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Journals / Koşuyolu Heart Journal / 2020 / Cilt: 23 - Sayı: 1

Evaluation of the Neutrophil-lymphocyte Ratio and Mean Platelet Volume in Hypertensive Patients with Coronary Artery Ectasia

Koroner Arter Ektazi Olan Hipertansif Hastalarda Nötrofil-Lenfosit Oranının ve Ortalama Trombosit Hacminin Değerlendirilmesi

Mehmet İNANIR
Gökhan ALICI
Emrah ACAR
Hayati EREN
Müjgan GÜRLER
Sait ALAN
Pages
59–63
Publication Date
2020-04-01
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: The neutrophil counts [4.2 (2.4-8.6) vs. 4.2 (2.0-6.7) u/mm3 , p= 0.015], red cell distribution width [15.7 (12.8-21.6) vs. 15.3 (13.2-18.6) %, p= 0.002], platelet distribution width [17.9 (15.5-23.0) vs. 17.5 (15.9-20.8) %, p= 0.001], NLR [2.1 (0.7-12.8) vs. 1.9 (0.8-4.5), p

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: Coronary artery ectasia (CAE) is associated with increased morbidity and mortality, and is known to also be associated with atherosclerosis.
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Key Findings & Data:Patients and Methods: The study was designed retrospectively in the cardiology unit of Bolu Abant Izzet Baysal University Medical Faculty Hospital between January 2017 and October 2019.
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Conclusion & Impact:Results: The neutrophil counts [4.2 (2.4-8.6) vs. 4.2 (2.0-6.7) u/mm3 , p= 0.015], red cell distribution width [15.7 (12.8-21.6) vs. 15.3 (13.2-18.6) %, p= 0.002], platelet distribution width [17.9 (15.5-23.0) vs. 17.5 (15.9-20.8) %, p= 0.001], NLR [2.1 (0.7-12.8) vs. 1.9 (0.8-4.5), p
🔬Design:Research Article
📍Scope:2017 Verileri
⚙️Variables:Hipertansiyon · inflamasyon · koroner arter ektazi

Abstract

Introduction: Coronary artery ectasia (CAE) is associated with increased morbidity and mortality, and is known to also be associated with atherosclerosis. CAE is considered a variant of coronary artery disease, and is more common in patients with hypertension. We aimed to evaluate the neutrophil-lymphocyte ratio (NLR) and mean platelet volume (MPV) in hypertensive patients with CAE. Patients and Methods: The study was designed retrospectively in the cardiology unit of Bolu Abant Izzet Baysal University Medical Faculty Hospital between January 2017 and October 2019. A total of 7287 coronary angiographies were retrospectively analyzed to detect the incidence of ischemic heart disease. Diagnosis of CAE was made visually by two cardiologists who were blinded to the study aims. All included patients had a diagnosis of hypertension. After appropriate exclusions, hypertensive patients were divided into CAE and normal coronary artery groups, and the laboratory parameters of the two groups were compared. Results: The neutrophil counts [4.2 (2.4-8.6) vs. 4.2 (2.0-6.7) u/mm3 , p= 0.015], red cell distribution width [15.7 (12.8-21.6) vs. 15.3 (13.2-18.6) %, p= 0.002], platelet distribution width [17.9 (15.5-23.0) vs. 17.5 (15.9-20.8) %, p= 0.001], NLR [2.1 (0.7-12.8) vs. 1.9 (0.8-4.5), p

