The diagnostic value of irisin in patients with acute abdominal pain: A preliminary study

Themean irisin value of the hospitalized patients (7.98±3.11 mcg/mL) was significantly higher than that of the discharged patient group(6.38±3.09 mcg/mL) and the controls (control vs. discharged: p=0.202; control vs. hospitalized: p

📌 3 Key Takeaways

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Objective & Hypothesis:BACKGROUND: The aim of this study was to investigate the prognostic value of irisin by examining the serum level of this smoothmuscle protein in patients presenting at the emergency department (ED) with acute abdominal pain.METHODS: This research was performed as a single-center, prospective, cross-sectional study.

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Key Findings & Data:In all, 213 adult patients presentingat the ED with acute abdominal pain and 140 healthy controls were enrolled.

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Conclusion & Impact:Themean irisin value of the hospitalized patients (7.98±3.11 mcg/mL) was significantly higher than that of the discharged patient group(6.38±3.09 mcg/mL) and the controls (control vs. discharged: p=0.202; control vs. hospitalized: p

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

BACKGROUND: The aim of this study was to investigate the prognostic value of irisin by examining the serum level of this smoothmuscle protein in patients presenting at the emergency department (ED) with acute abdominal pain.METHODS: This research was performed as a single-center, prospective, cross-sectional study. In all, 213 adult patients presentingat the ED with acute abdominal pain and 140 healthy controls were enrolled. The serum irisin level was correlated with the leukocyte,C-reactive protein, amylase, and creatine kinase values. The irisin level was compared between groups of those who were admitted ordischarged, and those who received surgical or medical treatment.RESULTS: The mean irisin level of the 213 patients and the 140 controls was 6.81±3.17 mcg/mL vs. 5.69±2.08 mcg/mL. Themean irisin value of the hospitalized patients (7.98±3.11 mcg/mL) was significantly higher than that of the discharged patient group(6.38±3.09 mcg/mL) and the controls (control vs. discharged: p=0.202; control vs. hospitalized: p

Özet

AMAÇ: Akut karın ağrısı şikayeti ile acil servise müracaat eden hastalarda düz kas proteini Irisin’in serum düzeyini ölçerek tanısal değerini araştırmak amacıyla bu çalışma yapıldı. GEREÇ VE YÖNTEM: Bu araştırma, tek merkezli, ileriye yönelik ve kesitsel bir çalışma olarak yapıldı. Akut karın ağrısı şikayeti ile acil servise başvuran 213 erişkin hasta ve 140 kişilik sağlıklı kontrol grubu dahil edildi. Serum irisin düzeyleri, lökosit, C-reaktif protein, amilaz ve kreatin kinaz değerleri ile karşılaştırıldı. Serum İrisin düzeyleri, yatışı yapılan ile taburcu olan ve cerrahi ile tıbbi tedavi yapılan gruplar da karşılaştırıldı. BULGULAR: Çalışmaya dahil edilen 213 hasta ve 140 kontrol grubu ortalama Irisin düzeyleri 6.81±3.17 mcg/mL ve 5.69±2.08 mcg/mL idi. Hastaneye yatırılan hastaların ortalama Irisin değerleri (7.98±3.11 mcg/mL), taburcu edilen hastaların (6.38±3.09 mcg/mL) ve kontrol grubu olguların Irisin değerlerinden (kontrol grubu – taburcu hasta grubu p=0.202) anlamlı derecede yüksekti (kontrol grubu - hastaneye yatırılan grup p

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Cite This Article

Gümüş, A., Yeniocak, S., Karcıoğlu, Ö., Kalkan, A., Saraç, F., Karadana, G. A., Keklikkıran, Z. Z., Koldaş, M., Korkut, S. (2022). The diagnostic value of irisin in patients with acute abdominal pain: A preliminary study. Ulusal Travma ve Acil Cerrahi Dergisi, Cilt: 24 - Sayı: 6, 539–544. https://ajindex.com/articles/644361

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