SavedAdd your journal

Journals / Türkiye Tıp Dergisi Dahili Tıp Bilimleri / 2002 / Cilt: 9 - Sayı: 4

The prevalences of HBV, HCV and HIV infection in patients with familial Mediterranean fever

Ailesel Akdeniz ateşi olan hastalarda hepatit B, C ve HIV virüs infeksiyonlarının prevalansı

Ahmet TÜZÜN
Ahmet ERDİL
Zeki YEŞİLOVA
Uğur MUŞABAK
Bülent TOY
Kemal DAĞALI
Necmettin KARAEREN
Hasan AYTA
Sait BAĞCI
Pages
141–144
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There was no statistically difference f or anti-HBs positivity between patient and control groups (p> 0.05).Conclusion: In conclusion, absence of any difference between the patient and healthy groups in view of HBsAg, anti-HBs, anti-HCV arid anti-HIVpositivity reveals that these agents do not imply in the pathogenesis of FMF.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: In this study, we aimed to determine the prevalences of HBV, HCVand HIVinfection retrospectively in patients with familial mediterranean fever (FMF).
📊
Key Findings & Data:Method: 74patients (73 male and !female with the mean age of 22.47 ± 3.56) and, age and sex matched 58 healthy persons for control group were included in this study.
💡
Conclusion & Impact:There was no statistically difference f or anti-HBs positivity between patient and control groups (p> 0.05).Conclusion: In conclusion, absence of any difference between the patient and healthy groups in view of HBsAg, anti-HBs, anti-HCV arid anti-HIVpositivity reveals that these agents do not imply in the pathogenesis of FMF.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: In this study, we aimed to determine the prevalences of HBV, HCVand HIVinfection retrospectively in patients with familial mediterranean fever (FMF). Method: 74patients (73 male and !female with the mean age of 22.47 ± 3.56) and, age and sex matched 58 healthy persons for control group were included in this study. Serum HBsAg, anti-HBs, anti-HCV and anti-HIV levels were measured with Enzyme Immunoassay (EIA). Results: In patients group, HBsAg, anti-HCV, and anti-HIVpositivity were not found in any patient (0/74, 0/73 and 0/73, retrospectively). Anti-HBs positivity were found 4.84% (3/62). Although HBsAg, anti-HCV, and anti-HIV positivity were not found in the control group, anti-HBs positivity were found 16% (8/50). There was no statistically difference f or anti-HBs positivity between patient and control groups (p> 0.05).Conclusion: In conclusion, absence of any difference between the patient and healthy groups in view of HBsAg, anti-HBs, anti-HCV arid anti-HIVpositivity reveals that these agents do not imply in the pathogenesis of FMF.

Özet

Amaç: Bu çalışmada, ailesel akdeniz ateşi (AAA) olgularında hepatit B virüsü (HBV), hepatit C virüsü (HCV) ve "human immunodeficiency virus (HIV)" infeksiyonu prevalanslannı retrospektif olarak araştırmayı amaçladik.Yöntem: Çalışmaya 74 hasta (73'ü erkek, Ti kadın, ortalama yaş 22.47 ± 3-56yıl) ile, kontrol grubu olarak yaş ve cinsiyet uyumlu 58 sağlıklı birey alındı. Serum HBsAg, anti-HBs, anti-HCVve anti-HIV düzeyleri "Enzyme Immunoassay (EIA)" yöntemi ile araştırıldı. Bulgular: Hasta grubunda HBsAg (0/74), anti-HCV (0/73) ve anti-HIV (0/73) hiçbir hastada saptanmadı. Anti-HBs ise 62 hastanın 3 (%4.84)'ünde tespit edildi. Kontrol grubunda HBsAg (0/58), anti-HCV (0/58) ve anti-HIV (0/54) hiçbir olguda saptanmazken, anti-HBs 50 bireyin 8 (%16)'inde tespit edildi. Anti-HBspozitifliği açısından hasta ve kontrol grubu arasında istatistiksel olarak anlamlı farklılık yoktu (p> 0.05). Yorum: Sonuç olarak, AAA olan hastalarda HBsAg, anti-HBs, anti-HCV ve anti-HIVprevalanslarının sağlıklı kişilerdekinden farklılık göstermemesi, bu etkenlerin AAA etyopatogenezi ile ilişkili olamayacağını ortaya koymaktadır.

