bulundu. Univaryant analizde preopeatif trombosit, lenfosit, nötrofil sayısı ve NLO anlamlıyken multivaryant analizde yaş, trombosit ve beyaz küre sayısı anlamlı çıkmıştır. Sonuç: PNL yapılan hastalarda ateş oluşturabilecek risk faktörleri dışladığında lenfosit sayısı ve NLO postoperatif ateşi öngörmede kullanılabilecek kolay ve ucuz bir tanı aracı olarak gözükmektedir.

🔖

Cite This Article

DEMİRTAŞ, A., SÖNMEZ, G., TOMBUL, Ş. T., DEMİRTAŞ, T., BAYDİLLİ, N. (2022). Can Neutrophil Count, Lymhocyte Count and Neutrophil-tolymphocyte Ratio Predict Fever Following Percutaneous Nephrolithotomy in Patients Without Risk Factors?. Journal of Urological Surgery, Cilt: 7 - Sayı: 1, 21–26. https://ajindex.com/articles/652645

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Draga RO, Kok ET, Sorel MR, Bosch RJ, Lock TM. Percutaneous nephrolithotomy: factors associated with fever after the first postoperative day and systemic inflammatory response syndrome. J Endourol 2009;23:921-927
  2. Cadeddu JA, Chen R, Bishoff J, Micali S, Kumar A, Moore RG, et al. Clinical significance of fever after percutaneous nephrolithotomy. Urology 1998;52:48-50
  3. Sharifi Aghdas F, Akhavizadegan H, Aryanpoor A, Inanloo H, Karbakhsh M. Fever after percutaneous nephrolithotomy: contributing factors. Surg Infect (Larchmt) 2006;7:367-371
  4. Nuutila J, Lilius EM. Distinction between bacterial and viral infections. Curr Opin Infect Dis 2007;20:304-310
  5. Lutfiyya MN, Henley E, Chang LF, Reyburn SW. Diagnosis and treatment of community-acquired pneumonia. Am Fam Physician 2006;73:442-450
  6. Shapiro MF,Greenfield S. The complete blood count and leukocyte differential count. An approach to their rational application. Ann Intern Med 1987;106:65-74
  7. Seebach JD, Morant R, Ruegg R, Seifert B, Fehr J. The diagnostic value of the neutrophil left shift in predicting inflammatory and infectious disease. Am J Clin Pathol 1997;107:582-591
  8. Wyllie DH, Bowler IC, Peto TE. Bacteraemia prediction in emergency medical admissions: role of C-reactive protein. J Clin Pathol 2005;58:352-356
  9. Chalupa P, Beran O, Herwald H, Kasprikova N, Holub M. Evaluation of potential biomarkers for the discrimination of bacterial and viral infections. Infection 2011;39:411-417. 10. de Jager CP, van Wijk PT, Mathoera RB, de Jongh-Leuvenink J, van der Poll T, Wever PC. Lymphocytopenia and neutrophil-lymphocyte count ratio predict bacteremia better than conventional infection markers in an emergency care unit. Crit Care 2010;14:R192
  10. Terradas R, Grau S, Blanch J, Riu M, Saballs P, Castells X, Horcajada JP, Knobel H. Eosinophil count and neutrophil-lymphocyte count ratio as prognostic markers in patients with bacteremia: a retrospective cohort study. PLoS One 2012;7:e42860
  11. Mariappan P, Smith G, Moussa SA, Tolley DA. One week of ciprofloxacin before percutaneous nephrolithotomy significantly reduces upper tract infection and urosepsis: a prospective controlled study. BJU Int 2006;98:1075-1079
  12. Doğan HS, Sahin A, Cetinkaya Y, Akdoğan B, Ozden E, Kendi S. Antibiotic prophylaxis in percutaneous nephrolithotomy: prospective study in 81 patients. J Endourol 2002;16:649-653
  13. Seyrek M, Binbay M, Yuruk E, Akman T, Aslan R, Yazici O, et al. Perioperative prophylaxis for p