Journals / Koşuyolu Heart Journal / 2013 / Cilt: 16 - Sayı: 3

Effect of Age on Postoperative Results in Elderly Coronary By-pass Patients

Koroner Baypas Hastalarında Postoperatif Sonuçlara Yaşın Etkileri

Pages
189–198
Publication Date
2012-03-01
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Although no signifi cant associations were found between age and mortality, age constitutes an independent risk factor for neurologic morbidity along with presence cerebrovascular disease.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Introduction: The purpose of this study is to analyze the outcome results of coronary by-pass operations from a single institution.
📊
Key Findings & Data:Patients and Methods: In this retrospective study, we analyzed the prospectively collected data of 510 coronary by-pass patients.
💡
Conclusion & Impact:Although no signifi cant associations were found between age and mortality, age constitutes an independent risk factor for neurologic morbidity along with presence cerebrovascular disease.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Koroner arter baypas grefti · nörolojik disfonksiyon · risk faktörleri

Abstract

Introduction: The purpose of this study is to analyze the outcome results of coronary by-pass operations from a single institution. The post-operative neurologic complications have been analyzed in detail in order to fi nd out the risk factors and the relation of age and occurrence of neurologic complications has been assessed. Patients and Methods: In this retrospective study, we analyzed the prospectively collected data of 510 coronary by-pass patients. Neurological morbidity and mortality were evaluated with logistic regression analysis for elderly patients. Results: Of these 510 patients, 382 (74.9%) were male and 89 (17.5%) were older than 70 years of age. Post-operative mortality, pulmonary and neurologic morbidity occurred in 27 (5.3%), 78 (15.3%) and 26 (5.1%) patients, respectively. The comparison of patients with ? 70 and > 70 years of age showed that the differences were signifi cant (mortality 4.0% vs. 11.2%, p= 0.012; pulmonary morbidity 13.5% vs. 23.6%, p= 0.022; neurologic morbidity 3.3% vs. 13.5%, p= 0.0001). Presence of cerebrovascular disease (odds ratio= 4.72; p= 0.014) and advanced age (odds ratio= 3.55; p= 0.016) were independent predictors of neurologic complications. Every year increase above 51.5 years of age was associated with 5.8% (p= 0.049) increased neurologic complication risk. Conclusion: Elderly patients have higher rates of mortality, pulmonary and neurologic morbidity after coronary by-pass operations. Although no signifi cant associations were found between age and mortality, age constitutes an independent risk factor for neurologic morbidity along with presence cerebrovascular disease.

Özet

Giriş: Bu çalışmanın amacı tek bir merkezde yaşlı hastalarda yapılan koroner baypas ameliyatlarının sonuçlarını analiz etmektir. Postoperatif nörolojik komplikasyonlar ayrıntılı olarak analiz edilmiş ve yaşla beraber diğer risk faktörlerinin nörolojik komplikasyonların oluşumuna etkisi incelenmiştir. Hastalar ve Yöntem: Bu retrospektif çalışmada 510 koroner baypas hastasının prospektif olarak toplanan verileri analiz edildi. Nörolojik morbidite ve mortalitenin yaşlı hastalarda görülme riski lojistik regresyon analiziyle incelendi. Bulgular: Çalışmada incelenen 510 hastanın 382 (%74.9)'si erkekti ve 89 (%17.5)'u 70 yaşın üzerindeydi. Postoperatif mortalite, pulmoner ve nörolojik komplikasyon sırasıyla 27 (%5.3), 78 (%15.3) ve 26 (%5.1) hastada görüldü. Yetmiş yaş ve altındaki hastalar ile 70 yaş üzerindekilerin karşılaştırılmasında bu değerler arasında istatistiksel olarak anlamlı fark mevcuttu (mortalite %4.0 ve %11.2, p= 0.012; pulmoner morbidite %13.5 ve %23.6, p= 0.022; nörolojik morbidite %3.3 ve %13.5, p= 0.0001). Serebrovasküler hastalık varlığı (OR= 4.72; p= 0.014) ve ileri yaş (OR= 3.55; p= 0.016) nörolojik komplikasyon gelişiminde anlamlı değişkenler olarak bulundu. Hastaların yaşının 51.5'in üzerinde olduğu her yıl için nörolojik komplikasyon gelişme riskinin %5.8 artmakta olduğu hesaplandı (p= 0.049). Sonuç: Yaşlı hastalarda yapılan koroner baypas ameliyatları sonrası mortalite, pulmoner ve nörolojik komplikasyonlar daha sık görülmektedir. Yaş ve mortalite arasında anlamlı bir ilişki olmasa da, ileri yaş ve serebrovasküler hastalık nörolojik komplikasyon görülme riskini artırmaktadır.

