Primary meningeal-derived sarcomas are rare, and differential diagnosis with other meningeal mesenchymal tumors is based on the findings of morphological and immunohistochemical analyses.
📌 3 Key Takeaways
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Objective & Hypothesis:Primary or metastatic dura mater sarcomas are rarely seen, and dural synovial sarcomas are quite rare.Here we report the case of a 60-year-old man who presented with headache, nausea, and vomiting andwas found to have a 63×33×40-mm mass with solid and cystic components in parieto-occipital lobe.
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Key Findings & Data:Themass was resected completely, with no residue detected on postoperative magnetic resonance imagining.On pathological evaluation, a vimentin-, S100-, transducer-like enhancer of split 1-, BCL-2-, and EMApositive and desmin-, PR-, CD99-, PANCK-, and GFAP-negative synovial sarcoma with Ki-67 proliferation index of 12% was detected.
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Conclusion & Impact:Primary meningeal-derived sarcomas are rare, and differential diagnosis with other meningeal mesenchymal tumors is based on the findings of morphological and immunohistochemical analyses.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
Primary or metastatic dura mater sarcomas are rarely seen, and dural synovial sarcomas are quite rare.Here we report the case of a 60-year-old man who presented with headache, nausea, and vomiting andwas found to have a 63×33×40-mm mass with solid and cystic components in parieto-occipital lobe. Themass was resected completely, with no residue detected on postoperative magnetic resonance imagining.On pathological evaluation, a vimentin-, S100-, transducer-like enhancer of split 1-, BCL-2-, and EMApositive and desmin-, PR-, CD99-, PANCK-, and GFAP-negative synovial sarcoma with Ki-67 proliferation index of 12% was detected. Postoperatively, chemotherapy has been started, and it will be followed byradiotherapy. Primary meningeal-derived sarcomas are rare, and differential diagnosis with other meningeal mesenchymal tumors is based on the findings of morphological and immunohistochemical analyses.
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Cite This Article
AKDENİZ, N., YERLİKAYA, H., IŞIKDOĞAN, A., KÜÇÜKÖNER, M., KARHAN, O., KAPLAN, M. A., TEKE, F., URAKÇI, Z. (2022). Rare Occurrence of Synovial Sarcoma Originating from Dura Mater. Türk Onkoloji Dergisi, Cilt: 34 - Sayı: 1, 52–55. https://ajindex.com/articles/639202
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