Journals / European Journal of Rheumatology / 2019 / Cilt: 6 - Sayı: 2

Subclinical biventricular systolic dysfunction in patients with systemic sclerosis

Pages
89–93
Publication Date
2022-11-06
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Systolic pulmonary artery pressure (SPAP) wasnegatively correlated with both the LV and RV longitudinal peak systolic strain/strain rates (LV, r=−0.554and r=−0.642, respectively, p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Silent myocardial involvement is associated with poor prognosis in patients with systemicsclerosis (SSc).
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Key Findings & Data:Here we aimed to evaluate the subclinical left ventricular (LV) and right ventricular (RV)systolic dysfunction in patients with SSc without any cardiovascular diseases, by using both strain imaging methods, speckle tracking echocardiography (STE) and real-time 3D echocardiography (RT3DE).Methods: A total of 47 patients with SSc and 20 age- and gender-matched healthy controls (HC)were studied.
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Conclusion & Impact:Systolic pulmonary artery pressure (SPAP) wasnegatively correlated with both the LV and RV longitudinal peak systolic strain/strain rates (LV, r=−0.554and r=−0.642, respectively, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Silent myocardial involvement is associated with poor prognosis in patients with systemicsclerosis (SSc). Here we aimed to evaluate the subclinical left ventricular (LV) and right ventricular (RV)systolic dysfunction in patients with SSc without any cardiovascular diseases, by using both strain imaging methods, speckle tracking echocardiography (STE) and real-time 3D echocardiography (RT3DE).Methods: A total of 47 patients with SSc and 20 age- and gender-matched healthy controls (HC)were studied. Conventional echocardiography, STE-based strain imaging, and real-time 3D echocardiography (Bothell, WA, USA) were performed to assess the biventricular deformation. Clinical andserological findings were sought.Results: Conventional echocardiographic LV measurements were similar between SSc and HC. Both theLV and RV longitudinal peak systolic strain/strain rates were significantly impaired in SSc, demonstrating subclinical LV and RV systolic dysfunction (p≤0.001). Systolic pulmonary artery pressure (SPAP) wasnegatively correlated with both the LV and RV longitudinal peak systolic strain/strain rates (LV, r=−0.554and r=−0.642, respectively, p

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Cite This Article

YILMAZ, N., YAVUZ, Ş., ŞAHİN, Ş. T., CENGİZ, B., YURDAKUL, S., ÇAĞATAY, Y., KAYA, E., AYTEKİN, S. (2022). Subclinical biventricular systolic dysfunction in patients with systemic sclerosis. European Journal of Rheumatology, Cilt: 6 - Sayı: 2, 89–93. https://ajindex.com/articles/650438

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References (11)

  1. Kahan A, Coghlan G, McLaughlin V. Cardiac complications of systemic sclerosis. Rheumatology (Oxford) 2009
  2. 48(Suppl 3): 45-8. [CrossRef] 2. Meune C, Vignaux O, Kahan A, Allanore Y. Heart involvement in systemic sclerosis: evolving concept and diagnostic methodologies. Arch Cardiovasc Dis 2010
  3. [CrossRef] 3. Di Cesare E, Battisti S, Di Sibio A, Cipriani P, Giacomelli R, Liakouli V, et al. Early assessment of sub-clinical cardiac involvement in systemic sclerosis (SSc) using delayed enhancement cardiac magnetic resonance (CE-MRI). Eur J Radiol 2013
  4. [CrossRef] 4. Ioannidis JP, Vlachoyiannopoulos PG, Haidich AB, Medsger TA Jr, Lucas M, Michet CJ, et al. Mortality in systemic sclerosis: an international meta-analysis of individual patient data. Am J Med. 2005
  5. [CrossRef] 5. Allanore Y, Meune C, Vonk MC, Airo P, Hachulla E, Caramaschi P, et al. Prevalence and factors associated with left ventricular dysfunction in the EULAR Scleroderma Trial and Research group (EUSTAR) database of systemic sclerosis patients. Ann Rheum Dis 2010
  6. [CrossRef] 6. Allanore Y, Meune C, Vignaux O, Weber S, Legmann P, Kahan A. Bosentan increases myocardial perfusion and function in systemic sclerosis: a magnetic resonance imaging and Tissue-Doppler echography study. J Rheumatol 2006
  7. Meune C, Allanore Y, Pascal O, Devaux JY, Dessault O, Duboc D, et al. Myocardial contractility is early affected in systemic sclerosis: a tissue Doppler echocardiography study. Eur J Echocardiogr 2005
  8. [CrossRef] 8. van den Hoogen F, Khanna D, Fransen J, Johnson SR, Baron M, Tyndall A, et al. 2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League against Rheumatism collaborative initiative. Arthritis Rheum 2013
  9. [CrossRef] 9. Aggarwal AN, Agarwal W. The new ATS/ERS guidelines for assessing the spirometric severity of restrictive lung disease differ from previous standards. Respirology 2007
  10. [CrossRef] 10. Feigenbaum H, Armstrong WF, Ayan T. Feigenbaum’s Echocardiography, 6th Ed. Lippincotts. Williams&Wilkins
  11. . 11. Mizuguchi Y, Oishi Y, Miyoshi H, Iuchi A, Nagase N, Oki T. The functional role of longitudinal, circumferential, and radial myocardial deformation for regulating the early impairment of left ventricu- lar contraction and relaxation in patients with cardiovascular risk factors: A study with two-dimensional strain imaging. J Am Soc Echocardiog