🔖

Cite This Article

Polat, A., Gümüş, F., Kuplay, H., Yücel, C., Sönmez, S., Sarıoğlu, S., Erentuğ, V. (2012). Effect of Age on Postoperative Results in Elderly Coronary By-pass Patients. Koşuyolu Heart Journal, Cilt: 16 - Sayı: 3, 189–198. https://ajindex.com/articles/64030

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (8)

  1. Bardakci H, Cheema FH, Topkara VK, Dang NC, Martens TP, Mer- cando ML, et al. Discharge to home rates are signifi cantly lower for octogenarians undergoing coronary artery bypass graft sur- gery. Ann Thorac Surg 2007;83:483-9.
  2. Polat A, Tekümit H, Cenal AR, Tataroğlu C, Uzun K, Mert B, et al. Mid-term results of coronary artery bypass graft surgery in pa- tients 70 years of age or older. Turkish J Thorac Cardiovasc Surg 2012;20:467-73.
  3. Katz NM, Hannan RL, Hopkins RA, Wallace RB. Cardiac opera- tions in patients aged 70 years and over: mortality, length of stay, and hospital charge. Ann Thorac Surg 1995;60:96-100.
  4. Halkos ME, Puskas JD, Lattouf OM, Kilgo P, Guyton RA, Thourani VH. Impact of preoperative neurologic events on outcomes after coronary artery bypass grafting. Ann Thorac Surg 2008;86:504- 10. Bucerius J, Gummert JF, Borger MA, Walther T, Doll N, Falk V, et al. Predictors of delirium after cardiac surgery delirium: effect of beating-heart (off-pump) surgery. J Thorac Cardiovasc Surg 2004;127:57-64.
  5. Tokmakoglu H, Kandemir Ö, Farsak B, Günaydın S, Aydın H, Yorgancıoğlu C, et al. Yetmişbeş yaş üstü hastalarda koroner bay- pass cerrahisi ve sonuçları. Türk Kardiyol Der Ars 2002;30:737- 42. Chaturvedi RK, Blaise M, Verdon J, Iqbal S, Ergina P, Cecere R, et al. Cardiac surgery in octogenarians: long-term survival, function- al status, living arrangements, and leisure activities. Ann Thorac Surg 2010;89:805-10.
  6. Sen B, Niemann B, Roth P, Aser R, Schönburg M, Böning A. Short- and long-term outcomes in octogenarians after coronary artery bypass surgery. Eur J Cardiothorac Surg 2012;42:e102-7. Breuer AC, Furlan AJ, Hanson MR, Lederman RJ, Loop FD, Cos- grove DM, et al. Central nervous system complications of coro- nary artery bypass graft surgery: prospective analysis of 421 pa- tients. Stroke 1983;14:682-7.
  7. Furnary AP, Zerr KJ, Grunkemeier GL, Starr A. Continuous intra- venous insulin infusion reduces incidence of deep sternal wound infection in diabetic cardiac surgery patients. Ann Thorac Surg 1999;67:352-62.
  8. Lopes JA, Fernandes P, Jorge S, Goncalves S, Alvarez A, Costa e Silva Z, et al. Acute kidney injury in intensive care unit patients: a comparison between the RIFLE and the Acute Kidney Injury Net- work classifi cations. Crit Care 2008;12:R110. Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P; Acute Dialysis Quality Initiative workgroup. Acute renal failure-defi nition, outcome measures, animal models, fl uid therapy and information technology needs: