Journals / Türk Patoloji Dergisi / 2020 / Cilt: 36 - Sayı: 1

Clinicopathologic Characteristics of Gallbladder Adenomyomas and the Contribution of Macroscopic Sampling in Adenomyoma Diagnosis

Pages
11–16
Publication Date
2022-11-06
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Whenwe conducted the sampling according to the last protocol, the increase in the diagnosis of adenomyoma showed that adequate and accuratesampling was very useful for the detection of adenomyoma in the gallbladder.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Adenomyoma, a reactive and hamartomatous lesion of the gallbladder, is included in the differential diagnosis of several benign andmalignant lesions.
📊
Key Findings & Data:Slides and demographic properties of the cases were reexamined.Results: While adenomyoma was present in 22 of 1879 gallbladder before the protocol, it was observed in 32 of 1781 gallbladders in thepost-protocol period. 17 of the cases were male and 37 were female.
💡
Conclusion & Impact:Whenwe conducted the sampling according to the last protocol, the increase in the diagnosis of adenomyoma showed that adequate and accuratesampling was very useful for the detection of adenomyoma in the gallbladder.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Adenomyoma, a reactive and hamartomatous lesion of the gallbladder, is included in the differential diagnosis of several benign andmalignant lesions. Macroscopic sampling is very important in the determination of these lesions. The agreed macroscopy protocol in recentyears has been prepared by the Hepatopancreatobiliary Pathology Working Group. We aimed to evaluate the clinicopathologic properties ofadenomyoma cases in the gallbladder and the contribution of new macroscopy techniques to the diagnosis of adenomyoma in the pre-protocoland post-protocol parts of a one-year period.Material and Method: Two institutes were included in the study. Adenomyoma cases diagnosed in the pre-protocol and post-protocol periodsof one year duration were included in the study. Slides and demographic properties of the cases were reexamined.Results: While adenomyoma was present in 22 of 1879 gallbladder before the protocol, it was observed in 32 of 1781 gallbladders in thepost-protocol period. 17 of the cases were male and 37 were female. The mean age of the cases was 51.8. 52% of the lesions were located in thefundus. A gallstone was observed in 37 cases, and cholesterolosis in 14 cases. In the comparison of the two periods, the number of cases was lowerin the post-protocol period but a 0.6% increase in the diagnosis of adenomyoma was found.Conclusion: Adenomyoma is one of the lesions of the gallbladder that should be recognized but can be easily overlooked macroscopically. Whenwe conducted the sampling according to the last protocol, the increase in the diagnosis of adenomyoma showed that adequate and accuratesampling was very useful for the detection of adenomyoma in the gallbladder.

🔖

Cite This Article

ÖZER, M., KESER, S. H., ERHAN, S. Ş. (2022). Clinicopathologic Characteristics of Gallbladder Adenomyomas and the Contribution of Macroscopic Sampling in Adenomyoma Diagnosis. Türk Patoloji Dergisi, Cilt: 36 - Sayı: 1, 11–16. https://ajindex.com/articles/640411

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Joshi JK, Kirk L. Adenomyomatosis. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2018
  2. Pellino G, Sciaudone G, Candilio G, Perna G, Santoriello A, Canonico S, Selvaggi F. Stepwise approach and surgery for gallbladder adenomyomatosis: A mini-review. Hepatobiliary Pancreat Dis Int. 2013;12:136-42
  3. Bonatti M, Vezzali N, Lombardo F, Ferro F, Zamboni G, Tauber M, Bonatti G. Gallbladder adenomyomatosis: Imaging findings, tricks and pitfalls. Insights Imaging. 2017;8:243-53
  4. Nishimura A, Shirai Y, Hatakeyama K. Segmental adenomyomatosis of the gallbladder predisposes to cholecystolithiasis. J Hepatobiliary Pancreat Surg. 2004;11:342-7
  5. Golse N, Lewin M, Rode A, Sebagh M, Mabrut JY. Gallbladder adenomyomatosis: Diagnosis and management. J Visc Surg. 2017;154:345-53
  6. Adsay V, Saka B, Basturk O, Roa JC. Criteria for pathologic sampling of gallbladder specimens. Am J Clin Pathol. 2013;140:278-80
  7. Argon A, Yağcı A, Taşlı F, Kebat T, Deniz S, Erkan N, Kitapçıoğlu G, Vardar E. A different perspective on macroscopic sampling of cholecystectomy specimens. Korean J Pathol. 2013;47:519-25
  8. Esendağlı G, Akarca FG, Balcı S, Argon A, Erhan SŞ, Turhan N, Zengin Nİ, Keser SH, Çelik B, Bulut T, Abdullazade S, Erden E, Savaş B, Bostan T, Sağol Ö, Ağalar AA, Kepil N, Karslıoğlu Y, Günal A, Markoç F, Saka B, Özgün G, Özdamar ŞO, Bahadır B, Kaymaz E, Işık E, Ayhan S, Tunçel D, Yılmaz BÖ, Çelik S, Karabacak T, Seven İE, Çelikel ÇA, Gücin Z, Ekinci Ö, Akyol G. A retrospective evaluation of the epithelial changes/lesions and neoplasms of the gallbladder in Turkey and a review of the existing sampling methods: A multicentre study. Turk Patoloji Derg. 2018;34:41-8
  9. Pang L, Zhang Y, Wang Y, Kong J. Pathogenesis of gallbladder adenomyomatosis and its relationship with early-stage gallbladder carcinoma: An overview. Braz J Med Biol Res. 2018;51:e7411
  10. Frierson HF. Gallbladder and extrahepatic biliary system. In Stenberg SS, editor. Histology for pathologists. 2nd ed. Philadelphia: Lippincott-Raven, 1997;593-611
  11. Runner GJ, Corwin MT, Siewert B, Eisenberg RL. Gallbladder wall thickening. AJR. 2014; 202:W1-W12
  12. Dairi S, Demeusy A, Sill AM, Patel ST, Kowdley GC, Cunningham SC. Implications of gallbladder cholesterolosis and cholesterol polyps? J Surg Res. 2016; 200: 467-72
  13. Adsay V. Gallbladder, extrahepatic biliary tree and ampulla. In Mılls SE, editor. Stenberg’s Diagnostic Surgical Pathology. 5th ed. Philadelphia:Lippincott-Wil