Journals / Ulusal Travma ve Acil Cerrahi Dergisi / 2020 / Cilt: 26 - Sayı: 4

An investigation into the effects of hemodynamic changes on the patient’s clinical condition during the treatment of patients undergoing aneurysmal subarachnoid hemorrhage

Anevrizmal subaraknoid kanama geçiren hastalarda tedavi süresince gelişen hemodinamik değişikliklerin kliniğe etkilerinin araştırılması

Pages
563–567
Publication Date
2022-11-06
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

While low GEDI value was found as a risk factor, we couldnot determine an ideal GEDI value.

📌 3 Key Takeaways

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Objective & Hypothesis:BACKGROUND: In this study, we investigated the hemodynamic changes in patients with aneurysmal subarachnoid hemorrhage(aSAH) during the intensive care unit and the effects of PiCCO on the hemodynamic clinical course during hydration and hypertensiontreatment.METHODS: In our study, 15 adult aSAH patients, whose aneurysm had been treated by surgery or coiling, were examined for thesigns of vasospasm in between the dates 03/01/2015 and 01/03/2016.
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Key Findings & Data:The PICCO measurement was made at least twice in a day.Positive daily fluid balance was attempted to be at least 1000 mL and the value of the Global end-diastolic index (GEDI) was targetedto 680 to 800 mL/m2 for each patient.
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Conclusion & Impact:While low GEDI value was found as a risk factor, we couldnot determine an ideal GEDI value.
🔬Design:Research Article
📍Scope:2015 Verileri
⚙️Variables:Domain Parameters

Abstract

BACKGROUND: In this study, we investigated the hemodynamic changes in patients with aneurysmal subarachnoid hemorrhage(aSAH) during the intensive care unit and the effects of PiCCO on the hemodynamic clinical course during hydration and hypertensiontreatment.METHODS: In our study, 15 adult aSAH patients, whose aneurysm had been treated by surgery or coiling, were examined for thesigns of vasospasm in between the dates 03/01/2015 and 01/03/2016. The PICCO measurement was made at least twice in a day.Positive daily fluid balance was attempted to be at least 1000 mL and the value of the Global end-diastolic index (GEDI) was targetedto 680 to 800 mL/m2 for each patient. The values of mean arterial pressure (MAP), systolic arterial pressure (SAP), heart rate (HR),central venous pressure (CVP), and cardiac index (CI), GEDI, systemic vascular resistance index (SVRI), extravascular lung water index(ELWI) measured by PiCCO, and daily neurological outcome of patients and GCS values were recorded.RESULTS: It had been observed that CVP value was randomly changing during the volume therapy, but the GEDI value determinedby thermodilution was consistent. A positive correlation was detected between the period of reaching the hospital and the first measuredvalue of SVRI. Low GEDI value was detected as a risk factor in the perspective of vasospasm, but an ideal GEDI value could notbe determined.CONCLUSION: GEDI values were correlated with daily fluid balance. While low GEDI value was found as a risk factor, we couldnot determine an ideal GEDI value.

Özet

AMAÇ: Çalışmamızda anevrizmal subaraknoid kanama (aSAK) hastalarının yoğun bakım izlemlerinde hemodinamik değişiklikleri ve hidrasyon, hipertansiyon tedavisi sırasında PiCCO ile ölçülen hemodinamik parametrelerin klinik seyre etkisini inceledik. GEREÇ VE YÖNTEM: Çalışmamızda 01.03.2015 ve 01.03.2016 tarihleri arasında cerrahi klip veya endovasküler koil ile anevrizması tedavi edilen, erişkin, 15 aSAK hastası vazospazm açısından incelendi. Günde en az iki kez PiCCO ölçümü yapıldı. Sıvı tedavisi günlük en az 1000 mL pozitiflik olacak şekilde, Global end-diyastolik İndeks (GEDİ) değeri 680–800 mL/m2 şeklinde hedeflendi. Hastaların geliş ortalama arter basıncı (OAB), sistolik arter basıncı (SAB), kalp atım hızı (KAH), santral venöz basınç (CVP) ve kardiyak indeks (CI), GEDI, sistemik vasküler rezistans indeksi (SVRI), ekstravasküler akciğer volüm indeksi (ELWI) değerleri kaydedildi. Hastaların günlük nörolojik muayeneleri, klinik vazospazm bulguları, GKS değerleri kaydedildi. BULGULAR: Hastaların volüm durumları ve volüm tedavisi takibinde CVP değerinin rastgele değiştiği fakat termodilüsyon ile saptanan GEDI değerinin uyumlu olduğu görüldü. Hastaneye geliş süresi ile ilk ölçülen SVRI değeri arasında ileri düzeyde pozitif korelasyon saptandı. Düşük GEDI değerinin vazospazm açısından risk faktörü olduğu bulundu. TARTIŞMA: Volüm tedavisinin takibindeki değişikliklerle GEDI değerindeki değişikliklerin uyumlu olduğu görüldü. Düşük GEDI değerinin vazospazm açısından risk faktörü olduğu bulunmasına rağmen, önerilecek ideal bir GEDI değeri saptanamadı.

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Cite This Article

MAMMADOV, O., MAMMADOV, N. Y., JİMA, A. K., ORHUN, G., AKINCI, İ. Ö., ALİ, A. (2022). An investigation into the effects of hemodynamic changes on the patient’s clinical condition during the treatment of patients undergoing aneurysmal subarachnoid hemorrhage. Ulusal Travma ve Acil Cerrahi Dergisi, Cilt: 26 - Sayı: 4, 563–567. https://ajindex.com/articles/644189

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