Journals / Türk Onkoloji Dergisi / 2006 / Cilt: 21 - Sayı: 4

Cutaneous metastasis of epidermoid carcinoma of the larynx: A case report

Larinks kanserli cilt metastazlı bir olgu sunumu

Pages
210–214
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Cutaneous metastasis may be the first sign of local failure, of distant metastasis, or even of the undetected laryngeal carcinoma with poor prognosis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The frequency of distant metastasis of epidermoid carcinoma of the larynx is between 6.5-7.2%.
📊
Key Findings & Data:Cutaneous metastasis is very rare.a 56-year-old male with locally advanced larynx carcinoma who received curative radiochemotheraphy a year ago was presented to our department with subcutaneous nodular lesions, and fatigue.
💡
Conclusion & Impact:Cutaneous metastasis may be the first sign of local failure, of distant metastasis, or even of the undetected laryngeal carcinoma with poor prognosis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The frequency of distant metastasis of epidermoid carcinoma of the larynx is between 6.5-7.2%. The common sites of metastasis are lung, liver and bone. Cutaneous metastasis is very rare.a 56-year-old male with locally advanced larynx carcinoma who received curative radiochemotheraphy a year ago was presented to our department with subcutaneous nodular lesions, and fatigue. Physical examination revealed 0.5 cm sized, and 1x1cm sized subcutaneous nodular lesions in the right arm, and in the parasternal area, respectively. Histopathologic examination confirmed the skin metastasis of epidermoid carcinoma of the larynx. The patient has profound anemia, hypercalcemia, hypernatremia, and hyperglicemia with complicated diabetic foot. Although the symptomatic treatment began immediately, the patient died on the third day of hospitalisation. Cutaneous metastasis may be the first sign of local failure, of distant metastasis, or even of the undetected laryngeal carcinoma with poor prognosis.

Özet

Epidermoid larinks karsinomunda uzak metastaz yaklaşık %6.5%7.2 oranında görülmektedir. Sıklıkla akciğer, karaciğer ve kemiğe yayılım saptanmakla birlikte cilt metastazı oldukça nadir görülür. Bir yıl önce lokal ileri evre larinks kanseri tanısı ile kliniğimizde küratif radyokemoterapi yapıldıktan sonra takibe alınan 56 yaşındaki erkek hasta, Mayıs 2006 tarihinde genel durum bozukluğu nedeniyle başvurdu. Fizik muayenesinde, sağ üst kol medialinde 0.5 cm ve sternum sağ yanında 1x1 cm çapında, mobil, düzgün sınırlı iki adet subkutan nodül ve diabetik ayak saptandı. Göğüs duvarındaki lezyon eksizyonel biyopsi ile çıkarıldı ve mikroskopik olarak primer tümör ile uyumlu cilt metastazı olduğu görüldü. Hastanın cilt metastazı dışında lokal veya uzak tutuluma rastlanmadı. Rutin kan ve biyokimya tetkileri sonucunda, anemi, hiperkalsemi, hiperglisemi ve hipernatremi bulundu. Semptomatik tedaviye rağmen genel durumu kötüleşmeye devam eden hasta hastaneye yatırılışının 3. gününde kaybedildi. Cilt metastazı, uzak metastatik yayılımın, lokal bölgesel yinelemenin veya daha önce bulgu vermemiş larinks tümörünün ilk işareti olabilmektedir. Genellikle kötü prognoz göstergesi olduğu bilinmektedir.

🔖

Cite This Article

UZAL, C., İBİŞ, K., ALTANER, Ş., KARAGÖL, H., ALAS, C. R., ÇALOĞLU, M., SAYNAK, M., ÇALOĞLU, Y. V., İBİŞ, C. (2022). Cutaneous metastasis of epidermoid carcinoma of the larynx: A case report. Türk Onkoloji Dergisi, Cilt: 21 - Sayı: 4, 210–214. https://ajindex.com/articles/639401

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Ferlito A, Shaha AR, Silver CE, Rinaldo A, Mondin V. Incidence and sites of distant metastases from head and neck cancer. ORL J Otorhinolaryngol Relat Spec 2001;63(4):202-7
  2. Licitra L, Bernier J, Grandi C, Locati L, Merlano M, Gatta G, et al. Cancer of the larynx. Crit Rev Oncol Hematol 2003;47(1):65-80
  3. Welsh LW, Welsh JJ, Rizzo TA. Internal anatomy of the larynx and the spread of cancer. Ann Otol Rhinol Laryngol 1989;98(3):228-34
  4. Debois JM. Skin metastases from a laryngeal carcinoma: report of a case. Cutis 1996;57(4):264-6
  5. Yoskovitch A, Hier MP, Okrainec A, Black MJ, Rochon L. Skin metastases in squamous cell carcinoma of the head and neck. Otolaryngol Head Neck Surg 2001;124(3):248-52
  6. Perez LM, Shumway RA, Carson CC 3rd, Fisher SR, Hudson WR. Penile metastasis secondary to supraglottic squamous cell carcinoma: review of the literature. J Urol 1992;147(1):157-60
  7. Horiuchi N, Tagami H. Skin metastasis in laryngeal carcinoma. Clin Exp Dermatol 1992;17(4):282-3
  8. Bottoni U, Innocenzi D, Mannooranparampil TJ, Richetta A, Del Giudice M, Calvieri S. Inflammatory cutaneous metastasis from laryngeal carcinoma. Eur J Dermatol 2001;11(2):124-6
  9. Lewin JS, Cleary KR, Eicher SA. An unusual metastasis to the thumb in a laryngectomized tracheoesophageal speaker. Arch Otolaryngol Head Neck Surg 1997;123(9):1007-9
  10. Zbaren P, Greiner R, Kengelbacher M. Stoma recurrence after laryngectomy: an analysis of risk factors. Otolaryngol Head Neck Surg 1996;114(4):569-75
  11. Shamsadini S, Taheri A, Dabiri S, Damavandi KF, Salahi S. Grouped skin metastases from laryngeal squamous cell carcinoma and overview of similar cases. Dermatol Online J 2003;9(5):27
  12. Kubota Y, Mir LM, Nakada T, Sasagawa I, Suzuki H, Aoyama N. Successful treatment of metastatic skin lesions with electrochemotherapy. J Urol 1998;160(4):1426
  13. Hill S, Thomas JM. Use of the carbon dioxide laser to manage cutaneous metastases from malignant melanoma. Br J Surg 1996;83(4):509-12
  14. Krathen RA, Orengo IF, Rosen T. Cutaneous metastasis: a meta-analysis of data. South Med J 2003;96(2):164-7.