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Journals / Türk Pediatri Arşivi / 2009 / Cilt: 44 - Sayı: 4

Anticardiolipin antibodies in children with portal vein thrombosis

Portal ven trombozlu çocuklarda antikardiyolipin antikorları

Tufan KUTLU
Fügen Çullu ÇOKUĞRAŞ
E. Mahir GÜLCAN
Tülay ERKAN
Pages
124–126
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusions: IgG anticardiolipin antibodies are significantly associated with portal vein thrombosis in children

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: The aim of this study was to evaluate the frequency of anticardiolipin antibodies in children with portal vein thrombosis and whether anticardiolipin antibodies have effect on thrombosis in the portal vein.
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Key Findings & Data:Material and Method: IgG and IgM anticardiolipin levels were measured in 20 patients with portal vein thrombosis and in 20 healthy controls using an ELISA method.Results: IgG anticardiolipin levels (GPL unit) were found as 13.9±4.8 in the portal vein thrombosis patients and 4.4±1.9 in the control group (p0.05).
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Conclusion & Impact:Conclusions: IgG anticardiolipin antibodies are significantly associated with portal vein thrombosis in children
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: The aim of this study was to evaluate the frequency of anticardiolipin antibodies in children with portal vein thrombosis and whether anticardiolipin antibodies have effect on thrombosis in the portal vein. Material and Method: IgG and IgM anticardiolipin levels were measured in 20 patients with portal vein thrombosis and in 20 healthy controls using an ELISA method.Results: IgG anticardiolipin levels (GPL unit) were found as 13.9±4.8 in the portal vein thrombosis patients and 4.4±1.9 in the control group (p0.05). In seven (35%) portal vein thrombosis patients and in one (5%) in the control group anticardiolipin IgG (p0.05) levels were high (>10 GPL and MPL unit). Conclusions: IgG anticardiolipin antibodies are significantly associated with portal vein thrombosis in children

Özet

Amaç: Portal ven trombozlu çocuklarda antikardiyolipin antikorlarının sıklığının ve portal vendeki tromboz üzerine etkisinin olup olmadığının araştırılması.Gereç ve Yöntem: Bu ileriye dönük çalışmaya portal ven trombozlu 20 ve kontrol grubu olarak sağlıklı 20 çocuk alındı. Antikardiyolipin IgM ve IgG ölçümleri ELISA yöntemi kullanılarak yapıldı. Bulgular: Portal ven trombozlu hastalarda antikardiyolipin IgG düzeyleri 13,9±4,8 GPL ünitesi, kontrol grubunda 4,4±1,9 GPL ünitesi (p0,05) bulundu. Portal ven trombozlu hastaların yedisinde (%35), kontrol grubununun birinde (%5) antikardiyolipin IgG (p0,05) yüksekti (>10 GPL ve MPL ünitesi).Çıkarımlar: Çocuklarda antikardiyolipin IgG, portal ven trombozu ile anlamlı ilişkilidir.

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Cite This Article

KUTLU, T., ÇOKUĞRAŞ, F. Ç., GÜLCAN, E. M., ERKAN, T. (2022). Anticardiolipin antibodies in children with portal vein thrombosis. Türk Pediatri Arşivi, Cilt: 44 - Sayı: 4, 124–126. https://ajindex.com/articles/641559

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