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Journals / Türk Pediatri Arşivi / 2011 / Cilt: 46 - Sayı: 1

Endotel function and thrombotic system evaluation of children whose parents had early onset coronary heart disease

Ebeveynleri erken koroner kalp hastalığı geçirmiş çocuklarda endotel işlevi ve trombotik sistem değerlendirmesi

Aygün DİNDAR
Kemal NİŞLİ
Ümrah AYDOĞAN
Eker Rukiye ÖMEROĞLU
Taner YAVUZ
Helen BORNAUN
C. Naci ÖNER
Türkan ERTUĞRUL
Ümit TÜRKOĞLU
Pages
20–25
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The aim of this study was to investigate some haemostatic and inflammatory markers, in children whose parents had early onset (

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: First-degree relatives of patients who have had an acute myocardial infarction prior to age of 55 years have 2-7 times the risk that their peers have.
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Key Findings & Data:Aim: First-degree relatives of patients who have had an acute myocardial infarction prior to age of 55 years have 2-7 times the risk that their peers have.
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Conclusion & Impact:The aim of this study was to investigate some haemostatic and inflammatory markers, in children whose parents had early onset (
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: First-degree relatives of patients who have had an acute myocardial infarction prior to age of 55 years have 2-7 times the risk that their peers have. The aim of this study was to investigate some haemostatic and inflammatory markers, in children whose parents had early onset (

Özet

Amaç: Bu çal›flman›n amac›; anne ve/veya babas› 55 yafl›n alt›nda koroner arter hastal›¤› (KAH) geçirmifl olan çocuklarda baz› hemostatik ve enflamatuar belirteçlerin düzeylerini araflt›rmak ve bu belirteçlerin KAH’›n geliflme riskini göstermede etkili olup olmad›¤›n› belirlemektir. Gereç ve Yöntem: Bu ileriye dönük çal›flma Fakülte Yerel Etik Kurul izniyle ‹stanbul T›p Fakültesi, Çocuk Kardiyolojisi Bilim Dal›’nda yap›lm›flt›r. Ailesinde 55 yafl alt›nda KAH olan 43 sa¤l›kl› çocuk ayn› yafl ve cinsiyetteki sa¤l›kl› kontrollerle efllefltirilerek doku faktörü (DF), serbest ve toplam doku faktörü yolu inhibitörü (DFY‹), fibrinojen, von Willebrand faktör (vWF) ve yüksek duyarl›kl› CRP (hsCRP) düzeyi belirlendi. Verilerin analizi SPSS 10 program› ile student-t ve Mann-Whitney U testleri kullan›larak yap›ld›. Bulgular: Çal›flma grubunda vWF düzeyleri kontrol grubuna göre daha yüksek bulundu [116,3±52,2 ve 86,8±41,4 ng/mL, (p

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Cite This Article

DİNDAR, A., NİŞLİ, K., AYDOĞAN, Ü., ÖMEROĞLU, E. R., YAVUZ, T., BORNAUN, H., ÖNER, C. N., ERTUĞRUL, T., TÜRKOĞLU, Ü. (2022). Endotel function and thrombotic system evaluation of children whose parents had early onset coronary heart disease. Türk Pediatri Arşivi, Cilt: 46 - Sayı: 1, 20–25. https://ajindex.com/articles/641422

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