Journals / Ulusal Travma ve Acil Cerrahi Dergisi / 2019 / Cilt: 25 - Sayı: 1

Relationship between the albumin level and the anesthesia method and the effect on clinical course in patients with major burns

Majör yanıklı hastaların albümin düzeyinin anestezi yönetimi ile ilişkisi ve klinik gidişte etkinliği

Pages
55–59
Publication Date
2022-11-05
DOI
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⚡ TL;DR(Too Long; Didn't Read)

The cut-off point for the preoperative albumin level affecting postoperative morbidity was determined as ≥2.3 gr/dL (Area Under Curve=0.587; p

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Objective & Hypothesis:BACKGROUND: Due to a massive increase in capillary permeability during the state of shock caused by burns, albumin and intravascular fluid rapidly move to the extravascular areas.
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Key Findings & Data:The aim of this study was to investigate the effect of the preoperative albuminlevel on perioperative morbidity and mortality in patients with major burns.METHODS: Demographic data, preoperative albumin levels, surgical records, and clinical follow-up records of a total of 61 patients who underwent surgery for major burns in our hospital for the last 2 years were examined.
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Conclusion & Impact:The cut-off point for the preoperative albumin level affecting postoperative morbidity was determined as ≥2.3 gr/dL (Area Under Curve=0.587; p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

BACKGROUND: Due to a massive increase in capillary permeability during the state of shock caused by burns, albumin and intravascular fluid rapidly move to the extravascular areas. Therefore, hypoalbuminemia is seen as an early and prolonged finding in majorburns. Hypoalbuminemia leads to various problems. The aim of this study was to investigate the effect of the preoperative albuminlevel on perioperative morbidity and mortality in patients with major burns.METHODS: Demographic data, preoperative albumin levels, surgical records, and clinical follow-up records of a total of 61 patients who underwent surgery for major burns in our hospital for the last 2 years were examined. Intraoperative complications wererecorded, such as hypotension, bradycardia, low saturation, metabolic acidosis, reduced urine output, and hyperglycemia. Postoperative complications were recorded as intubation and the use of mechanical ventilator, sepsis, ARDS, acute renal failure, tracheotomy,hemorrhage, arrest, pneumonia, urinary tract infection, tissue infection, congestive heart failure, and pleural effusion.RESULTS: In patients with albumin levels measured as 2 gr/dL, intraoperative complications were determined at the ratesof 31.4% and 20.8%, respectively, postoperative complications at 60.0% and 51.5%, respectively, and mortality rates at 40% and 25.8%,respectively (p=0.148, p=0.251, p=0.85, respectively). The cut-off point for the preoperative albumin level affecting postoperative morbidity was determined as ≥2.3 gr/dL (Area Under Curve=0.587; p

Özet

AMAÇ: Yanık şokunda, kapiller permabilitedeki masif artış sebebiyle albümin ve intravasküler sıvı hızlıca ekstravasküler alana yer değiştirir. Bu nedenle hipoalbüminemi majör yanıklarda erken ve uzamış bir bulgu olarak karşımıza çıkar. Hipoalbüminemi çeşitli sorunlara yol açmaktadır. Bu çalışmada, majör yanıklı hastaların ameliyat öncesi dönem albümin düzeylerinin ameliyattaki morbidite ve mortaliteye etkisi araştırıldı. GEREÇ VE YÖNTEM: Hastanemizde 2011–2013 yılları arasında majör yanık nedeniyle ameliyat olmuş 61 hastanın demografik verileri, ameliyat öncesi albümin düzeyleri, ameliyat kayıtları ve servis takipleri incelendi. Ameliyat sırasında komplikasyonlar; hipotansiyon, bradikardi, satürasyon düşüklüğü, metabolik asidoz, idrar çıkımında azalma, hiperglisemi olarak kaydedildi. Ameliyat sonrası komplikasyonlar; entübasyon ve mekanik ventilatöre bağlanma, sepsis, ARDS, akut böbrek yetersizliği, trakeotomi, kanama, arrest, pnömoni, idrar yolu enfeksiyonu, doku enfeksiyon, konjektif kalp yetersizliği, plevral efüzyon olarak kaydedildi. BULGULAR: Albümin düzeyi 2 gr/dL değerinin altında ve üstünde olan hastalar arasında ameliyat esnasında komplikasyonlar sırasıyla 31.4 ve 20.8; ameliyat sonrası komplikasyonlar %60.0 ve %51.5; mortalite oranları %40 ve %25.8 olarak bulunmuştur (p=0.148; p=0.251; p=0.85). Ameliyat sonrası morbiditeyi etkileyen ameliyat öncesi albümin düzeyi için, albümin (g/dL) değerinde ≥2.3’ün kesim noktası olduğu bulunmuştur (AUC=0.587, p

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Cite This Article

Çakırca, M., Sözen, İ., Baydar, M., Yastı, A. Ç., Bindal, G. T. (2022). Relationship between the albumin level and the anesthesia method and the effect on clinical course in patients with major burns. Ulusal Travma ve Acil Cerrahi Dergisi, Cilt: 25 - Sayı: 1, 55–59. https://ajindex.com/articles/644288

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