Journals / Türk Pediatri Arşivi / 2019 / Cilt: 54 - Sayı: 4

The relationship between cardiometabolic risks and vitamin D levels with the degree of obesity

Şişmanlığın derecesi ile kardiyometabolik riskler ve vitamin D düzeyi arasındaki ilişki

Pages
256–263
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The body mass index standard deviation had a positive correlation with the number of cardiometabolic risk factors (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: The aim of this study was to evaluate the cardiometabolic risk factors including vitamin D levels according to the degree of obesity in adolescents.
📊
Key Findings & Data:A total of 363 overweight/obese adolescents aged between 11 and 18 years who were evaluated in our clinic from January 2012 to December 2015 were included in the study.
💡
Conclusion & Impact:The body mass index standard deviation had a positive correlation with the number of cardiometabolic risk factors (p
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: The aim of this study was to evaluate the cardiometabolic risk factors including vitamin D levels according to the degree of obesity in adolescents. Material and Methods: This is a retrospective cross-sectional study. A total of 363 overweight/obese adolescents aged between 11 and 18 years who were evaluated in our clinic from January 2012 to December 2015 were included in the study. The degree of obesity was calculated as the body mass index standard deviation. Hypertension, dyslipidemia, hyperinsulinemia, hyperglycemia, insulin resistance, and vitamin D deficiency were defined as cardiometabolic risk factors. Mann-Whitney U, Chi-square, Spearman and Pearson’s correlation tests, and linear regressions analyses were used for statistical analyses. Results: Of the 319 (n=319/363) adolescents, all of whose cardiometabolic risk factors were known, 267 (85.7%) had at least one cardiometabolic risk factor. The body mass index standard deviation had a positive correlation with the number of cardiometabolic risk factors (p

Özet

Amaç: Bu çalışmanın amacı ergenlerde obezite derecesine göre D vitamini düzeylerini içeren kardiyometabolik risk etmenlerini değerlendirmektir. Gereç ve Yöntemler: Bu çalışma geriye dönük kesitsel bir çalışmadır. Çalışmaya Ocak 2012–Aralık 2015 tarihleri arasında kliniğimizde değerlendirilen 11–18 yaş aralığında toplam 363 aşırı ağırlıklı/şişman ergen alındı. Şişmanlığın derecesi beden kitle indeksi standart sapması olarak hesaplandı. Hipertansiyon, dislipidemi, hiperinsülinemi, hiperglisemi, insülin direnci ve vitamin D eksikliği kardiyometabolik risk etmenleri olarak tanımlandı. İstatistiksel çözümlemelerde Mann-Whitney U, Ki-kare, Spearman ve Pearson korelasyon testleri ve linear regresyon çözümlemeleri kullanıldı. Bulgular: Tüm kardiyometabolik risk etmenleri bilinen 319 (n=319/363) ergenin 267 (%85,7) en az bir kardiyometabolik risk etmenine sahipti. Beden kitle indeksi standart sapması, kardiyometabolik risk etmeni sayısı ile aynı yönlü ilişki gösterdi (p=0,0001). Cinsiyet ve yaşın eş değişkenler olarak kabul edildiği linear regresyon modellerinde, beden kitle indeksi standart sapmasındaki bir birimlik artış, sistolik kan basıncında 6,085 mmHg, diyastolik kan basıncında 4,4 mmHg, HOMA-IR’de 1,59 puanlık, insülin seviyesinde %13’lük artışa; 25 hidroksi D vitamini seviyesinde 2,16 ng/ml azalmaya yol açıyordu. Çıkarımlar: Ergenlerde, obezite derecesi arttıkça kardiyometabolik risk etmeni sayısı artmaktadır. Şişmanlığın ciddiyetinin belirlenmesi, daha yüksek kan basıncı ve bozulmuş glukoz metabolizması ve daha düşük serum D vitamini seviyeleri için daha fazla risk altında olanları belirlemede yardımcı olabilir. Diğer taraftan obezite derecesi anormal lipid ve glukoz düzeylerinin varlığını yansıtmayabilir.

🔖

Cite This Article

KÖSE, S., VEHİD, S., ERCAN, O., ALİKAŞİFOĞLU, M., ÇELİK, E., GÜNEŞ, A. O., ERGİNOZ, E. (2022). The relationship between cardiometabolic risks and vitamin D levels with the degree of obesity. Türk Pediatri Arşivi, Cilt: 54 - Sayı: 4, 256–263. https://ajindex.com/articles/641002

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (4)

  1. WHO. Obesity and overweight, cited February 2018. Available from: http://www.who.int/en/news-room/factsheets/detail/obesity-and-overweight. Accsessed, August 15, 2018. 2. de Onis M, Martínez-Costa C, Núñez F, et al. Association between WHO cut-offs for childhood overweight and obesity and cardiometabolic risk. Public Health Nutr 2013;16: 625−30. [CrossRef] 3. Reinehr T, Andler W, Denzer C, Siegried W, Mayer H, Wabitsch M. Cardiovascular risk factors in overweight German children and adolescents: relation to gender, age and degree of overweight. Nutr Metab Cardiovasc Dis 2005; 15: 181−7. [CrossRef] 4. Morais PR, Sousa AL, Jardim Tde S, et al. Correlation of Insulin resistance with Anthropometric Measures and Blood Pressure in Adolescents. [Article in English, Por tuguese]. Arq Bras Cardiol 2016; 106: 319−26. [CrossRef] 5. Skinner AC, Perrin EM, Moss LA, Skelton JA. Cardiometabolic Risks and Severity of Obesity in Children and Young Adults. N Engl J Med 2015; 373: 1307−17
  2. Makkes S, Renders CM, Bosmans JE, van der BaanSlootweg OH, Seidell JC. Cardiometabolic risk factors and quality of life in severely obese children and adolescents in The Netherlands. BMC Pediatr 2013; 13: 62−71
  3. Mandarino NR, Júnior Fd, Salgado JV, Lages JS, Filho NS. Is vitamin d deficiency a new risk factor for cardiovascular disease? Open Cardiovasc Med J 2015; 9: 40−9. [CrossRef] 8. Peterson CA, Tosh AK, Belenchia AM. Vitamin D insufficiency and insulin resistance in obese adolescents. Ther Adv Endocrinol Metab 2014; 5: 166−89. [CrossRef] 9. Pacifico L, Anania C, Osborn JF, et al. Low 25(OH)D3 levels are associated with total adiposity, metabolic syndrome, and hypertension in Caucasian children and adolescents. Eur J Endocrinol 2011; 165: 603−11. [CrossRef] 10. Wakayo T, Whiting SJ, Belachew T. Vitamin D Deficiency is Associated with Overweight and/or Obesity among Schoolchildren in Central Ethiopia: A Cross-Sectional Study. Nutrients 2016; 8: 190−202. [CrossRef] 11. Field AE, Cook NR, Gillman MW. Weight status in childhood as a predictor of becoming overweight or hypertensive in early adulthood. Obes Res 2005; 13: 163−9
  4. Guo SS, Wu W, Chumlea WC, Roche AF. Predicting overweight and obesity in adulthood from body mass index values in childhood and adolescence. Am J Clin Nutr 2002; 76: 653−8. [CrossRef] 13. Franks PW, Hanson RL, Knowler WC, Sievers ML, Bennett PH, Looker HC. Childhood obesity, other cardiovascular risk factors, and premature death. N Engl J Med 2010; 362: 4