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Journals / Türk Spor ve Egzersiz Dergisi / 2019 / Cilt: 21 - Sayı: 2

Effects of Melatonin on Some Antioxidant Enzymes in Streptozotocin-induced Diabetic Rats

Deniz Uluışık
Ercan Keskin
Durmuş Hatipoğlu
Pages
217–222
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

The insulin level in diabetes group was lower than control group, while blood glucose level washigher (p

📌 3 Key Takeaways

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Objective & Hypothesis:In this study, it was aimed to determine the effects of melatonin application in experimentally induced diabetes.
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Key Findings & Data:Melatoningroup animals received 50 mg/kg melatonin intraperitoneally in daily for eight weeks.
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Conclusion & Impact:The insulin level in diabetes group was lower than control group, while blood glucose level washigher (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In this study, it was aimed to determine the effects of melatonin application in experimentally induced diabetes. For thispurpose, thirty two adult male Wistar Albino rats were used. Animals in control group were not any treatment. Melatoningroup animals received 50 mg/kg melatonin intraperitoneally in daily for eight weeks. Diabetes was induced by subcutaneousinjections of streptozotocin at dose of 40 mg/kg for two days as a single dose per day in diabetes group animals. Animals inDiabetes+Melatonin group were made diabetic by streptozotocin in the same way and then these animals received 50 mg/kgmelatonin intraperitoneally in daily for eight weeks. In blood samples taken from all animals, insulin, glucose, HbA1c, MDA,GSH, SOD were determined. The insulin level in diabetes group was lower than control group, while blood glucose level washigher (p

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Cite This Article

Uluışık, D., Keskin, E., Hatipoğlu, D. (2022). Effects of Melatonin on Some Antioxidant Enzymes in Streptozotocin-induced Diabetic Rats. Türk Spor ve Egzersiz Dergisi, Cilt: 21 - Sayı: 2, 217–222. https://ajindex.com/articles/642264

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