Plateletcrit and Platelet Distribution Width as Independent Predictors of Coronary Artery Ectasia

Hikmet HAMUR; Kamuran KALKAN; Hakan DUMAN; Murtaza Emre DURAKOĞLUGİL; Zafer KÜÇÜKSU; Sinan İNCİ; Erkan YILDIRIM

Journals / Koşuyolu Heart Journal / 2016 / Cilt: 19 - Sayı: 3

Plateletcrit and Platelet Distribution Width as Independent Predictors of Coronary Artery Ectasia

Plateletkrit ve Trombosit Dağılım Genişliği Koroner Arter Ektazisinin Bağımsız Öngördürücüsüdür

Hikmet HAMUR

Kamuran KALKAN

Hakan DUMAN

Murtaza Emre DURAKOĞLUGİL

Zafer KÜÇÜKSU

Sinan İNCİ

Erkan YILDIRIM

Journal: Koşuyolu Heart Journal
Issue: 2016 · Cilt: 19 - Sayı: 3
Pages: 173–178
Publication Date: 2016-12-01
DOI: —

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AI Summary & Key Takeaways

AI Insight

⚡ TL;DR(Too Long; Didn't Read)

Conclusion: This study demonstrates that PCT and PDW are independent predictors of CAE.

📌 3 Key Takeaways

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Objective & Hypothesis: Introduction: Coronary artery ectasia (CAE) is characterised by an abnormal dilatation of the coronary arteries.

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Key Findings & Data:Patients and Methods: The study group included 51 patients (38 men; mean age: 52 ± 9.9 years) with isolated CAE and 50 individuals with normal coronary arteries (39 men; mean age: 54 ± 11.3 years).

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Conclusion & Impact:Conclusion: This study demonstrates that PCT and PDW are independent predictors of CAE.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Koroner arter ektazisi · koroner arter hastalığı · ortalama trombosit hacmi

Abstract

Introduction: Coronary artery ectasia (CAE) is characterised by an abnormal dilatation of the coronary arteries. Platelet volume indices, including the mean platelet volume (MPV), platelet distribution width (PDW), plateletcrit (PCT) and platelet count, are indicators of platelet activation. In this study, we investigated platelet volume indices in patients with CAE. Patients and Methods: The study group included 51 patients (38 men; mean age: 52 ± 9.9 years) with isolated CAE and 50 individuals with normal coronary arteries (39 men; mean age: 54 ± 11.3 years). Admission platelet volume indices were measured as part of the automated complete blood count. Results: Platelet count, MPV, PCT and PDW were higher in CAE than in the control group (p< 0.05). Multivariate analysis revealed PDW (odds ratio: 0.22, 95% confidence interval: 0.06-0.73, p= 0.013) and PCT (odds ratio: 3.41, 95% confidence interval: 1.66-6.98, p≤ 0.001) as independent predictors of CAE. Conclusion: This study demonstrates that PCT and PDW are independent predictors of CAE.

Özet

Giriş: Koroner arter ektazisi (KAE), koroner arterlerin anormal genişlemesi ile karakterize edilir. Ortalama trombosit hacmi (OTH), trombosit dağılım genişliği (TDG), plateletkrit (PKT) dahil olmak üzere trombosit hacmi endeksleri ve trombosit sayısı trombosit aktivasyonunun göstergeleridir. Bu çalışmada KAE’li hastalarda trombosit hacmi endeksleri incelendi.Hastalar ve Yöntem: Çalışmaya, izole KAE’si olan 51 (38 erkek; ortalama yaş: 52 + 9.9 yıl) hasta ve koroner arterleri normal olan 50 (39 erkek; ortalama yaş: 54 + 11.3 yıl) sağlıklı birey dahil edildi. Başvuruda trombosit hacmi endeksleri otomatik tam kan sayımı parçası olarak ölçüldü.Bulgular: Trombosit sayımı, OTH, PKT ve TDG, KAE grubunda kontrol grubuna göre daha yüksekti (p< 0.05). Çok değişkenli lojistik regresyon analizinde, TDG (Odds oranı: 0.22, %95 güven aralığı: 0.06-0.73, p= 0.013) ve PKT’nin (Odds oranı: 3.41, %95 güven aralığı: 1.66-6.98, p≤ 0.001) KAE’nin bağımsız öngördürücüleri olduğu gösterildi. <!-- /* Font Definitions */ @font-face {font-family:Arial; panose-1:2 11 6 4 2 2 2 2 2 4; mso-font-charset:0; mso-generic-font-family:auto; mso-font-pitch:variable; mso-font-signature:3 0 0 0 1 0;} @font-face {font-family:"ＭＳ明朝"; panose-1:0 0 0 0 0 0 0 0 0 0; mso-font-charset:128; mso-generic-font-family:roman; mso-font-format:other; mso-font-pitch:fixed; mso-font-signature:1 134676480 16 0 131072 0;} @font-face {font-family:"Cambria Math"; panose-1:2 4 5 3 5 4 6 3 2 4; mso-font-charset:1; mso-generic-font-family:roman; mso-font-format:other; mso-font-pitch:variable; mso-font-signature:0 0 0 0 0 0;} @font-face {font-family:Cambria; panose-1:2 4 5 3 5 4 6 3 2 4; mso-font-charset:0; mso-generic-font-family:auto; mso-font-pitch:variable; mso-font-signature:3 0 0 0 1 0;} @font-face {font-family:MinionPro-Regular; panose-1:0 0 0 0 0 0 0 0 0 0; mso-font-alt:"Minion Pro"; mso-font-charset:77; mso-generic-font-family:auto; mso-font-format:other; mso-font-pitch:auto; mso-font-signature:3 0 0 0 1 0;} /* Style Definitions */ p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; margin:0cm; margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:12.0pt; font-family:Cambria; mso-ascii-font-family:Cambria; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"ＭＳ明朝"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Cambria; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} p.TemelParagraf, li.TemelParagraf, div.TemelParagraf {mso-style-name:"\[Temel Paragraf\]"; mso-style-priority:99; mso-style-unhide:no; margin:0cm; margin-bottom:.0001pt; line-height:120%; mso-pagination:none; mso-layout-grid-align:none; text-autospace:none; font-size:12.0pt; font-family:MinionPro-Regular; mso-fareast-font-family:"ＭＳ明朝"; mso-fareast-theme-font:minor-fareast; mso-bidi-font-family:MinionPro-Regular; color:black; mso-ansi-language:EN-GB;} .MsoChpDefault {mso-style-type:export-only; mso-default-props:yes; font-family:Cambria; mso-ascii-font-family:Cambria; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"ＭＳ明朝"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Cambria; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} @page WordSection1 {size:612.0pt 792.0pt; margin:72.0pt 90.0pt 72.0pt 90.0pt; mso-header-margin:36.0pt; mso-footer-margin:36.0pt; mso-paper-source:0;} div.Wo

Keywords

Koroner arter ektazisi koroner arter hastalığı ortalama trombosit hacmi trombosit dağılım genişliği Coronary artery ectasia coronary artery disease mean platelet volume platelet distribution width

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Cite This Article

HAMUR, H., KALKAN, K., DUMAN, H., DURAKOĞLUGİL, M. E., KÜÇÜKSU, Z., İNCİ, S., YILDIRIM, E. (2016). Plateletcrit and Platelet Distribution Width as Independent Predictors of Coronary Artery Ectasia. Koşuyolu Heart Journal, Cilt: 19 - Sayı: 3, 173–178. https://ajindex.com/articles/63936

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