Journals / Türk Patoloji Dergisi / 2014 / Cilt: 30 - Sayı: 3

Over Tümörlerinde İntraoperatif Frozen İncelemenin Tanısal Yeri; Tek Merkez Deneyimi

Intraoperative Frozen Section in Ovarian Neoplasms; A Tertiary Center Experience

Pages
184–188
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: Overall diagnostic accuracy of frozen section was 96.5%.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Frozen section is an accurate diagnostic tool with some unavoidable pitfalls in gynecologic tumors.
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Key Findings & Data:Material and Method: Frozen section and paraffin section reports of 282 patients with ovarian neoplasms diagnosed between July 2006 and January 2013 in our institute were re-analyzed.
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Conclusion & Impact:Results: Overall diagnostic accuracy of frozen section was 96.5%.
🔬Design:Research Article
📍Scope:2006 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Frozen section is an accurate diagnostic tool with some unavoidable pitfalls in gynecologic tumors. We aimed to evaluate the diagnostic value of frozen section, and to detect the factors causing erroneous diagnosis in ovarian tumors. Material and Method: Frozen section and paraffin section reports of 282 patients with ovarian neoplasms diagnosed between July 2006 and January 2013 in our institute were re-analyzed. Results were grouped into benign, borderline (for epithelial tumors) and malignant categories and compared between frozen section and paraffin section diagnosis, statistically. Results: Overall diagnostic accuracy of frozen section was 96.5%. Sensitivity of frozen section for benign, borderline and malignant tumors were 97.5%, 95.8%, and 95.6% and the related specificities were 97.5%, 97.6%, and 100%, respectively. We found the lowest positive predictive value in borderline group (79.3%), all of them with mucinous type epithelium. Second frequent discordant tumor type was immature teratoma. Conclusion: Apart from the limitations of frozen section, pathologists should be aware of the pitfalls of technique and tumor types and tend to sample from the solid areas particularly in mucinous tumors and teratomas to avoid inappropriate surgery.

Özet

Amaç: Jinekolojik tümörler için frozen kesit inceleme bazı tanısal tuzaklara karşın yeterli bir tanısal yöntemdir. Bu çalışmada, over tümörlerinde frozen incelemenin tanısal değerini ve tanısal yanlışlıkların nedenlerini tespit etmeyi amaçladık. Gereç ve Yöntem: Kurumumuzda Haziran 2006 ve Ocak 2013 yılları arasında over tümörü nedeni ile frozen inceleme yapılmış olan toplam 282 hastaya ait sonuçlar yeniden değerlendirildi. Tanılar benign, borderline (epitelyal tümörler için) ve malign olmak üzere üç alt gruba ayrıldı. Frozen ve parafin kesit sonuçları istatistiksel olarak karşılaştırıldı. Bulgular: Frozen incelemenin genel tanısal doğruluk oranı %96,5 idi. Benign, borderline ve malign tümörler için frozen incelemenin duyarlığı sırasıyla %97,5, %95,8 ve %95,6 idi. Özgüllük ise aynı sırayla, %97,5, %97,6 ve %100 idi. En düşük pozitif prediktif değer borderline grubunda saptandı (%79,3) ve hataya neden olan tüm olgular müsinöz tip epitelyal tümörler idi. Tanı uyumsuzluğu bulunan ikinci tümör grubu ise immatür teratom idi. Sonuç: Frozen incelemenin kısıtlılıkları yanısıra, patoloğun frozen incelemenin teknik veya tümör tipi ile ilgili tuzaklarını bilmesi, özel- likle müsinöz tümörler ve teratom olgularında solid görünen alan- lardan örneklenmesi yetersiz veya gereksiz operasyon yapılmasını önlemek adına yararlı olacaktır.

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Cite This Article

AÇIKALIN, A., BAĞIR, E., GÜMÜRDÜLÜ, D., ZEREN, H., BAYRAM, F., TORUN, G. (2022). Over Tümörlerinde İntraoperatif Frozen İncelemenin Tanısal Yeri; Tek Merkez Deneyimi. Türk Patoloji Dergisi, Cilt: 30 - Sayı: 3, 184–188. https://ajindex.com/articles/640611

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