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Journals / Gaziantep Tıp Dergisi / 2012 / Cilt: 18 - Sayı: 1

The relationship between thyroglobulin (Tg) levels and distant metastases before radioiodine (RAI) treatment in differentiated thyroid carcinomas

Diferansiye tiroid karsinomlu hastalarda radyoaktif iyot (RAI) tedavi öncesi tiroglobulin (Tg) düzeylerinin uzak metastazlarla ilişkisi

Ebuzer KALENDER
Hasan Deniz DEMİR
Hüseyin KARAOĞLAN
Yusuf Zeki ÇELEN
Umut ELBOĞA
Mustafa YILMAZ
Pages
11–13
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There was a significant difference between the mean Tg levels of Group 1 and 2 (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The aim of our study is to determine the relationship between distant metastases and thyroglobulin (Tg) levels measured before radioiodine (RAI) treatment in differentiated thyroid carcinomas.
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Key Findings & Data:Fifty patients did not have lymph node or distant metastases (Group 1), and 17 patients had distant metastases (Group 2).
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Conclusion & Impact:There was a significant difference between the mean Tg levels of Group 1 and 2 (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The aim of our study is to determine the relationship between distant metastases and thyroglobulin (Tg) levels measured before radioiodine (RAI) treatment in differentiated thyroid carcinomas. Sixty seven patients with near total or total thyroidectomy were included in the study. Fifty patients did not have lymph node or distant metastases (Group 1), and 17 patients had distant metastases (Group 2). Tg and anti-Tg levels of these patients were measured before RAI treatment when TSH>30 mU/l. Serum Tg levels were found 8,5±10,6 ng/ml and 307±142 ng/ml in Group 1 and Group 2, respectively. There was a significant difference between the mean Tg levels of Group 1 and 2 (p

Özet

Çalışmamızın amacı diferansiye tiroid karsinomlarında radyoaktif iyot (RAI) tedavisi öncesi bakılan tiroglobulin (Tg) değerleri ile uzak metastazlar arasındaki ilişkiyi ortaya koymaktır. Çalışmaya total veya totale yakın tiroidektomi geçirmiş 67 diferansiye tiroid karsinomlu hasta dahil edildi. Hastaların 50’sinde lenf nodu ya da uzak metastazı yoktu (Grup 1), 17’sinde ise uzak metastaz mevcuttu (Grup 2). RAI tedavisi öncesinde TSH>30 mU/l iken tüm hastaların anti-Tg ve Tg düzeylerine bakıldı. Serum Tg değerleri Grup 1’de 8,5±10,6 ng/ml, Grup 2’de 307±142 ng/ml olarak bulundu. Grup 1 ve Grup 2’nin Tg ortalamaları arasındaki farkın anlamlı olduğu görüldü (p

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Cite This Article

KALENDER, E., DEMİR, H. D., KARAOĞLAN, H., ÇELEN, Y. Z., ELBOĞA, U., YILMAZ, M. (2022). The relationship between thyroglobulin (Tg) levels and distant metastases before radioiodine (RAI) treatment in differentiated thyroid carcinomas. Gaziantep Tıp Dergisi, Cilt: 18 - Sayı: 1, 11–13. https://ajindex.com/articles/650699

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