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Journals / Ulusal Travma ve Acil Cerrahi Dergisi / 2020 / Cilt: 26 - Sayı: 1

High C-reactive protein level as a predictor for appendiceal perforation

Yüksek C-reaktif protein seviyesi apendiks perforasyonu için belirteç olabilir

Ömer Vefik ÖZOZAN
Veli VURAL
Pages
63–66
Publication Date
2022-11-06
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

C-reactive protein (AUC: 0.81, p

📌 3 Key Takeaways

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Objective & Hypothesis:BACKGROUND: Between 18% and 34% of acute appendicitis (AA) patients may have complicated appendicitis.
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Key Findings & Data:Perforation increases morbidity and mortality.
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Conclusion & Impact:C-reactive protein (AUC: 0.81, p
🔬Design:Review & Systematic Survey
📍Scope:2014 Verileri
⚙️Variables:Domain Parameters

Abstract

BACKGROUND: Between 18% and 34% of acute appendicitis (AA) patients may have complicated appendicitis. Perforation is themost important complication of AA. Perforation increases morbidity and mortality. In this study, we aimed to investigate the role ofbasic inflammatory markers in the diagnosis of perforated AA.METHODS: A retrospective chart review was conducted of patients who underwent appendectomy with a diagnosis of AA betweenJanuary 2014 and October 2019 at Akdeniz University Faculty of Medicine; and between December 2017 and October 2019 at IstinyeUniversity Faculty of Medicine Hospital. Markers recorded were as follows: white blood cell count, neutrophils, lymphocytes, platelets,c-reactive protein, mean platelet volume, red cell distribution width and eosinophils. Hematological indices were combined to generatethe following three ratios: white cell neutrophil ratio, platelet lymphocyte ratio and neutrophil-lymphocyte ratio.RESULTS: A total of 536 patients with a diagnosis of AA underwent an operation. There were 344 (64.1%) male patients and 192(35.9%) female patients. The mean age of the patients was 36.7±16.2 (15-88) years. There were 94 (17.5%) patients with perforatedAA and 442 (82.5%) patients with non-perforated AA. C-reactive protein (AUC: 0.81, p

Özet

AMAÇ: Akut apandisit (AA) hastalarının %18 ile %34’ü komplike apandisit tanısı almıştır. AA’nın en önemli komplikasyonu perforasyondur. Perforasyon morbidite ve mortaliteyi arttırır. Bu çalışmada temel enflamatuvar belirteçlerin perfore AA tanısındaki rolünü araştırmayı amaçladık. GEREÇ VE YÖNTEM: Akdeniz Üniversitesi Tıp Fakültesi’nde; Ocak 2014–Ekim 2019 ve Aralık 2017–Ekim 2019 tarihleri arasında İstinye Üniversitesi Tıp Fakültesi Hastanesi’nde AA tanısı ile apendektomi yapılan hastaların retrospektif dosya incelemesi yapıldı. Kaydedilen belirteçler aşağıdaki gibiydi: lökosit sayısı, nötrofil, lenfosit, trombosit sayımı, C-reaktif protein, ortalama trombosit hacmi, kırmızı hücre dağılım genişliği ve eozinofiller. Aşağıdaki üç oranın üretilmesi için hematolojik endeksler çalıştırıldı; beyaz küre nötrofil oranı, trombosit lenfosit oranı ve nötrofil lenfosit oranı. BULGULAR: Akut apandisit tanısı olan toplam 536 hasta ameliyat edildi. Bu hastaların 344’ü (%64.1) erkek ve 192’si (%35.9) kadın idi. Hastaların yaş ortalaması 36.7±16.2 (15–88) idi. Perfore AA olan 94 (%17.5) ve perfore olmayan AA olan 442 (%82.5) hasta vardı. C-reaktif protein (AUC: 0.81, p

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Cite This Article

ÖZOZAN, Ö. V., VURAL, V. (2022). High C-reactive protein level as a predictor for appendiceal perforation. Ulusal Travma ve Acil Cerrahi Dergisi, Cilt: 26 - Sayı: 1, 63–66. https://ajindex.com/articles/644435

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