Dilde kitle ile ortaya çıkan metastatik renal hücreli karsinom

Conclusion & Impact:The metastasis of renal cell carcinoma should always be considered in the differential diagnosis among the clear cell neoplasms.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

Renal cell carcinoma is one of the most common tumours after lung and breast cancer to metastasize to the head and neck. Initial presentation by tongue metastasis is extremely rare. A 67-year-oldmale presented with a 4.8 cm mass on his tongue. The result of the punch biopsy from the tongue was diagnosed as a clear cell variant of squamous cell carcinoma. The biopsy was reevaluated due to the renal mass found during the check-up and the rapid enlargement of the mass. The excision of the tongue mass and the radical nephrectomy material confirmed the diagnosis of a metastatic renal cell carcinoma in the tongue and renal cell carcinoma in the kidney. Since metastasis of renal cell carcinoma to the tongue is uncommon it may cause difficulties in diagnosis and proper management. The metastasis of renal cell carcinoma should always be considered in the differential diagnosis among the clear cell neoplasms.

Özet

Baş ve boyun bölgesine renal hücreli karsinom metastazı meme ve akciğer tümörlerinden sonra en sık olarak görülür. Dil metastazı ile bulgu vermesi ise çok seyrektir. 67 yaşında erkek hasta dilde 4,8 cm çapında kitle ile başvurdu. Dilden alınan insizyonel biyopsi sonucu berrak hücre varyant skuamöz hücreli karsinom yönündeydi. Görüntüleme yöntemiyle böbrekte kitle saptanması ve dil kitlesinin çok hızlı büyümesi nedeniyle biyopsi yeniden incelendi. Böbrek tümörü metastazının öncelikle düşünülmesi üzerine, kitlenin total eksizyonu sonrası ve immünohistokimyasal yöntemin desteğiyle, radikal nefrektomideki tümör ile aynı nitelikte, dile metastatik berrak hücreli renal hücreli karsinom tanısı konuldu. Renal hücreli karsinomun dile metastazı ender olması nedeniyle doğru tanıda ve tedavide zorluklara yol açmaktadır. Dilde ortaya çıkan berrak hücreli neoplaziler arasında renal hücreli karsinom metastazı ayırıcı tanıda akılda tutulmaktadır.

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Cite This Article

ETİT, D., TAN, A., ALTINEL, D., YALÇIN, Y., ERDOĞAN, G. I., BEYHAN, R., BULUT, V., BAYOL, Ü. (2022). Dilde kitle ile ortaya çıkan metastatik renal hücreli karsinom. Türk Patoloji Dergisi, Cilt: 26 - Sayı: 3, 261–263. https://ajindex.com/articles/640802

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References (1)

Zegarelli DJ, Tsukada Y, Pickren JW, Greene GW Jr: Metastatic tumor to the tongue. Report of twelve cases. Oral Surg Oral Med Oral Pathol 1973, 35:202-211 2) Friedlander, AH, Singer R: Renal adenocarcinoma of the kidney with metastasis to the tongue. J Am Dent Assoc 1978, 97: 989-991 3) Boles R, Cerny J: Head and neck metastases from renal carcinomas. Mich Med 1971, 70:616-618 4) Cheng ET, Greene D, Koch RJ: Metastatic renal cell carcinoma to the nose. Otolaryngol Head Neck Surg 2000,122: 464 5) Ziyada, WF, Brookes JD, Penman HG: Expectorated tissue leading to diagnosis of renal adenocarcinoma. J Laryngol Otol 1994, 108:1108-1110 6) Kapoor VK, Mukhopadhyay AK, Chattopadhyay TK, Sharma LK: Renal cell carcinoma metastatic to the tongue. J Indian Med Assoc 1987, 85:119-120 7) Azam F, Abubakerr M, Gollins S: Tongue metastasis as an initial presentation of renal cell carcinoma: a case report and literature review. J Med Case Reports 2008, 2:249 8) Aguirre A, Rinaggio J, Diaz-Ordaz E: Lingual metastasis of renal cell carcinoma. J Oral Maxillofac Surg 1996, 54:344-346 9) Shibayama T, Hasegawa S, Nakamura S, Tachibana M, Jitsukawa S, Shiotani A, Morinaga S: Disappearance of metastatic renal cell carcinoma to the base of the tongue after systemic administration of interferon-alpha. Eur Urol, 1993, 24: 297-299 10) Lang EE, Patil N, Walsh RM, Leader M, Walsh MA: A case of renal cell carcinoma metastatic to the nose and tongue. Ear Nose Throat J 2003, 82:382-383 11) Okabe Y, Ohoka H, Miwa T, Nagayama I, Furukawa M: View from beneath: pathology in focus. Renal cell carcinoma metastasis to the tongue. J Laryngol Otol 1992, 106:282-284