Journals / Türk Kolon ve Rektum Hastalıkları Dergisi / 2020 / Cilt: 30 - Sayı: 1

Melanosis of The Appendix Presenting with the Clinic of Acute Appendicitis

Akut Apandisit ile Bulgu Veren Appendiks Melanozisi

Pages
57–59
Publication Date
2022-11-06
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Although melanosis coli is seen as a benign disease, there are no accurate data about whether it increases the risk of colon cancer and the incidence of acute appendicitis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Laxative drugs are frequently used for chronic constipation.
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Key Findings & Data:The chronic use of laxatives, which contain anthraquinone, mostly causes melanosis coli.A 57-year-old male patient with a history of diabetes mellitus and coronary artery disease, had long-term laxative use due to chronic constipation.
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Conclusion & Impact:Although melanosis coli is seen as a benign disease, there are no accurate data about whether it increases the risk of colon cancer and the incidence of acute appendicitis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Laxative drugs are frequently used for chronic constipation. The chronic use of laxatives, which contain anthraquinone, mostly causes melanosis coli.A 57-year-old male patient with a history of diabetes mellitus and coronary artery disease, had long-term laxative use due to chronic constipation. The patient was admitted to the emergency service with the complaint of inflammatory abdominal pain that started in the epigastric region one day ago and migrated to the right lower quadrant. During the physical examination, right lower quadrant tenderness and rebound were positive. Imaging examinations and physical examination were consistent with acute appendicitis. The patient underwent an appendectomy via Mc Burney incision under general anesthesia. The postoperative follow-up period was complication-free and the patient was discharged on the second postoperative day. Postoperative specimen pathology was reported as an appendix with melanosis coli findings. The incidence of melanosis coli increases with the chronic use of laxative drugs. Although melanosis coli is seen as a benign disease, there are no accurate data about whether it increases the risk of colon cancer and the incidence of acute appendicitis.

Özet

Laksatif ilaçlar genellikle kronik konstipasyon şikayeti nedeniyle kullanılmaktadır. Antrakinon içerek laksatif ilaçların uzun süre kullanımı sıklıkla melanozis koliye sebep olmaktadır. Fifty-seven yaşında bilinen diyabet, koroner arter hastalığı, kronik konstipasyon nedeniyle uzun sureli laksatif kullanımı olan erkek hasta, bir gündür olan epigastrik bölgeden başlayan ve sağ alt kadrana migrasyon gösteren enflamatuvar tarzda karın ağrısı yakınması, iştahsızlık, bulantı ve kusma şikayeti ile acil servise başvurdu. Yapılan fizik muayenesinde sağ alt kadranda hassasiyet ve rebound pozitifti. Yapılan laboratuvar tetkiklerinde lökositozu olan, abdomen ultrasonografi ve fizik muayenesi akut apandisiti destekleyen hasta acil operasyona alındı. Hastaya genel anestezi altında Mc Burney insizyonla apendektomi uygulandı. Servis izleminde ek bir komplikasyon gözlenmeyen hasta, postoperatif ikinci gün taburcu edildi. Hastanın postoperatif spesimen patolojisi melanozis koli bulguları gösteren apendiks şeklinde raporlandı. Melanozis koli görülme insidansı kronik laksatif kullanımı ile birlikte artmaktadır. Melanozis koli benign bir hastalık olarak görülmekle birlikte, kolon kanser riskini ve akut apandisit insidansını arttırıp arttırmadığına yönelik kesin veriler bulunmamaktadır.

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Cite This Article

KAYA, T., AYDIN, C., EKMEKÇİ, S., AVCI, E. K., ATICI, S. D. (2022). Melanosis of The Appendix Presenting with the Clinic of Acute Appendicitis. Türk Kolon ve Rektum Hastalıkları Dergisi, Cilt: 30 - Sayı: 1, 57–59. https://ajindex.com/articles/634542

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