Özet

Giriş: Artmış morbidite ve mortalite ile ilişkili olan koroner arter ektazi (KAE), ateroskleroz ile ilişkilidir ve koroner arter hastalığının bir varyantı olarak kabul edilir. KAE hipertansiyonu olan hastalarda daha yaygındır. Bu çalışmada, hipertansif KAH olan hastalarda nötrofil-lenfosit oranını (NLR) ve ortalama trombosit hacmini (MPV) değerlendirmek amaçlanmıştır. Hastalar ve Yöntem: Çalışma Ocak 2017-Ekim 2019 tarihleri arasında Bolu Abant İzzet Baysal Üniversitesi Tıp Fakültesi Hastanesi kardiyoloji ünitesinde retrospektif olarak tasarlandı. Çalışmada 7287 koroner anjiyografi iskemik kalp hastalığını saptamak için retrospektif olarak incelendi. KAE tanısı görsel olarak iki kör kardiyolog tarafından konuldu. Çalışmaya dahil edilen tüm hastalarda hipertansiyon tanısı vardı. Uygun dışlamalar sonrasında hipertansif hastalar KAE ve normal koroner arter gruplarına ayrıldı. Bu iki grubun laboratuvar parametreleri karşılaştırıldı. Bulgular: Nötrofil sayısı [4.2 (2.4-8.6) vs. 4.2 (2.0-6.7) u/mm3 , p= 0.015], RDW [15.7 (12.8-21.6) vs. 15.3 (13.2-18.6) %, p= 0.002], PDW [17.9 (15.5-23.0) vs. 17.5 (15.9-20.8) %, p= 0.001], NLR [2.1 (0.7-12.8) vs. 1.9 (0.8-4.5), p

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Cite This Article

İNANIR, M., ALICI, G., ACAR, E., EREN, H., GÜRLER, M., ALAN, S. (2020). Evaluation of the Neutrophil-lymphocyte Ratio and Mean Platelet Volume in Hypertensive Patients with Coronary Artery Ectasia. Koşuyolu Heart Journal, Cilt: 23 - Sayı: 1, 59–63. https://ajindex.com/articles/63838

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References (15)

  1. Tony H, Meng K, Wu B, Zeng Q. Among ectasia patients with coexisting coronary artery disease, timi frame count correlates with ectasia size and markis type iv is the commonest. Cardiol Res Pract 2015;2015:282170
  2. Mavrogeni S. Coronary artery ectasia: from diagnosis to treatment. Hellenic J Cardiol 2010;51:158-63
  3. Ozcan OU, Gulec S. Coronary artery ectasia. Cor et Vasa 2013;55:e242-7
  4. Saglam M, Karakaya O, Barutcu I, Esen AM, Turkmen M, Kargin R, et al. Identifying cardiovascular risk factors in a patient population with coronary artery ectasia. Angiology 2007;58:698-703
  5. Harikrishnan S, Sunder K, Tharakan J, Titus T, Bhat A, Sivasankaran S, et al. Coronary artery ectasia: angiographic, clinical profile and follow-up. Indian Heart J 2000;52:547-53
  6. Yang JJ, Yang X, Chen ZY, Wang Q, He B, Du LS, et al. Prevalence of coronary artery ectasia in older adults and the relationship with epicardial fat volume by cardiac computed tomography angiography. J Geriatr Cardiol 2013;10:10
  7. HGWAPL B, Jegavanthan A, Kogulan T, Karunaratne R, Hewaratne U, Kodithuwakku N, et al. Coronary angiographic and clinical characteristics of patients with coronary artery ectasia; an experience from sri lanka. IJRS 2019;10:33429-33
  8. Sanyal S, Caccavo N. Is nitroglycerin detrimental in patients with coronary artery ectasia? A case report. Tex Heart Inst J 1998;25:140
  9. Brunetti ND, Salvemini G, Cuculo A, Ruggiero A, De Gennaro L, Gaglione A, et al. Coronary artery ectasia is related to coronary slow flow and inflammatory activation. Atherosclerosis 2014;233:636-40
  10. Dahhan A. Coronary artery ectasia in atherosclerotic coronary artery disease, inflammatory disorders, and sickle cell disease. Cardiovascular therapeutics 2015;33:79-88
  11. Olsen MH, Angell SY, Asma S, Boutouyrie P, Burger D, Chirinos JA, et l. A call to action and a lifecourse strategy to address the global burden of raised blood pressure on current and future generations: the lancet commission on hypertension. Lancet (London, England) 2016;388:2665-712
  12. Agita A, Alsagaff MT. Inflammation, immunity, and hypertension. Acta Med Indones 2017;49:158-65
  13. Rashid S, Gul U, Ali M, Sadiq T, Kiyani AM. Coronary artery ectasia: clinical and angiographic features. J Coll Physicians Surg Pak 2018;28:824-8
  14. Tandon V, Tandon AA, Kumar M, Mosebach CM, Balakumaran K. Coronary artery aneurysms: Analysis of comorbidities from the national inpatient sample. Cureus 2019;11:e4876
  15. Falaschetti E, Mindel