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Journals / Koşuyolu Heart Journal / 2014 / Cilt: 17 - Sayı: 1

Inflammation and Non-atherosclerotic Coronary Artery Aneurysm

Ateroskleroza Bağlı Olmayan Koroner Arter Anevrizması ve İnflamasyon İlişkisi

Mete GÜRSOY
Abdulkadir Faruk HÖKENEK
Vedat BAKUY
Egemen DUYGU
Murat ŞENER
Pages
11–14
Publication Date
2013-01-01
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

METHODS: Sixty individuals with CagA+ HP infection were compared with 40 individuals with CagA(-) HP infection and 50 individuals with no infection in terms of flow-mediated dilatation (FMD), non-endothelium-dependent dilatation (NED) and CRP.RESULTS: In the CagA+ subjects the mean percentage of FMD was 6.3±2.7, which was significantly lower than that of the CagA- subjects (9.8±3.3, p

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: Cytotoxin associated gene (Cag) A+ Helicobacter pylori (HP) is the most virulent HP strain, and its association with endothelial dysfunction remains unclear.
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Key Findings & Data:Thus we investigated the effects of CagA+ HP on endothelial dependent dilatation and its relationship with C-reactive protein (CRP) in normotensive subjects.
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Conclusion & Impact:METHODS: Sixty individuals with CagA+ HP infection were compared with 40 individuals with CagA(-) HP infection and 50 individuals with no infection in terms of flow-mediated dilatation (FMD), non-endothelium-dependent dilatation (NED) and CRP.RESULTS: In the CagA+ subjects the mean percentage of FMD was 6.3±2.7, which was significantly lower than that of the CagA- subjects (9.8±3.3, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Sitotoksin ilişkili gen A protein · Helicobacter pylori · akım aracılı dilatasyon

Abstract

OBJECTIVE: Cytotoxin associated gene (Cag) A+ Helicobacter pylori (HP) is the most virulent HP strain, and its association with endothelial dysfunction remains unclear. Thus we investigated the effects of CagA+ HP on endothelial dependent dilatation and its relationship with C-reactive protein (CRP) in normotensive subjects. METHODS: Sixty individuals with CagA+ HP infection were compared with 40 individuals with CagA(-) HP infection and 50 individuals with no infection in terms of flow-mediated dilatation (FMD), non-endothelium-dependent dilatation (NED) and CRP.RESULTS: In the CagA+ subjects the mean percentage of FMD was 6.3±2.7, which was significantly lower than that of the CagA- subjects (9.8±3.3, p

Özet

AMAÇ: Coronary artery aneurysm is generally presented as an asymptomatic, incidental angiographic finding and is often associated with atherosclerosis. In this study we investigated the relation of non-atherosclerotic isolated coronary artery aneurysm with inflammation.YÖNTEMLER: SİAGHP enfeksiyonu olan 60 kişi, sitotoksin ilişkili A geni negatif H. pylori (SAİGNHP) enfeksiyonlu 40 kişi ve enfeksiyonu olmayan 50 kişi ile akım aracılı dilatasyon (AAD), endotele bağımlı olmayan dilatasyon (EBOD) ve CRP düzeyleri yönünden karşılaştırıldı.BULGULAR: SİAGHP'li bireylerde ortalama AAD'nin yüzdesi (6.3±2.7) SİAGNHP olanlardan (9.8±3.3, p

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Cite This Article

GÜRSOY, M., HÖKENEK, A. F., BAKUY, V., DUYGU, E., ŞENER, M. (2013). Inflammation and Non-atherosclerotic Coronary Artery Aneurysm. Koşuyolu Heart Journal, Cilt: 17 - Sayı: 1, 11–14. https://ajindex.com/articles/64009

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