Journals / Uluslararası Hematoloji-Onkoloji Dergisi / 2018 / Cilt: 28 - Sayı: 4

Relationship Between Target Delineation and Surface Dose in Breast Radiotherapy Using Helical Tomotherapy

Meme Radyoterapisinde Tomoterapi ile Yüzey Dozu ve Konturlama İlişkisi

Pages
201–207
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The effect of breathing motion on surface dose is observed most obviously on cropped PTVs.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:To investigate the effect of different planning target volumes (PTVs) and the breathing motion on the surface dose with Helical Tomotherapy (HT).
📊
Key Findings & Data:Irradiations with different target volumes (PTV-3, PTV0, PTV+5) using a male randophantom placed on a dynamic platform were performed and measured with MOSFET.
💡
Conclusion & Impact:The effect of breathing motion on surface dose is observed most obviously on cropped PTVs.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

To investigate the effect of different planning target volumes (PTVs) and the breathing motion on the surface dose with Helical Tomotherapy (HT). Irradiations with different target volumes (PTV-3, PTV0, PTV+5) using a male randophantom placed on a dynamic platform were performed and measured with MOSFET. The irradiation of the phantom on the dynamic platform revealed that at least 75%,91% and 104% of the predicted surface dose obtained for PTV-3, PTV 0 and PTV+5, respectively. Statistically significant differencewas observed between static and dynamic measurements for PTV-3 (p= 0.02). Surface dose was decreased with increased breathing frequency and amplitude for PTV 0 without statistical significance. HT enables an effective surface dose in chest wall radiotherapyirrespective of the respiratory movement. The delineation is an important aspect of superficial moving targets such as chest wall intreatment with HT. The effect of breathing motion on surface dose is observed most obviously on cropped PTVs.

Özet

Helikal tomoterapi (HT) ile göğüs duvarı ışınlamasında, farklı planlama hedef hacimlerinin (PTV’ler) ve solunum hareketinin yüzey dozu üzerindeki etkisini araştırmak. Dinamik bir platform üzerine yerleştirilen bir erkek randofantom kullanılarak farklı hedef hacimlerde (PTV-3, PTV0, PTV+5) ışınlamalar yapıldı ve bunlar Mosfet ile ölçüldü. Dinamik fantom kurgusu ile yapılan ışınlama sırasıyla PTV-3, PTV0 ve PTV+5 için öngörülen yüzey dozunun en az %75, %91 ve% 104’ünün elde edildiğini ortaya koymuştur. PTV-3 için statik ve dinamik ölçümler arasında istatistiksel olarak anlamlı fark bulundu (p= 0.02). Yüzey dozu, PTV0 için artmış solunum frekansı ve genliği ile istatistiksel olarak anlamsız bir azalma gösterdi. HT göğüs duvarı radyoterapisinde solunum hareketinden bağımsız olarak etkili bir yüzey dozuna olanak tanır. Konturlama, HT ile tedavide göğüs duvarı gibi yüzeysel hareketli hedefler açısından önemlidir. Hareket etkisi en belirgin olarak traşlanmış PTV’de gözlenir.

🔖

Cite This Article

KARABUGA, H., ARSLAN, S. A., INAN, G. A., ARAL, I. P., CELIK, S., OZTURK, H. F. (2022). Relationship Between Target Delineation and Surface Dose in Breast Radiotherapy Using Helical Tomotherapy. Uluslararası Hematoloji-Onkoloji Dergisi, Cilt: 28 - Sayı: 4, 201–207. https://ajindex.com/articles/644779

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Bray F, Ferlay J, Soerjomataram I, et al. Global Cancer Statistics 2018: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin 68: 394-424, 2018
  2. Clarke M, Collins R, Darby S, et al. Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomized trials. Lancet 366: 2087-106, 2005 3. Buchanan CL, Dorn PL, Fey J, et al. Locoregional recurrence after mastectomy: Incidence and Outcomes. Am Coll Surg 203: 469-474, 2006 4. Mayadev J, Einck J, Elson S, et al. Practice patterns in the delivery of radiation therapy after mastectomy among the University of California Athena Breast Health Network. Clin Breast Cancer 15: 43-47, 2015
  3. Blitzblau RC, Horton JK. Treatment planning technique in patients receiving postmastectomy radiation therapy. Pract Radiat Oncol 3: 241-248, 2013
  4. Pignol JP, Vu TT, Mitera G, et al. Prospective evaluation of severe skin toxicity and pain during postmastectomy radiation therapy. Int J Radiat Oncol Biol Phys 91: 157-164, 2015
  5. Ekici K, Gokce T, Karadogan I, et al. Is helical tomotherapybased intensity-modulated radiotherapy feasible and effective in bilateral synchronous breast cancer? A two-center experience. J BUON 21(1),46-52, 2016
  6. Pignol JP, Olivotto I, Rakovitch E, et al. A multicenter randomized trial of breast intensity-modulated radiation therapy to reduce acute radiation dermatitis. J Clin Oncol 26: 2085- 2092, 2008
  7. Dogan N, Cuttino L, Lloyd R, et al. Optimized dose coverage of regional lymph nodes in breast cancer: the role of inten sity-modulated radiotherapy. Int J Radiat Oncol Biol Phys 68:1238-1250, 2007
  8. Barnett GC, Wilkinson JS, Moody AM, et al. Randomized controlled trial of forward-planned intensity-modulated radiotherapy for early breast cancer: interim results at 2 years. Int J Radiat Oncol Biol Phys 82: 715-723, 2011
  9. Buwenge M, Cammelli S, Ammendolia I, et al. Intensity modulated radiation therapy for breast cancer: current perspectives. Breast Cancer (Dove Med Press) 9: 121-126, 2017 12. Cendales R, Schiappacasse L, Schnitman F, et al. Helical tomotherapy in patients with breast cancer and complex treatment volumes. Clin Transl Oncol 13: 268-274, 2011
  10. Cheek D, Gibbons JP, Rosen II, Hogstrom KR. Accuracy of TomoTherapy treatments for superficial target volumes. Med Phys 35: 3565-3573, 2008
  11. Ramsey CR, Seibert RM, Robison B, Mitch