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Journals / Türk Yoğun Bakım Dergisi / 2022 / Cilt: 20 - Sayı: Ek 1

Relationship Between Intubation and Mortality in COVID-19 Patients with Moderate ARDS, Secondary Bacterial Infection Status

Moderate ARDS’li COVİD-19 Hastalarında Entübasyon ve Mortalite İlişkisi, Sekonder Bakteriyel Enfeksiyon Durumu

Derya TATLISULUOĞLU
Gülçin Hilal ALAY
Kadir BULUT
Burcu İLERİ FİKRİ
Alev ÖZTAŞ
Güldem TURAN
Pages
108–116
Publication Date
2022-11-06
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: In the group of patients who were intubated after the first 24 h, the number of mechanical ventilator days was 9.15±8.58 (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In many studies on patients with acute respiratory distress syndrome (ARDS) caused by severe acute respiratory syndrome coronavirus-2, the mortality rate was found to be high in intubated patients.
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Key Findings & Data:The aim of this study was to try to understand how intubation affects mortality in patients with coronavirus disease (COVID) polymerase chain reaction-positive ARDS and to understand the relationship between intubation and mortality in the patient group whose PaO2/FiO2 is 100-150 mmHg (moderate) and who have difficulty in intubation decision.
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Conclusion & Impact:Results: In the group of patients who were intubated after the first 24 h, the number of mechanical ventilator days was 9.15±8.58 (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: In many studies on patients with acute respiratory distress syndrome (ARDS) caused by severe acute respiratory syndrome coronavirus-2, the mortality rate was found to be high in intubated patients. The aim of this study was to try to understand how intubation affects mortality in patients with coronavirus disease (COVID) polymerase chain reaction-positive ARDS and to understand the relationship between intubation and mortality in the patient group whose PaO2/FiO2 is 100-150 mmHg (moderate) and who have difficulty in intubation decision. Materials and Methods: Patient information was obtained by retrospectively examining the hospital computer database and patient files. Three hundred thirteen patients were included in the study. The patients were divided into two groups as intubated and non-intubated according to their intubation status after the first 24 h of their admission to the intensive care unit (ICU) and their intubation status when PaO2/FiO2 was 100-150 mmHg (moderate ARDS). Results: In the group of patients who were intubated after the first 24 h, the number of mechanical ventilator days was 9.15±8.58 (p

Özet

Amaç: Şiddetli akut solunum sendromu koronavirüs hastalığı (COVID) virüsünün neden olduğu akut solunum sıkıntısı sendromu (ARDS) hastaları üzerinde yapılan çok sayıda çalışmada, entübe hastalarda ölüm oranı yüksek bulunmuştur. Bu çalışmanın amacı, COVID polimeraz zincirleme reaksiyonu pozitif ARDS olan hastalarda entübasyonun mortaliteyi nasıl etkilediği ve PaO2/Fi02’nin 100-150 mmHg olduğu (moderate), entübasyon kararında zorlanılan hasta grubunda entübasyon ile mortalite arasındaki ilişkiyi anlamaya çalışmaktır. Gereç ve Yöntem: Hasta bilgileri hastane bilgisayar veri tabanından ve hasta dosyalarından retrospektif olarak incelenerek elde edildi. Üç yüz on üç hasta çalışmaya dahil edildi. Hastalar yoğun bakıma yatışlarının ilk 24 saatinden sonraki entübasyon durumuna göre ve PaO2/Fi02’nin 100-150 mmHg (moderate ARDS) olduğunda entübasyon durumuna göre entübe ve non-entübe olacak şekilde iki gruba ayrıldı. Bulgular: İlk 24 saatten sonra entübe edilen hasta grubunda mekanik ventilatör gün sayısı 9,15±8,58 (p

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Cite This Article

TATLISULUOĞLU, D., ALAY, G. H., BULUT, K., FİKRİ, B. İ., ÖZTAŞ, A., TURAN, G. (2022). Relationship Between Intubation and Mortality in COVID-19 Patients with Moderate ARDS, Secondary Bacterial Infection Status. Türk Yoğun Bakım Dergisi, Cilt: 20 - Sayı: Ek 1, 108–116. https://ajindex.com/articles/643368

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References (13)

  1. Chang D, Xu H, Rebaza A, Sharma L, Dela Cruz CS. Protecting health-care workers from subclinical coronavirus infection. Lancet Respir Med 2020;8:e13
  2. Tran K, Cimon K, Severn M, Pessoa- Silva CL, Conly J. Aerosol generating procedures and risk of transmission of acute respiratory infections to healthcare workers: a systematic review. PLoS One 2012;7:e35797
  3. Cheung JC, Ho LT, Cheng JV, Cham EYK, Lam KN. Staff safety during emergency airway management for COVID-19 in Hong Kong. Lancet Respir Med 2020;8:e19
  4. Laghi F, Tobin MJ. Indications for mechanical ventilation. In: Tobin MJ, editor. Principles and practice of mechanical ventilation, 3rd ed. New York: McGraw-Hill, Inc; 2013. pp. 129-62
  5. Wang Y, Lu X, Li Y, Chen H, Chen T, Su N, et al. Clinical Course and Outcomes of 344 Intensive Care Patients with COVID-19. Am J Respir Crit Care Med 2020;201:1430-4
  6. Grasselli G, Zangrillo A, Zanella A, Antonelli M, Cabrini L, Castelli A, et al. Baseline Characteristics and Outcomes of 1591 Patients Infected With SARSCoV- 2 Admitted to ICUs of the Lombardy Region, Italy. JAMA 2020;323:1574-81
  7. ICNARC: ICNARC report on COVID-19 in critical care 17 April 2020. www.icnarc. org (last accessed on 29 June 2020)
  8. Richardson S, Hirsch JS, Narasimhan M, Crawford JM, McGinn T, Davidson KW, et al. Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID- 19 in the New York City Area. JAMA 2020;323:2052-9
  9. Kluge S, Janssens U, Welte T, Weber- Carstens S, Schälte G, Salzberger B, et al. Empfehlungen zur intensivmedizinischen Therapie von Patienten mit COVID- 19 – 3. Version: S1-Leitlinie [German recommendations for treatment of critically ill patients with COVID- 19-version 3]. Pneumologe (Berl) 2020;17:406-25
  10. Tobin MJ. Basing Respiratory Management of COVID-19 on Physiological Principles. Am J Respir Crit Care Med 2020;201:1319-20
  11. Tobin MJ, Gardner WN: Monitoring of the control of ventilation. In: Tobin MJ (ed). Principles and practice of intensive care monitoring. McGraw-Hill, Inc. New York: 1998. p. 415-64
  12. Pfeifer M, Ewig S, Voshaar T, Randerath W, Bauer T, Geiseler J, et al. Positionspapier zur praktischen Umsetzung der apparativen Differenzialtherapie der akuten respiratorischen Insuffizienz bei COVID-19 [Position Paper for the State of the Art Application of Respiratory Support in Patients with COVID- 19 - German Respiratory Society]. Pneumologie 2020;74:337-57
  13. Westhoff M, Schönhofer B, Neum