Journals / Journal of the Turkish-German Gynecological Association / 2007 / Cilt: 8 - Sayı: 2

Gebelikte vajenin berrak hücreli adenokarsinomu: Olgu sunumu

Clear cell adenocarcinoma of vagina during the pregnancy: A case report

Pages
215–217
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, majority of antenatal bleedings were related to obstetrical causes, lower genital tract malignancies should be excluded by basic gynecologic examination and cervical smear screening.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Vaginal clear cell carcinoma is very rare during the pregnancy.
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Key Findings & Data:A 31-year-old woman was admitted by persistent vaginal bleeding at 28th weeks of gestation.
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Conclusion & Impact:However, majority of antenatal bleedings were related to obstetrical causes, lower genital tract malignancies should be excluded by basic gynecologic examination and cervical smear screening.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Vaginal clear cell carcinoma is very rare during the pregnancy. A 31-year-old woman was admitted by persistent vaginal bleeding at 28th weeks of gestation. On pelvic examination, fragile and hemorrhagic mass was detected a 6 by 7 cm mass on anterior vaginal wall adjacent to bladder trigone. Biopsy of the lesion demonstrated clear cell adenocarcinoma of vagina. She has no history for the prenatal exposure to DES. Treatment was postponed to 31 week’s of gestation to achieve lung maturity of fetus and preoperative work-up. She underwent surgical staging following the delivery by cesarean section at 31 week’s of gestation. Preoperative diagnosis was confirmed postoperatively and two metastatic pelvic lymph nodes were detected. She refused postoperative adjuvant radiotherapy. She died at postoperative 6th month due to distant metastasis. However, majority of antenatal bleedings were related to obstetrical causes, lower genital tract malignancies should be excluded by basic gynecologic examination and cervical smear screening.

Özet

Gebelik sırasında vajinal berrak hücreli kanser çok nadirdir. İntrauterin DES maruziyeti olmayan, 31 yaşında, 28 haftalık gebe olan hasta, inatçı vajinal kanama şikayeti ile başvurdu. Yapılan pelvik muayenede; mesane trigonuna komşu, 6-7 cm çapında, frajil kanamalı kitle saptandı. Biyopsi sonucu berrak hücreli vajinal adenokanser olarak rapor edildi. Fetusun akciğer matürasyonun ve yenidoğan yoğun bakım koşullarının sağlanması için tedavi 31. gebelik haftasına kadar ertelendi. Otuzbirinci gebelik haftasında, olgunun sezaryenle doğumunun gerçekleştirilmesini takiben cerrahi evreleme yapıldı. Preoperatif tanı, operasyon spesmeninde konfirme edildi ve 2 adet pelvik lenf nodunda metastaz saptandı. Adjuvan radyoterapiyi reddeden hasta, postoperatif 6. ayda metastatik hastalık nedeni ile kaybedildi. Antenatal kanamaların büyük bir kısmı obstetrik nedenlere bağlı olarak ortaya çıksa da basit bir pelvik muayene ve servikal smear ile aşağı genital kanal maligniteleri kolaylıkla dışlanabilir.

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Cite This Article

KARABACAK, T., ILAY, Ö., PATA, Ö., DİLEK, S., ÇAYAN, F., DİLEK, T. U. K. (2022). Gebelikte vajenin berrak hücreli adenokarsinomu: Olgu sunumu. Journal of the Turkish-German Gynecological Association, Cilt: 8 - Sayı: 2, 215–217. https://ajindex.com/articles/652626

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