🔖

Cite This Article

TÜZÜN, A., ERDİL, A., YEŞİLOVA, Z., MUŞABAK, U., TOY, B., DAĞALI, K., KARAEREN, N., AYTA, H., BAĞCI, S. (2022). The prevalences of HBV, HCV and HIV infection in patients with familial Mediterranean fever. Türkiye Tıp Dergisi Dahili Tıp Bilimleri, Cilt: 9 - Sayı: 4, 141–144. https://ajindex.com/articles/631295

References (17)

  1. Hamuryudan V, Özdoğan H, Yazıcı H. Other forms of vasculitis and pseudovasculitis. Balillieres Clin Rhe-umatol 1997; 11:335-55
  2. Koçak H, Çakar N, Hekimoğlu B, et al. The coexis¬tence of familial mediterranean fever and polyarteri-tis nodosa; report of case. Pediatr Nephrol 1996; 10: 631-3
  3. Özen S, Ben-Cherit E, Bakkaloğlu A, et al. Polyarte- ritis nodosa in patients with familial mediterranean fever (FMF): A concomitant disease or a feature of FMF? Semin Arthritis Rheum 2001; 30: 281-7
  4. Flatau E, Kohn D, Schiller D, et al. Henoch-Schönle- in syndrome in patients with familial mediterranean fever. Arthritis Rheum 1982; 25: 42-7
  5. Sachs D, Langevitz P, Morag B, et al. Polyarteritis nodosa and familial mediterranean fever. Br J Rhe- umatol 1987; 26:139-41
  6. Glikson M, Galun E, Schlesinger M, et al. Polyarte¬ ritis nodosa and familial mediterranean fever: A re¬ port of 2 cases and review of the literature. J Rhe- umatol 1989; 16: 536-9
  7. Tekin M, Yalçınkaya F, Turner N, e t al. Clinical, la¬ boratory and molecular characteristics of children with familial mediterranean fever-associated vasculi¬ tis. Ada Paediatr 2000; 89: 177-82
  8. Özdoğan H, Arısoy N, Kasapçapur Ö, et al. Vasculi¬ tis in familial mediterranean fever. J Rheumatol 1997; 24: 323-7
  9. Sezer N. Isolation of virus as cause of Behçet's dise¬ ase. Am J Ophthalmoll953; 36: 301-2
  10. Fye HK, Scah EK. Polyartheritis nodosa, Wegener's granulomatosis and other vasculitides. Basic and Cli¬ nical Immunology. 6th ed. USA: Saunder, 1987: 375-6
  11. Gay Robert M Jr, Ball Gene V. Arthritis and allied conditions. In: Koopman WJ (ed). Vasculitis. 13th ed. Baltimore: Williams & Wilkins, 1997:1491-524
  12. Cuellar ML, Garcia C, Molina JF. Cryoglobulinemia and other dysproteinemias, familial mediterranean fever and POEMS syndrome. Curr Opin Rheumatol 1995; 7: 58-68
  13. Hamuryudan V, Sonsuz A, Yurdakul S. More on he¬ patitis C virus and Behçet's syndrome [letter]. N -Engl J Med 1995; 333: 322
  14. Oğuz A, Sametoglu F, Erdoğan S. More on hepatitis C virus and Behçet's syndrome [letter]. N Engl J Med 1995; 333: 322
  15. Aksu K, Kabasakal Y, Sayıner A, et al. Prevalences of hepatitis A, B, C and E viruses in Behçet's disease. Rheumatology 1999; 38: 1279-81
  16. Münke H, Stöckmann F, Ramadori G. Possible asso¬ ciation between Behçet's syndrome and chronic he¬ patitis C virus infection [letter]. N Engl J Med 1995; 332:400-1
  17. Livneh A, Langevitz P, Zemer D, et al. Criteria for the diagnosis of fam